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Myocardial Viability and Revascularization: Current Understanding and Future Directions

  • Coronary Heart Disease (S. Virani and S. Naderi, Section Editors)
  • Published:
Current Atherosclerosis Reports Aims and scope Submit manuscript

Abstract

The initial observation of functional recovery in dysfunctional myocardium following revascularization led to the introduction of the concept of hibernating myocardium. Since then, the pathophysiologic basis of hibernating myocardium has been well described. Multiple imaging modalities have been utilized to prospectively detect viable myocardium and thus predict its functional recovery following revascularization. It has been hypothesized that viability imaging will be instrumental in the selection of patients with ischemic cardiomyopathy likely to benefit from revascularization. Multiple observational studies built a large body of evidence supporting this concept. However, data from prospective studies failed to substantiate utility of viability testing. This review aims to summarize the current literature and describe the role of viability imaging in current clinical practice as well as future directions.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Department of Cardiology, New York Methodist Hospital, 506 6th Street, Brooklyn, NY, 11215, USA

    Pavan Patel, Alexander Ivanov & Kumudha Ramasubbu

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  1. Pavan Patel
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  2. Alexander Ivanov
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  3. Kumudha Ramasubbu
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Correspondence to Kumudha Ramasubbu.

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Pavan Patel, Alexander Ivanov, and Kumudha Ramasubbu declare that they have no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Coronary Heart Disease

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Patel, P., Ivanov, A. & Ramasubbu, K. Myocardial Viability and Revascularization: Current Understanding and Future Directions. Curr Atheroscler Rep 18, 32 (2016). https://doi.org/10.1007/s11883-016-0582-5

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  • DOI: https://doi.org/10.1007/s11883-016-0582-5

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