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Gastroesophageal reflux disease and irritable bowel syndrome: A common overlap syndrome

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Abstract

Gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS) are very common disorders in the general population. Symptoms of IBS are commonly encountered in GERD patients, and symptoms of GERD are not uncommon in IBS patients. GERD patients consistently report lower abdominal symptoms, which may be part of the spectrum of GERD symptoms. Alternatively, GERD and IBS may be two distinct manifestations of a similar underlying pathophysiologic process that can affect different levels of the gastrointestinal tract. Although the reason for the overlap observed between GERD and IBS remains to be elucidated, recent studies have demonstrated that GERD patients who also suffer from IBS-like symptoms perceive their GERD-related symptoms as more severe and are less likely to respond to antireflux treatment, as compared with those without IBS.

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Authors and Affiliations

  1. Neuro-Enteric Clinical Research Group, Southern Arizona VA Health Care System, GI Section (1-111G-1), 3601 S. 6th Avenue, 85723-0001, Tucson, AZ, USA

    Ronnie Fass MD

Authors
  1. Ram Dickman MD
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  2. Hussain Feroze MD
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  3. Ronnie Fass MD
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Correspondence to Ronnie Fass MD.

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Dickman, R., Feroze, H. & Fass, R. Gastroesophageal reflux disease and irritable bowel syndrome: A common overlap syndrome. Curr Gastroenterol Rep 8, 261–265 (2006). https://doi.org/10.1007/s11894-006-0045-1

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  • DOI: https://doi.org/10.1007/s11894-006-0045-1

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