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Hypertension, Blood Pressure Variability, and Target Organ Lesion

  • Pathogenesis of Hypertension (W Elliott and R Santos, Section Editors)
  • Published:
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Abstract

Hypertensive patients have a higher risk of developing health complications, particularly cardiovascular (CV) events, than individuals with normal blood pressure (BP). Severity of complications depends on the magnitude of BP elevation and other CV risk factors associated with the target organ damage. Therefore, BP control and management of organ damage may contribute to reduce this risk. BP variability (BPV) has been considered a physiological marker of autonomic nervous system control and may be implicated in increased CV risk in hypertension. This review will present some evidence relating BPV and target organ damage in hypertension in clinical and experimental settings.

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Authors and Affiliations

  1. Hypertension Unit, Heart Institute (InCor), School of Medicine, University of Sao Paulo, Av. Dr. Enéas de Carvalho Aguiar, 44, 05403-900, São Paulo, SP, Brazil

    Maria-Cláudia Irigoyen, Fernando dos Santos & Fernanda Marciano Consolim-Colombo

  2. Laboratory of Translational Physiology, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil

    Kátia De Angelis & Fernanda Marciano Consolim-Colombo

  3. Instituto de Cardiologia do Rio Grande do Sul/ Fundação Universitária de Cardiologia (IC/FUC), Porto Alegre, RS, Brazil

    Daniela R. Dartora

  4. Faculty of Physical Education, University of Campinas (UNICAMP), Campinas, SP, Brazil

    Bruno Rodrigues

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  1. Maria-Cláudia Irigoyen
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  2. Kátia De Angelis
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  3. Fernando dos Santos
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Correspondence to Maria-Cláudia Irigoyen.

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This article is part of the Topical Collection on Pathogenesis of Hypertension

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Irigoyen, MC., De Angelis, K., dos Santos, F. et al. Hypertension, Blood Pressure Variability, and Target Organ Lesion. Curr Hypertens Rep 18, 31 (2016). https://doi.org/10.1007/s11906-016-0642-9

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