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HIV Prevention Interventions for Adolescents

  • The Science of Prevention (JD Stekler and JM Baeten, Section Editors)
  • Published:
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Abstract

Purpose of Review

The goal of this paper is to review recent data on biomedical, behavioral, and structural HIV prevention interventions for adolescents and young adults.

Recent Findings

While it is accepted that HIV prevention interventions must take an integrated approach to achieve maximum effectiveness, to date, there have been limited, rigorously evaluated combination prevention interventions for adolescents. There are currently a range of effective biomedical, behavioral, and structural approaches that can be integrated into prevention packages to address the prevention needs of adolescents, including oral PrEP, male circumcision, rapid HIV testing, numerous behavioral interventions, and structural interventions such as cash transfers and community mobilization to address gender-based violence.

Summary

There is still a need for rigorously evaluated, innovative combination prevention packages for adolescents. Prevention approaches must take into account the context of young people’s lives and address the multiple levels of influence on their lives including parents, partners, and communities.

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References

  1. WHO, Health for the World’s Adolescents: a second chance in the second decade, World Health Organization, Geneva, 2014.

  2. Dellar RC, Dlamini S, Karim QA. Adolescent girls and young women: key populations for HIV epidemic control. J Int AIDS Soc. 2015;19:408. https://doi.org/10.7448/IAS.18.2.19408.

    Article  Google Scholar 

  3. Children and AIDS. Statistical Update. UNICEF December 2017

  4. Youth Risk Behavior Surveillance Survey. 2015. https://www.cdc.gov/healthyyouth/data/yrbs/index.htm

  5. Geier CF. Adolescent cognitive control and reward processing: implications for risk taking and substance use. Horm Behav. 2013;64(2):333–42.

    Article  PubMed  Google Scholar 

  6. Smith AR, Chein J, Steinberg L. Impact of socio-emotional context, brain development, and pubertal maturation on adolescent risk-taking. Horm Behav. 2013;64(2):323–32.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Romer D. Adolescent risk taking, impulsivity, and brain development: implications for prevention. Dev Psychobiol. 2010;52(3):263–76.

    PubMed  PubMed Central  Google Scholar 

  8. Hawkins K, Price N, Mussa F. Milking the cow: young women’s construction of identity and risk in age-disparate transactional sexual relationships in Maputo, Mozambique. Glob Public Health. 2009;4(2):169–82. https://doi.org/10.1080/17441690701589813.

    Article  PubMed  CAS  Google Scholar 

  9. Hallett TB, Gregson S, Lewis JJ, Lopman BA, Garnett GP. Behaviour change in generalized HIV epidemics: impact of reducing cross-generational sex and delaying age at sexual debut. Sex Transm Infect. 2007;83(Suppl 1):i50–4.

    Article  PubMed  Google Scholar 

  10. Lane T, Osmand T, Marr A, Shade SB, Dunkle K, Sandfort T, et al. The Mpumalanga Men’s Study (MPMS): results of a baseline biological and behavioral HIV surveillance survey in two MSM communities in South Africa. PLoS One. 2014;9(11):e111063.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  11. Kubicek K, McNeeley M, Collins S. “Same-sex relationship in a straight world” individual and societal influences on power and control in young men’s relationships. J Interpersonal Violence 2014:0886260514532527

  12. Jewkes RK, Dunkle K, Nduna M, Shai N. Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study. Lancet. 2010;376(9734):41–8. https://doi.org/10.1016/S0140-6736(10)60548-X.

    Article  PubMed  Google Scholar 

  13. Campbell JC, Baty ML, Ghandour RM, Stockman JK, Francisco L, Wagman J. The intersection of intimate partner violence against women and HIV/AIDS: a review. Int J Inj Control Saf Promot. 2008;15(4):221–31. https://doi.org/10.1080/17457300802423224.

    Article  CAS  Google Scholar 

  14. Jeffries WL, Greene KM, Paz-Bailey G, McCree DH, Scales L, Dunville R, et al. Determinants of HIV incidence disparities among young and older men who have sex with men in the United States. AIDS Behav. 2018;9:1–5.

    CAS  Google Scholar 

  15. Casey BJ, Jones RM, Hare TA. The adolescent brain. Ann N Y Acad Sci. 2008;1124:111–26.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  16. Walensky RP. Combination HIV prevention: the value and interpretation of mathematical models. Current HIV/AIDS Reports. 2013;10(3):195–8.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Pettifor A, Nguyen NL, Celum C, Cowan FM, Go V, Hightow-Weidman L. Tailored combination prevention packages and PrEP for young key populations. J Int AIDS Soc. 2015;18(2S1).

  18. Celum C, Baeten JM, Hughes JP, Barnabas R, Liu A, Van Rooyen H, et al. Integrated strategies for combination HIV prevention: principles and examples for men who have sex with men in the Americas and heterosexual African populations. JAIDS (1999). 2013;63(0 2):S213.

    Google Scholar 

  19. DiClemente RJ, Jackson JM. Towards an integrated framework for accelerating the end of the global HIV epidemic among young people. Sex Educ. 2014;14(5):609–21.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Bekker LG, Johnson L, Wallace M, Hosek S. Building our youth for the future. J Int AIDS Soc. 2015;18(2S1).

  21. Wong V, Murray KR, Phelps BR, Vermund SH, McCarraherb DR. Adolescents, young people, and the 90–90–90 goals: a call to improve HIV testing and linkage to treatment. AIDS. 2017;31(Suppl 3):S191–4. Published online 2017 Jul 1. https://doi.org/10.1097/QAD.0000000000001539.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Brown K, Williams DB, Kinchen S, et al. Status of HIV epidemic control among adolescent girls and young women aged 15–24 years — seven African Countries, 2015–2017. MMWR Morb Mortal Wkly Rep. 2018;67:29–32. https://doi.org/10.15585/mmwr.mm6701a6.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Johnson CC, Kennedy C, Fonner V, Siegfried N, Figueroa C, Dalal S, et al. Examining the effects of HIV self-testing compared to standard HIV testing services: a systematic review and meta-analysis. J Int AIDS Soc. 2017;20(1):21594. https://doi.org/10.7448/IAS.20.1.21594.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Zanolini A, Chipungu J, Vinikoor MJ, Bosomprah S, Mafwenko M, Holmes CB, et al. HIV self-testing in Lusaka Province, Zambia: acceptability, comprehension of testing instructions, and individual preferences for self-test kit distribution in a population-based sample of adolescents and adults. AIDS Res Hum Retrovir. 2018;34(3):254–60. https://doi.org/10.1089/AID.2017.0156.

    Article  PubMed  CAS  Google Scholar 

  25. Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587–99.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  26. Baeten JM, Donnell D, Ndase P, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367(5):399–410.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  27. Thigpen MC, Kebaabetswe PM, Paxton LA, et al. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. N Engl J Med. 2012;367(5):423–34.

    Article  PubMed  CAS  Google Scholar 

  28. McCormack S, Dunn DT, Desai M, Dolling DI, Gafos M, Gilson R, et al. Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial. Lancet. 2016;387(10013):53–60.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Van Damme L, Corneli A, Ahmed K, et al. Preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2012;367(5):411–22.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  30. Marrazzo JM, Ramjee G, Richardson BA, Gomez K, Mgodi N, Nair G, et al. Tenofovir-based preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2015;372(6):509–18.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  31. Hosek SG, Landovitz RJ, Kapogiannis B, Siberry GK, Rudy B, Rutledge B, et al. Safety and feasibility of antiretroviral preexposure prophylaxis for adolescent men who have sex with men aged 15 to 17 years in the United States. JAMA Pediatr. 2017;171(11):1063–71.

    Article  PubMed  PubMed Central  Google Scholar 

  32. K. Gill, J. Dietrich, G. Gray, T. Pidwell, F. Kayamba, T. Bennie, L. Myer, L. Johnson, H. Spiegel, C. Slack, V. Elharrar, A. Strode, J. Rooney, L.-G. Bekker. Pluspills: an open label, safety and feasibility study of oral pre-exposure prophylaxis (PrEP) in 15-19 year old adolescents in two sites in South Africa. Paper presented at IAS 2017; Paris, France.

  33. Centers for Disease Control and Prevention (2014). Clinical guidelines for the use of pre-exposure prophylaxis to prevent HIV.

  34. WHO (2015). Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV.

  35. Cite FDA approval of PrEP for adolescents

  36. Digolo L, Ochieng C, Ngunjiri A, Kiragu M, Kyongo J, Otioso L, Mukoma W. Uptake of and Retention on HIV Pre Exposure Prophylaxis among adolescent girls and young women in Kenya. 8th International Workshop on Women and HIV, Boston, March 2–32,018.

  37. Morgan E, Ryan DT, Newcomb ME, Mustanski B. High rate of discontinuation may diminish PrEP coverage among young men who have sex with men. AIDS Behav. 2018;4:1–4.

    Google Scholar 

  38. HPTN 083: https://www.hptn.org/research/studies/hptn083

  39. HPTN 084: https://www.hptn.org/research/studies/hptn084

  40. Biello KB, Hosek S, Drucker MT, Belzer M, Mimiaga MJ, Marrow E, et al. Preferences for injectable PrEP among young US cisgender men and transgender women and men who have sex with men. Arch Sex Behav. 2017;19:1–7.

    Google Scholar 

  41. Minnis AM, Roberts ST, Agot K, Weinrib R, Ahmed K, Manenzhe K, et al. Young women’s ratings of three placebo multipurpose prevention technologies for HIV and pregnancy prevention in a randomized, cross-over study in Kenya and South Africa. AIDS Behav. 2018;20:1–2.

    Google Scholar 

  42. Abdool Karim Q, Abdool Karim SS, Frohlich JA, Grobler AC, Baxter C, Mansoor LE, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010:1168–74.

  43. Baeten JM, Palanee-Phillips T, Brown ER, Schwartz K, Soto-Torres LE, Govender V, et al. Use of a vaginal ring containing dapivirine for HIV-1 prevention in women. N Engl J Med. 2016.

  44. Nel A, van Niekerk N, Kapiga S, Bekker LG, Gama C, Gill K, et al. Safety and efficacy of a dapivirine vaginal ring for HIV prevention in women. N Engl J Med. 2016;375(22):2133–43.

    Article  PubMed  CAS  Google Scholar 

  45. McGowan I, Hoesley C, Cranston RD, Andrew P, Janocko L, Dai JY, et al. A Phase 1 randomised, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007). PLoS One. 2013;8(4):e60147.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  46. Cranston RD, Lama JR, Richardson BA, Carballo-Diéguez A, Ayudhya RP, Liu K, et al. MTN-017: A rectal phase 2 extended safety and acceptability study of tenofovir reduced-glycerin 1% gel. Clin Infect Dis. 2016:ciw832.

  47. Auvert B, Tajaard D, Lagarde E, Sobngwi-Tambekou J, Sitta R, Puren A. Randomised, controlled intervention of male circumcision for reduced HIV infection risk: the ANRS 1265 trial. PLoS Med. 2005;3(5):e226.

    Article  Google Scholar 

  48. Bailey RC, Moses S, Parker CB, Agot K, Maclean I, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet. 2007;369:643–56.

    Article  PubMed  Google Scholar 

  49. Gray RH, Kigozi G, Serwadda D, Makumbi F, Watya S, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet. 2007;369:657–66.

    Article  PubMed  Google Scholar 

  50. World Health Organization/Joint United Nations Programme on HIV/AIDS. Joint strategic action framework to accelerate the scale-up of voluntary medical male circumcision for HIV prevention in Eastern and Southern Africa, 2012–2016. Geneva, Switzerland: WHO/UNAIDS, 2011

  51. World Health Organization. Progress Brief: Voluntary Medical Male Circumcision for HIV Prevention in 14 Priority Countries in Eastern and Southern Africa. Geneva, July 2017.

  52. Njeuhmeli E, Opuni M, Schnure M, Tchuenche M, Stegman P, Gold E, et al. Scaling up voluntary medical male circumcision for human immunodeficiency virus prevention for adolescents and young adult men: a modeling analysis of implementation and impact in selected countries. Clin Infect Dis. 2018;66(suppl_3):S166–72.

    Article  PubMed  Google Scholar 

  53. Kaufman MR, Patel EU, Dam KH, Packman ZR, Van Lith LM, Hatzold K, et al. Counseling received by adolescents undergoing voluntary medical male circumcision: moving toward age-equitable comprehensive human immunodeficiency virus prevention measures. Clin Infect Dis. 2018;66(suppl_3):S213–20.

    Article  PubMed  PubMed Central  Google Scholar 

  54. Hergenrather KC, Emmanuel D, Durant S, Rhodes SD. Enhancing HIV prevention among young men who have sex with men: a systematic review of HIV behavioral interventions for young gay and bisexual men. AIDS Educ Prev. 2016;28(3):252–71.

    Article  PubMed  Google Scholar 

  55. Mwale M, Muula AS. Systematic review: a review of adolescent behavior change interventions [BCI] and their effectiveness in HIV and AIDS prevention in sub-Saharan Africa. BMC Public Health. 2017;17(1):718.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  56. Córdova D, Lua FM, Ovadje L, Hong E, Castillo B, Salas-Wright CP. Randomized controlled trials of technology-based HIV/STI and drug abuse preventive interventions for African American and Hispanic Youth: systematic review. JMIR Public Health Surveill. 2017;3(4).

  57. Garofalo R, Kuhns LM, Reisner SL, Biello K, Mimiaga MJ. Efficacy of an empowerment-based, group-delivered HIV prevention intervention for young transgender women: the Project LifeSkills randomized clinical trial. JAMA Pediatr. 2018.

  58. Hightow-Weidman L, LeGrand S, Simmons R, Egger K, Choi SK. and Muessig. HealthMpowerment: Effects of a mobile phone-optimized, internet-based intervention on condomless anal intercourse among young black men who have sex with men and transgender women. Presented at IAS 2017; Paris. France.

  59. Bauermeister JA, Muessig KE, LeGrand S, Flores DD, Choi SK, Dong W, et al. HIV and sexuality stigma reduction through engagement in online forums: results from the HealthMPowerment intervention. AIDS Behav. 2018:1–1.

  60. Bretz F, Koenig F, Brannath W, Glimm E, Posch M. Adaptive designs for confirmatory clinical trials. Stat Med. 2009;28(8):1181–217.

    Article  PubMed  Google Scholar 

  61. Fitts DA. Improved stopping rules for the design of efficient small-sample experiments in biomedical and biobehavioral research. Behav Res Methods. 2010;42(1):3–22.

    Article  PubMed  Google Scholar 

  62. Sullivan PS, Carballo-Diéguez A, Coates T, Goodreau SM, McGowan I, Sanders EJ, et al. Successes and challenges of HIV prevention in men who have sex with men. Lancet. 2012;380(9839):388–99.

    Article  PubMed  PubMed Central  Google Scholar 

  63. Hosek S, Siberry G, Bell M, Lally M, Kapogiannis B, Green K, et al. Project PrEPare (ATN082): the acceptability and feasibility of an HIV pre-exposure prophylaxis (PrEP) trial with young men who have sex with men (YMSM). J Acquir Immune Defic Syndr. 2013;62(4).

  64. Hosek SG, Green KR, Siberry G, Lally M, Balthazar C, Serrano PA, et al. Integrating behavioral HIV interventions into biomedical prevention trials with youth: lessons from Chicago’s Project PrEPare. Journal of HIV/AIDS & Social Services. 2013;12(3–4):333–48.

    Article  Google Scholar 

  65. Hosek SG, Rudy B, Landovitz R, Kapogiannis B, Siberry G, Rutledge B, Liu N, Brothers J, Mulligan K, Zimet G, Lally M. An HIV preexposure prophylaxis demonstration project and safety study for young MSM. JAIDS (1999). 201774(1):21–9.

  66. Pettifor A, MacPhail C, Hughes JP, Selin A, Wang J, Gómez-Olivé FX, et al. The effect of a conditional cash transfer on HIV incidence in young women in rural South Africa (HPTN 068): a phase 3, randomised controlled trial. Lancet Glob Health. 2016;4(12):e978–88.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Stoner MC, Pettifor A, Edwards JK, Aiello AE, Halpern CT, Julien A, et al. The effect of school attendance and school dropout on incident HIV and HSV-2 among young women in rural South Africa enrolled in HPTN 068. AIDS. 2017;31(15):2127–34.

    Article  PubMed  PubMed Central  Google Scholar 

  68. Abdool Karim Q, Leask K, Kharsany A, et al. Impact of conditional cash incentives on HSV-2 and HIV prevention in rural South African high school students: results of CAPRISA 007 cluster randomized trial; International AIDS Conference; Vancouver, Canada. July 19–22, 2015; TUAC0101LB.

  69. Baird SJ, Garfein RS, McIntosh CT, Özler B. Effect of a cash transfer programme for schooling on prevalence of HIV and herpes simplex type 2 in Malawi: a cluster randomised trial. Lancet. 2012;379(9823):1320–9.

    Article  PubMed  Google Scholar 

  70. Cluver L, Boyes M, Orkin M, Pantelic M, Molwena T, Sherr L. Child-focused state cash transfers and adolescent risk of HIV infection in South Africa: a propensity-score-matched case-control study. Lancet Glob Health. 2013;1(6):e362–70.

    Article  PubMed  Google Scholar 

  71. Handa S, Halpern CT, Pettifor A, Thirumurthy H. The government of Kenya’s cash transfer program reduces the risk of sexual debut among young people age 15-25. PLoS One. 2014;9(1):e85473.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  72. Cluver LD, Orkin FM, Boyes ME, Sherr L. Cash plus care: social protection cumulatively mitigates HIV-risk behaviour among adolescents in South Africa. AIDS. 2014;28:S389–97.

    Article  PubMed  Google Scholar 

  73. Roelen, K, Devereux, S, Abdulai, A, Martorano, B, Palermo, T, and Ragno, LP (2017). How to make “cash plus” work: linking cash transfers to services and sectors, Innocenti Working Paper 2017–10, UNICEF Office of Research, Florence.

  74. Stoebenau K, Heise L, Wamoyi J, Bobrova N. Revisiting the understanding of “transactional sex” in sub-Saharan Africa: a review and synthesis of the literature. Soc Sci Med. 2016;168:186–97.

    Article  PubMed  Google Scholar 

  75. Ranganathan M, MacPhail C, Pettifor A, Kahn K, Khoza N, Twine R, et al. Young women’s perceptions of transactional sex and sexual agency: a qualitative study in the context of rural South Africa. BMC Public Health. 2017;17(1):666.

    Article  PubMed  PubMed Central  Google Scholar 

  76. Mojola SA. Material girls and material love: consuming femininity and the contradictions of post-girl power among Kenyan schoolgirls. Continuum. 2015;29(2):218–29.

    Article  PubMed  Google Scholar 

  77. Shamu S, Gevers A, Mahlangu BP, Shai PNJ, Chirwa ED, Jewkes RK. Prevalence and risk factors for intimate partner violence among grade 8 learners in urban South Africa: baseline analysis from the Skhokho supporting success cluster randomised controlled trial. Int Health. 2016;8(1):18–26. https://doi.org/10.1093/inthealth/ihv068.

    Article  PubMed  Google Scholar 

  78. Russell M, Cupp PK, Jwkes RK, Gevers A, Mathews C, LeFleur-Bellerose C, et al. Intimate Partner Violence among Adolescents in Cape Town, South. Africa. 2014;15(3):283–95. https://doi.org/10.1002/ar.20849.3D.

    Article  Google Scholar 

  79. Roberts ST, Haberer J, Celum C, Mugo N, Ware NC, Cohen CR, et al. Intimate partner violence and adherence to HIV pre-exposure prophylaxis (PrEP) in African women in HIV serodiscordant relationships: a prospective cohort study. JAIDS. 2016;73(3):313.

    PubMed  Google Scholar 

  80. Jewkes R, Nduna M, Levin J, Jama N, Dunkle K, Puren A, et al. Impact of stepping stones on incidence of HIV and HSV-2 and sexual behaviour in rural South Africa: cluster randomised controlled trial. BMJ. 2008;337:a506.

    Article  PubMed  PubMed Central  Google Scholar 

  81. Pronyk PM, Hargreaves JR, Kim JC, Morison LA, Phetla G, Watts C, et al. Effect of a structural intervention for the prevention of intimate-partner violence and HIV in rural South Africa: a cluster randomised trial. Lancet. 2006;368(9551):1973–83.

    Article  PubMed  Google Scholar 

  82. Abramsky T, Devries K, Kiss L, Nakuti J, Kyegombe N, Starmann E, et al. Findings from the SASA! Study: a cluster randomized controlled trial to assess the impact of a community mobilization intervention to prevent violence against women and reduce HIV risk in Kampala, Uganda. BMC Med. 2014;12(1):122.

    Article  PubMed  PubMed Central  Google Scholar 

  83. Abramsky T, Devries KM, Michau L, Nakuti J, Musuya T, Kiss L, et al. Ecological pathways to prevention: How does the SASA! community mobilisation model work to prevent physical intimate partner violence against women? BMC Public Health. 2016;16(1):339.

    Article  PubMed  PubMed Central  Google Scholar 

  84. Wagman JA, Gray RH, Campbell JC, Thoma M, Ndyanabo A, Ssekasanvu J, et al. Effectiveness of an integrated intimate partner violence and HIV prevention intervention in Rakai, Uganda: analysis of an intervention in an existing cluster randomised cohort. Lancet Glob Health. 2015;3(1):e23–33.

    Article  PubMed  Google Scholar 

  85. Hume M, Lewis LL, Nelson RM. Meeting the goal of concurrent adolescent and adult licensure of HIV prevention and treatment strategies. J Med Ethics. 2017.

  86. Bekker LG, Slack C, Lee S, Shah S, Kapogiannis B. Ethical issues in adolescent HIV research in resource-limited countries. JAIDS. 2014;65:S24–8.

    PubMed  Google Scholar 

  87. Shah SK, Allison SM, Kapogiannis BG, Black R, Dawson L, Erbelding E. Advancing independent adolescent consent for participation in HIV prevention research. J Med Ethics. 2018;7:431–3.

    Article  Google Scholar 

  88. Austrian, Karen, Paul C. Hewett, Erica SolerHampejsek, Fiammetta Bozzani, Jere R. Behrman, and Jean Digitale. 2016. Adolescent girls empowerment programme: research and evaluation mid-term technical report. Lusaka: Zambia. Population Council.

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Hosek, S., Pettifor, A. HIV Prevention Interventions for Adolescents. Curr HIV/AIDS Rep 16, 120–128 (2019). https://doi.org/10.1007/s11904-019-00431-y

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