Abstract
Long-term mortality following severe sepsis is high, and fewer than half of patients who experience severe sepsis are alive at 1 year. Mechanisms underlying increased long-term mortality remain poorly understood. Animal and human studies suggest that abnormalities of the innate immune system may contribute to increased long-term mortality. This review article examines the epidemiology and potential mechanisms underlying long-term outcomes from sepsis and challenges to conducting long-term outcome studies in the critically ill.
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Yende, S., Angus, D.C. Long-term outcomes from sepsis. Curr Infect Dis Rep 9, 382–386 (2007). https://doi.org/10.1007/s11908-007-0059-3
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DOI: https://doi.org/10.1007/s11908-007-0059-3