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Evaluation and Management of Rectourethral Fistulas After Prostate Cancer Treatment

  • Voiding Dysfunction Evaluation (C Gomez, Section Editor)
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Abstract

Most men newly diagnosed with prostate cancer will undergo local treatment with prostatectomy, radiation, or tissue ablation. A small percentage of these men will develop a rectourethral fistula, a complicated disease that requires a multidisciplinary approach to management. Diagnosis is typically made with a careful history and physical exam with endoscopy and select imaging recommended in all patients. Fistulas resulting from prostatectomy, radiation, or tissue ablative technology are approached differently due to local tissue changes following therapy. Post-radiation and thermal ablation fistulas have a lower fistula closure rate due to the deleterious effect of the primary treatment on local tissue. It is imperative that the patient understands the complexity of treatment and sets reasonable goals for treatment.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63(1):11–30. doi:10.3322/caac.21166.

    Article  PubMed  Google Scholar 

  2. Mahmood U, Levy LB, Nguyen PL, Lee AK, Kuban DA, Hoffman KE. Current clinical presentation and treatment of localized prostate cancer in the United States. J Urol. 2014;192(6):1650–6. doi:10.1016/j.juro.2014.06.017.

    Article  PubMed  Google Scholar 

  3. Lefevre JH, Bretagnol F, Maggiori L, Alves A, Ferron M, Panis Y. Operative results and quality of life after gracilis muscle transposition for recurrent rectovaginal fistula. Dis Colon Rectum. 2009;52(7):1290–5. doi:10.1007/DCR.0b013e3181a74700.

    Article  CAS  PubMed  Google Scholar 

  4. Borchers H, Pinkawa M, Donner A, Wolter TP, Pallua N, Eble MJ, et al. Rectourethral fistula following LDR brachytherapy. Urol Int. 2009;82(3):365–6. doi:10.1159/000209374.

    Article  PubMed  Google Scholar 

  5. Mundy AR, Andrich DE. Posterior urethral complications of the treatment of prostate cancer. BJU Int. 2012;110(3):304–25. doi:10.1111/j.1464-410X.2011.10864.x.

    Article  PubMed  Google Scholar 

  6. Kimura M, Mouraviev V, Tsivian M, Mayes JM, Satoh T, Polascik TJ. Current salvage methods for recurrent prostate cancer after failure of primary radiotherapy. BJU Int. 2010;105(2):191–201. doi:10.1111/j.1464-410X.2009.08715.x.

    Article  CAS  PubMed  Google Scholar 

  7. Brandes SB, Morey AF. Advanced male urethral and genital reconstructive surgery. New York: Springer; 2013.

  8. Thomas C, Jones J, Jager W, Hampel C, Thuroff JW, Gillitzer R. Incidence, clinical symptoms and management of rectourethral fistulas after radical prostatectomy. J Urol. 2010;183(2):608–12. doi:10.1016/j.juro.2009.10.020.

    Article  PubMed  Google Scholar 

  9. Nyam DC, Pemberton JH. Management of iatrogenic rectourethral fistula. Dis Colon Rectum. 1999;42(8):994–7. discussion 7–9.

    Article  CAS  PubMed  Google Scholar 

  10. Hadley DA, Southwick A, Middleton RG. York-Mason procedure for repair of recto-urinary fistulae: a 40-year experience. BJU Int. 2012;109(7):1095–8. doi:10.1111/j.1464-410X.2011.10472.x. Large single center review of York-Mason RUF repair.

    Article  PubMed  Google Scholar 

  11. Joshi HM, Vimalachandran D, Heath RM, Rooney PS. Management of iatrogenic recto-urethral fistula by transanal rectal flap advancement. Color Dis: Off J Assoc Coloproctol Great Brit Irel. 2011;13(8):918–20. doi:10.1111/j.1463-1318.2010.02278.x.

    Article  CAS  Google Scholar 

  12. Kilpatrick FR, Thompson HR. Post-operative rectoprostatic fistula and closure by Kraske’s approach. Br J Urol. 1962;34:470–4.

    Article  CAS  PubMed  Google Scholar 

  13. Lane BR, Stein DE, Remzi FH, Strong SA, Fazio VW, Angermeier KW. Management of radiotherapy induced rectourethral fistula. J Urol. 2006;175(4):1382–7. doi:10.1016/S0022-5347(05)00687-7. discussion 7–8.

    Article  PubMed  Google Scholar 

  14. Vanni AJ, Buckley JC, Zinman LN. Management of surgical and radiation induced rectourethral fistulas with an interposition muscle flap and selective buccal mucosal onlay graft. J Urol. 2010;184(6):2400–4. doi:10.1016/j.juro.2010.08.004. Large single center review with excellent outcomes.

    Article  PubMed  Google Scholar 

  15. Linder BJ, Frank I, Dozois EJ, Elliott DS. Robotic transvesical rectourethral fistula repair after a robotic radical prostatectomy. Journal of Endourology. 2013;27(1).

  16. Hechenbleikner EM, Buckley JC, Wick EC. Acquired rectourethral fistulas in adults: a systematic review of surgical repair techniques and outcomes. Dis Colon Rectum. 2013;56(3):374–83. doi:10.1097/DCR.0b013e318274dc87.

    Article  PubMed  Google Scholar 

  17. Ryan Jr JA, Beebe HG, Gibbons RP. Gracilis muscle flap for closure of rectourethral fistula. J Urol. 1979;122(1):124–5.

    PubMed  Google Scholar 

  18. Youssef AH, Fath-Alla M, El-Kassaby AW. Perineal subcutaneous dartos pedicled flap as a new technique for repairing urethrorectal fistula. J Urol. 1999;161(5):1498–500.

    Article  CAS  PubMed  Google Scholar 

  19. Mundy AR, Andrich DE. Urorectal fistulae following the treatment of prostate cancer. BJU Int. 2011;107(8):1298–303. doi:10.1111/j.1464-410X.2010.09686.x. Review of RUF repair at single high-volume center.

    Article  PubMed  Google Scholar 

  20. Voelzke BB, McAninch JW, Breyer BN, Glass AS, Garcia-Aguilar J. Transperineal management for postoperative and radiation rectourethral fistulas. J Urol. 2013;189(3):966–71. doi:10.1016/j.juro.2012.08.238.

    Article  PubMed Central  PubMed  Google Scholar 

  21. Wood TW, Middleton RG. Single-stage transrectal transsphincteric (modified York-Mason) repair of rectourinary fistulas. Urology. 1990;35(1):27–30.

    Article  CAS  PubMed  Google Scholar 

  22. Gotto GT, Yunis LH, Vora K, Eastham JA, Scardino PT, Rabbani F. Impact of prior prostate radiation on complications after radical prostatectomy. J Urol. 2010;184(1):136–42. doi:10.1016/j.juro.2010.03.031.

    Article  PubMed  Google Scholar 

  23. Kitamura H, Tsukamoto T. Rectourinary fistula after radical prostatectomy: review of the literature for incidence, etiology, and management. Prostate Cancer. 2011;2011:629105. doi:10.1155/2011/629105.

    Article  PubMed Central  PubMed  Google Scholar 

  24. Faris SF, Milam DF, Dmochowski RR, Kaufman MR. Urinary diversions after radiation for prostate cancer: indications and treatment. Urology. 2014;84(3):702–6. doi:10.1016/j.urology.2014.04.023.

    Article  PubMed  Google Scholar 

  25. Beddy D, Poskus T, Umbreit E, Larson DW, Elliott DS, Dozois EJ. Impact of radiotherapy on surgical repair and outcome in patients with rectourethral fistula. Color Dis: Off J Assoc Coloproctol Great Brit Irel. 2013;15(12):1515–20. doi:10.1111/codi.12350.

    Article  CAS  Google Scholar 

  26. Chrouser KL, Leibovich BC, Sweat SD, Larson DW, Davis BJ, Tran NV, et al. Urinary fistulas following external radiation or permanent brachytherapy for the treatment of prostate cancer. J Urol. 2005;173(6):1953–7. doi:10.1097/01.ju.0000158041.77063.ff.

    Article  PubMed  Google Scholar 

  27. Izawa JI, Ajam K, McGuire E, Scott S, von Eschenbach AC, Skibber J, et al. Major surgery to manage definitively severe complications of salvage cryotherapy for prostate cancer. J Urol. 2000;164(6):1978–81.

    Article  CAS  PubMed  Google Scholar 

  28. Netsch C, Bach T, Gross E, Gross AJ. Rectourethral fistula after high-intensity focused ultrasound therapy for prostate cancer and its surgical management. Urology. 2011;77(4):999–1004. doi:10.1016/j.urology.2010.10.028.

    Article  PubMed  Google Scholar 

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Kirk M. Anderson, Maxx Gallegos, Ty T. Higuchi, and Brian J. Flynn declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Correspondence to Brian J. Flynn.

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This article is part of the Topical Collection on Voiding Dysfunction Evaluation

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Anderson, K.M., Gallegos, M., Higuchi, T.T. et al. Evaluation and Management of Rectourethral Fistulas After Prostate Cancer Treatment. Curr Bladder Dysfunct Rep 10, 132–137 (2015). https://doi.org/10.1007/s11884-015-0297-4

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  • DOI: https://doi.org/10.1007/s11884-015-0297-4

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