Abstract
Chronic kidney disease (CKD) affects approximately 20 million adults in the United States. Patients with CKD have an increased risk of cardiovascular (CV) disease. Ambulatory blood pressure monitoring (ABPM) provides superior BP measurements when compared to office BP measurements in normotensive, hypertensive and CKD patients. ABPM measurements are often abnormal in CKD, with CKD patients frequently showing an altered circadian rhythm with an increased rate of non-dipping and reverse dipping. The prevalence of non-dippers and reverse-dippers increases progressively as stage of CKD progresses. ABPM has been shown to be a better tool for predicting CV risk, CKD progression, end stage renal disease (ESRD) or death than office-based pressures. ABPM is also additive and adds prognostic value for predicting CKD and CV outcomes when added to estimated glomerular filtration rate (eGFR). Although ABPM is time consuming, it is worth considering, as the data demonstrates that information from ABPM can potentially impact future CV and renal outcomes in patients with CKD.
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Conflict of Interest
Debbie L. Cohen declares that she has no conflict of interest.
Yonghong Huan declares that he has no conflict of interest.
Raymond R. Townsend has received payment for consulting from AHRQ and GlaxoSmithKline, has received payment for serving as a board member for Medtronic and Merck, has received a grant from NIDDK, and has received royalties from UpToDate.
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Cohen, D.L., Huan, Y. & Townsend, R.R. Ambulatory Blood Pressure in Chronic Kidney Disease. Curr Hypertens Rep 15, 160–166 (2013). https://doi.org/10.1007/s11906-013-0339-2
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DOI: https://doi.org/10.1007/s11906-013-0339-2