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Neurologic Complications and Considerations in HIV-Infected Persons

  • HIV/AIDS (R MacArthur, Section Editor)
  • Published:
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Abstract

Neurologic complications for HIV-infected persons retain significant prevalence despite an increasingly global use of antiretroviral therapies. Such complications are often ascribed to advanced immunosuppression; however, the most common neurologic problems for HIV-infected persons, distal sensory polyneuropathy and HIV-associated neurocognitive disorders, affect a significant proportion of patients who have successfully achieved immunologic restoration with normal or near-normal CD4 count levels and undetectable HIV RNA in the periphery. Understanding specific considerations for HIV-associated complications, including the epidemiology, risk factors, medication-adverse effects, and benefits of appropriate management, is vital for all providers caring for those with HIV. This review will describe such considerations, as well as providing a more detailed review of the most common neurologic complications of HIV infection, and will highlight some of the challenges involved with diagnosis, management, and long-term effects.

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Correspondence to Justin McArthur.

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McArthur, J., Smith, B. Neurologic Complications and Considerations in HIV-Infected Persons. Curr Infect Dis Rep 15, 61–66 (2013). https://doi.org/10.1007/s11908-012-0312-2

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