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Incorporation of Novel Vascular Measures into Clinical Management: Recent Insights from the Framingham Heart Study

  • Blood Pressure Monitoring and Management (John Cockcroft, Section Editor)
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Abstract

Purpose of Review

The review discusses evidence from the Framingham Heart Study that supports the assessment and utility of novel vascular and blood pressure measures to inform clinical management of blood pressure–related cardiovascular disease.

Recent Findings

Recent Framingham Heart Study investigations provide new insights into the associations of novel and traditional vascular and blood pressure measures, such as measures of aortic stiffness, components of blood pressure waves, and orthostatic change in blood pressure, with cardiovascular disease events and brain structure and function. Novel vascular measures provide opportunities for additional investigation and potential development of new interventions that are more precisely targeted at underlying pathophysiology.

Summary

Inclusion of novel vascular measures should be considered in clinical practice to screen for early, subclinical disease and to stratify high-risk individuals for targeted therapies.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Biology Department, Vassar College, 124 Raymond Ave., Box 70, Poughkeepsie, NY, 12604, USA

    Leroy L. Cooper

  2. Cardiovascular Engineering, Inc., 1 Edgewater Drive, Suite 201A, Norwood, MA, 02062, USA

    Gary F. Mitchell

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Dr. Mitchell reports grants from National Institutes of Health and from Novartis, is a consultant to Merck and Servier, and is Owner and Employee of Cardiovascular Engineering, Inc. Dr. Cooper declares no conflict of interest relevant to this manuscript.

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Cooper, L.L., Mitchell, G.F. Incorporation of Novel Vascular Measures into Clinical Management: Recent Insights from the Framingham Heart Study. Curr Hypertens Rep 21, 19 (2019). https://doi.org/10.1007/s11906-019-0919-x

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