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Lung Cancer Screening: An Update, Discussion, and Look Ahead

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Abstract

Over the past few years there has been a great deal of debate about the status of lung cancer screening. The debate has focused on at least three areas: the unmet need to prove a mortality reduction from the screening tests being studied, the potential for these screening tests to produce harm, and the possible cost-effectiveness of an image-based screening program. In this manuscript, I review the chest imaging cohort and controlled trials that have been added to the evidence base over the past few years. I then discuss the evidence related to the areas that are currently debated, describe the ongoing trials that will help to clarify these issues, and speculate about the future.

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Disclosure

Dr. Mazzone served as a consultant at an advisory board meeting for the company Oncimmune; they are developing a blood test for lung cancer detection.

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  1. Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, A90, Cleveland, OH, 44195, USA

    Peter J. Mazzone

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  1. Peter J. Mazzone
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Correspondence to Peter J. Mazzone.

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Mazzone, P.J. Lung Cancer Screening: An Update, Discussion, and Look Ahead. Curr Oncol Rep 12, 226–234 (2010). https://doi.org/10.1007/s11912-010-0111-6

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