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Novel Antihypertensive Therapies: Renal Sympathetic Nerve Ablation and Carotid Baroreceptor Stimulation

  • Special Situations in the Management of Hypertension (T Kotchen, Section Editor)
  • Published:
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Abstract

Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.

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Disclosure

G. Grassi: payment for lectures, including service on speakers bureaus from Medtronic; G. Seravalle: none; G. Brambilla: none; M. Bombelli: none; R. Dell'Oro: none; E. Gronda: research support from CVRx; G. Mancia: payment for lectures, including service on speakers bureaus from Medtronic.

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Authors and Affiliations

  1. Clinica Medica, Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Via Pergolesi 33, 20052, Monza, MI, Italy

    Guido Grassi, Gino Seravalle, Gianmaria Brambilla, Michele Bombelli, Raffaella Dell’Oro & Giuseppe Mancia

  2. Istituto di Ricerca e Cura a Carattere Scientifico Multimedica, Sesto San Giovanni, Milan, Italy

    Guido Grassi & Edoardo Gronda

  3. Clinica Medica, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20052, Monza, MI, Italy

    Guido Grassi

Authors
  1. Guido Grassi
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  2. Gino Seravalle
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  3. Gianmaria Brambilla
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  4. Michele Bombelli
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  5. Raffaella Dell’Oro
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  6. Edoardo Gronda
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  7. Giuseppe Mancia
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Correspondence to Guido Grassi.

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Grassi, G., Seravalle, G., Brambilla, G. et al. Novel Antihypertensive Therapies: Renal Sympathetic Nerve Ablation and Carotid Baroreceptor Stimulation. Curr Hypertens Rep 14, 567–572 (2012). https://doi.org/10.1007/s11906-012-0312-5

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  • DOI: https://doi.org/10.1007/s11906-012-0312-5

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