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Postmenopausal vaginitis

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Abstract

The importance of vaginitis in postmenopausal women will increase as the US population ages. With the withdrawal of estrogen, the vaginal environment changes dramatically. Along with physical changes, an overall decrease in the normal Lactobacillus-dominant flora and Candida colonization occurs. Trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis still occur in menopausal women but probably less commonly than in younger women. The effects of exogenous estrogen on these conditions remain unknown. Less common conditions such as desquamative inflammatory vaginitis and lichen sclerosus gain relative importance in this population.

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References and Recommended Reading

  1. Lipsky MS, Waters T, Sharp LK: Impact of vaginal antifungal products on utilization of health care services: Evidence from physician visits. J Am Board Fam Pract 2000, 13:178–182.

    PubMed  CAS  Google Scholar 

  2. Anderson MR, Klink K, Cohrssen A: Evaluation of vaginal complaints. JAMA 2004, 291:1368–1379.

    Article  PubMed  CAS  Google Scholar 

  3. Tobin JM, Harindra V: Attendance by older patients at a genitourinary medicine clinic. Sex Transm Infect 2001, 77:289–291.

    Article  PubMed  CAS  Google Scholar 

  4. Nyirjesy P, Peyton C, Weitz MV, et al.: Causes of chronic vaginitis: Analysis of a prospective database of affected women. Obstet Gynecol 2006, 108:1185–1191.

    PubMed  Google Scholar 

  5. Hillier SL: Normal vaginal flora. In Sexually Transmitted Diseases, 3rd edn. Edited by Holmes KK, Sparling PF, Mardh PA, et al. New York: McGraw-Hill; 1999:191–203.

    Google Scholar 

  6. Hawes SE, Hillier SL, Benedetti J, et al.: Hydrogen peroxide-producing lactobacilli and acquisition of vaginal infections. J Infect Dis 1996, 174:1058–1063.

    PubMed  CAS  Google Scholar 

  7. Sobel JD: Vulvovagnial candidosis. Lancet 2007, 369:1961–1971.

    Article  PubMed  Google Scholar 

  8. Cohen MS: Sexually transmitted diseases enhance HIV transmission: No longer a hypothesis. Lancet 1998, 351:5–7.

    Article  PubMed  Google Scholar 

  9. Cherpes TL, Meyn LA, Krohn MA, et al.: Association between acquisition of herpes simplex virus type 2 in women and bacterial vaginosis. Clin Infect Dis 2003, 37:319–325.

    Article  PubMed  Google Scholar 

  10. Hillier SL, Lau RJ: Vaginal microflora in postmenopausal women who have not received estrogen replacement therapy. Clin Infect Dis 1997, 25(Suppl 2):S123–S126.

    Article  PubMed  Google Scholar 

  11. North American Menopause Society: The role of local vaginal estrogen for treatment of vaginal atrophy in postmenopausal women: 2007 position statement of the North American Menopause Society. Menopause 2007, 14:357–369.

    Article  Google Scholar 

  12. Davila GW, Singh A, Karapanagiotou I, et al.: Are women with urogenital atrophy symptomatic? Am J Obstet Gynecol 2003, 188:382–388.

    Article  PubMed  Google Scholar 

  13. Bygdeman M, Swahn ML: Replens versus dienestrol cream in the symptomatic treatment of vaginal atrophy in postmenopausal women. Maturitas 1996, 23:259–263.

    Article  PubMed  CAS  Google Scholar 

  14. Raz R, Stamm WE: A controlled trial of intravaginal estriol in postmenopausal women with recurrent urinary tract infections. N Engl J Med 1993, 329:753–756.

    Article  PubMed  CAS  Google Scholar 

  15. Ballagh SA: Vaginal hormone therapy for urogenital and menopausal symptoms. Semin Reprod Med 2005, 23:126–140.

    Article  PubMed  CAS  Google Scholar 

  16. Spinillo A, Bernuzzi AM, Cevini C, et al.: The relationship of bacterial vaginosis, Candida and Trichomonas infection to symptomatic vaginitis in postmenopausal women attending a vaginitis clinic. Maturitas 1997, 27:253–260.

    Article  PubMed  CAS  Google Scholar 

  17. Sharma R, Pickering J, McCormack WM: Trichomoniasis in a postmenopausal woman cured after discontinuation of estrogen replacement therapy. Sex Transm Dis 1997, 24:543–545.

    Article  PubMed  CAS  Google Scholar 

  18. Sobel JD, Faro S, Force RW, et al.: Vulvovaginal candidiasis: Epidemiologic, diagnostic, and therapeutic considerations. Am J Obstet Gynecol 1998, 178:203–211.

    Article  PubMed  CAS  Google Scholar 

  19. Nachtigall LE: Clinical trial of the estradiol vaginal ring in the U.S. Maturitas 1995, 22(Suppl):S43–S47.

    Article  PubMed  CAS  Google Scholar 

  20. Tobin J, Harindra V: Atrophic vulvovaginitis in women aged 50 years and above, both current and non-users of hormone replacement therapy, attending a genitourinary medicine clinic. J Fam Plann Reprod Health Care 2002, 28:135–136.

    Article  PubMed  Google Scholar 

  21. Ventolini G, Baggish M: Post-menopausal recurrent vulvovaginal candidiasis: Effect of hysterectomy on response to treatment, type of colonization and recurrence rates post-treatment. Maturitas 2005, 51:294–298.

    Article  PubMed  Google Scholar 

  22. Sobel JD, Chaim W, Leaman D: Recurrent vulvovaginal candidiasis associated with long-term tamoxifen treatment in postmenopausal women. Obstet Gynecol 1996, 88:704–706.

    Article  PubMed  CAS  Google Scholar 

  23. Cauci S, Driussi S, De Santo D, et al.: Prevalence of bacterial vaginosis and vaginal flora changes in peri-and postmenopausal women. J Clin Microbiol 2002, 40:2147–2152.

    Article  PubMed  Google Scholar 

  24. Sobel JD: Desquamative inflammatory vaginitis: a new subgroup of purulent vaginitis responsive to topical 2% clindamycin therapy. Am J Obstet Gynecol 1994, 171:1215–1220.

    PubMed  CAS  Google Scholar 

  25. Murphy R, Edwards L: Desquamative inflammatory vaginitis. Br J Dermatol 2001, 145:74.

    Google Scholar 

  26. Sobel JD: Nontrichomonal purulent vaginitis: Clinical approach. Cur Infect Dis Reports 2000, 2:501–505.

    Article  Google Scholar 

  27. Funaro D: Lichen sclerosus: A review and practical approach. Dermatol Ther 2004, 17:28–37.

    Article  PubMed  Google Scholar 

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Correspondence to Paul Nyirjesy.

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Nyirjesy, P. Postmenopausal vaginitis. Curr Infect Dis Rep 9, 480–484 (2007). https://doi.org/10.1007/s11908-007-0073-5

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