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Role of Childhood Food Patterns on Adult Cardiovascular Disease Risk

  • Nutrition (JP Foreyt, Section Editor)
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Abstract

Accumulating evidence indicates that childhood nutrition plays a role in the adulthood cardiovascular health. A lifelong tracking of dietary habits, following a long-term exposure to unhealthy dietary patterns or independent effects, is a potential effect-mediating mechanism. Dietary patterns have been studied by data-driven and hypothesis-based approaches. Typically, either data-driven healthy or prudent childhood dietary patterns have been characterized and found to be associated with lower adulthood cardiovascular disease (CVD) risk in the published cohort studies. With regard to the individual food groups or food quality indices, intakes particularly of vegetables and fruits (or fiber indicating plant food intake) and polyunsaturated fatty acids have shown protective effects. The evidence which could confirm the long-term healthiness of a hypothesis-based Mediterranean diet is limited, requiring further investigation. Overall, the recent literature strengthens the view that a healthy childhood diet is associated with lowered adulthood CVD risk.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Poyrazoglu S, Bas F, Darendeliler F. Metabolic syndrome in young people. Curr Opin Endocrinol Diabetes Obes. 2014;21:56–63.

    Article  CAS  PubMed  Google Scholar 

  2. Alisi A, Carpino G, Nobili V. Paediatric nonalcoholic fatty liver disease. Curr Opin Gastroenterol. 2013;29:279–84.

    Article  CAS  PubMed  Google Scholar 

  3. Nicklas TA, Baranowski T, Cullen KW, et al. Eating patterns, dietary quality and obesity. J Am Coll Nutr. 2001;20:599–608.

  4. Osei-Assibey G, Dick S, Macdiarmid J, et al. The influence of the food environment on overweight and obesity in young children: a systematic review. BMJ Open. 2012;2.

  5. Juonala M, Viikari JS, Raitakari OT. Main findings from the prospective Cardiovascular Risk in Young Finns Study. Curr Opin Lipidol. 2013;24:57–64.

    Article  CAS  PubMed  Google Scholar 

  6. Campbell F, Conti G, Heckman JJ, et al. Early childhood investments substantially boost adult health. Science. 2014;343:1478–85.

  7. Lloyd-Jones DM, Hong Y, Labarthe D, et al. Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association’s strategic Impact Goal through 2020 and beyond. Circulation. 2010;121:586–613.

  8. Ambrosini GL, Emmett PM, Northstone K, et al. Tracking a dietary pattern associated with increased adiposity in childhood and adolescence. Obesity (Silver Spring). 2014;22:458–65.

  9. Mikkilä V, Räsänen L, Raitakari OT, et al. Consistent dietary patterns identified from childhood to adulthood: the cardiovascular risk in Young Finns Study. Br J Nutr. 2005;93:923–31.

  10. Ambrosini GL, Oddy WH, Robinson M, et al. Adolescent dietary patterns are associated with lifestyle and family psycho-social factors. Public Health Nutr. 2009;12:1807–15.

  11. Berge JM, Jin SW, Hannan P, et al. Structural and interpersonal characteristics of family meals: associations with adolescent body mass index and dietary patterns. J Acad Nutr Diet. 2013;113:816–22.

  12. Miller R, Tanofsky-Kraff M, Shomaker LB, et al. Serum leptin and loss of control eating in children and adolescents. Int J Obes (Lond). 2014;38:397–403.

  13. Lillycrop KA, Burdge GC. Epigenetic mechanisms linking early nutrition to long term health. Best Pract Res Clin Endocrinol Metab. 2012;26:667–76.

  14. Ruemmele FM, Garnier-Lengline H. Why are genetics important for nutrition? Lessons from epigenetic research. Ann Nutr Metab. 2012;60 Suppl 3:38–43.

  15. Koletzko B, Brands B, Poston L, et al. Early nutrition programming of long-term health. Proc Nutr Soc. 2012;71:371–8.

  16. Dwyer T, Sun C, Magnussen CG, et al. Cohort profile: the international childhood cardiovascular cohort (i3C) consortium. Int J Epidemiol. 2013;42:86–96.

  17. Simell O, Niinikoski H, Rönnemaa T, et al. Cohort profile: the STRIP study (Special Turku Coronary Risk Factor Intervention Project), an infancy-onset dietary and life-style intervention trial. Int J Epidemiol. 2009;38:650–5.

  18. Dorgan JF, Liu L, Barton BA, et al. Adolescent diet and metabolic syndrome in young women: results of the Dietary Intervention Study in Children (DISC) follow-up study. J Clin Endocrinol Metab. 2011;96:E1999–2008.

  19. Niinikoski H, Pahkala K, Ala-Korpela M, et al. Effect of repeated dietary counseling on serum lipoproteins from infancy to adulthood. Pediatrics. 2012;129:e704–13. This study is one of the rare dietary intervention studies provided long-term nutritional and other behavioral counselling for the growing children with reported benefits for later cardiovascular health.

  20. Jacobs Jr DR, Tapsell LC. Food, not nutrients, is the fundamental unit in nutrition. Nutr Rev. 2007;65:439–50.

  21. Kennedy ET, Ohls J, Carlson S, et al. The Healthy Eating Index: design and applications. J Am Diet Assoc. 1995;95:1103–8.

  22. Knoops KT, de Groot LC, Kromhout D, et al. Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE project. JAMA. 2004;292:1433–9.

  23. Lagiou P, Trichopoulos D, Sandin S, et al. Mediterranean dietary pattern and mortality among young women: a cohort study in Sweden. Br J Nutr. 2006;96:384–92.

  24. Aatola H, Koivistoinen T, Hutri-Kähönen N, et al. Lifetime fruit and vegetable consumption and arterial pulse wave velocity in adulthood: the Cardiovascular Risk in Young Finns Study. Circulation. 2010;122:2521–8.

  25. van de Laar RJ, Stehouwer CD, van Bussel BC, et al. Lower lifetime dietary fiber intake is associated with carotid artery stiffness: the Amsterdam Growth and Health Longitudinal Study. Am J Clin Nutr. 2012;96:14–23.

  26. Kaikkonen JE, Jula A, Mikkilä V, et al. Childhood serum cholesterol ester fatty acids are associated with blood pressure 27 y later in the Cardiovascular Risk in Young Finns Study. Am J Clin Nutr. 2012;95:1422–31. Longitudinal findings of this study propose that childhood serum cholesterol ester fraction n6 polyunsaturated fatty acid proportion is associated with lowered adulthood blood pressure.

  27. Moore LL, Bradlee ML, Singer MR, et al. Dietary Approaches to Stop Hypertension (DASH) eating pattern and risk of elevated blood pressure in adolescent girls. Br J Nutr. 2012;108:1678–85.

  28. Estruch R, Martinez-Gonzalez MA, Corella D, et al. Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann Intern Med. 2006;145:1–11.

  29. Yang Q, Yuan K, Gregg EW et al (2014) Trends and clustering of cardiovascular health metrics among U.S. adolescents 1988–2010. J Adolesc Health

  30. Raitakari OT, Juonala M, Rönnemaa T, et al. Cohort profile: the cardiovascular risk in Young Finns Study. Int J Epidemiol. 2008;37:1220–6.

  31. Laitinen TT, Pahkala K, Magnussen CG, et al. Ideal cardiovascular health in childhood and cardiometabolic outcomes in adulthood: the Cardiovascular Risk in Young Finns Study. Circulation. 2012;125:1971–8.

  32. Aatola H, Hutri-Kähönen N, Juonala M, et al. Prospective relationship of change in ideal cardiovascular health status and arterial stiffness: the Cardiovascular Risk in Young Finns Study. J Am Heart Assoc. 2014;3:e000532.

  33. Laitinen TT, Pahkala K, Venn A, et al. Childhood lifestyle and clinical determinants of adult ideal cardiovascular health: the Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Princeton Follow-up Study. Int J Cardiol. 2013;169:126–32.

  34. Jääskeläinen P, Magnussen CG, Pahkala K, et al. Childhood nutrition in predicting metabolic syndrome in adults: the cardiovascular risk in Young Finns Study. Diabetes Care. 2012;35:1937–43.

  35. Takaoka Y, Kawakami N. Fruit and vegetable consumption in adolescence and health in early adulthood: a longitudinal analysis of the statistics Canada’s National Population Health Survey. BMC Public Health. 2013;13:1206.

  36. Quick V, Wall M, Larson N, et al. Personal, behavioral and socio-environmental predictors of overweight incidence in young adults: 10-yr longitudinal findings. Int J Behav Nutr Phys Act. 2013;10:37.

  37. van de Laar RJ, Stehouwer CD, van Bussel BC, et al. Adherence to a Mediterranean dietary pattern in early life is associated with lower arterial stiffness in adulthood: the Amsterdam Growth and Health Longitudinal Study. J Intern Med. 2013;273:79–93. This study implements the hypothesis-based approach with a Mediterranean diet score and repeated measurements from childhood to adulthood, and shows a significant association with arterial stiffness in adulthood.

  38. Oranta O, Pahkala K, Ruottinen S, et al. Infancy-onset dietary counseling of low-saturated-fat diet improves insulin sensitivity in healthy adolescents 15–20 years of age: the Special Turku Coronary Risk Factor Intervention Project (STRIP) study. Diabetes Care. 2013;36:2952–9.

  39. Kaikkonen JE, Jula A, Mikkilä V, et al. Childhood serum fatty acid quality is associated with adult carotid artery intima media thickness in women but not in men. J Nutr. 2013;143:682–9.

  40. Goletzke J, Herder C, Joslowski G, et al. Habitually higher dietary glycemic index during puberty is prospectively related to increased risk markers of type 2 diabetes in younger adulthood. Diabetes Care. 2013;36:1870–6.

  41. Assmann KE, Joslowski G, Buyken AE, et al. Prospective association of protein intake during puberty with body composition in young adulthood. Obesity (Silver Spring). 2013;21:E782–9.

  42. Zheng M, Rangan A, Olsen NJ, et al. Sugar-sweetened beverages consumption in relation to changes in body fatness over 6 and 12 years among 9-year-old children: the European Youth Heart Study. Eur J Clin Nutr. 2014;68:77–83.

  43. Malik VS, Fung TT, van Dam RM, et al. Dietary patterns during adolescence and risk of type 2 diabetes in middle-aged women. Diabetes Care. 2012;35:12–8. Retrospective food consumption assessment and data-driven factor analysis have been used to identify dietary patterns among over 37000 female adolescents, now adult women. A Western dietary pattern is shown to be associated with the risk of type 2 diabetes in midlife, partly mediated by BMI.

  44. Hosking D, Danthiir V. Retrospective lifetime dietary patterns are associated with demographic and cardiovascular health variables in an older community-dwelling Australian population. Br J Nutr. 2013;110:2069–83. Data-driven cluster analysis is successfully implemented in a retrospective setting with a simplified food consumption method, and a Traditional Australian dietary pattern is shown to be protective of CVD risk factors. Methods and possible effects of socio-demographic factors are thoroughly discussed.

  45. Duffey KJ, Steffen LM, Van HL, et al. Dietary patterns matter: diet beverages and cardiometabolic risks in the longitudinal Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Clin Nutr. 2012;95:909–15.

  46. Ritchie LD, Spector P, Stevens MJ, et al. Dietary patterns in adolescence are related to adiposity in young adulthood in black and white females. J Nutr. 2007;137:399–406.

  47. Juonala M, Viikari JS, Kähönen M, et al. Life-time risk factors and progression of carotid atherosclerosis in young adults: the Cardiovascular Risk in Young Finns study. Eur Heart J. 2010;31:1745–51.

    Article  CAS  PubMed  Google Scholar 

  48. WHO Action Plan for the Global Strategy for the Prevention and Control of Noncommunicable Diseases. Geneva, Switzerland: World Health Organization, WHO Press; 2008. 2014

  49. Lim SS, Vos T, Flaxman AD, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2224–60.

  50. te Velde SJ, Twisk JW, Brug J. Tracking of fruit and vegetable consumption from adolescence into adulthood and its longitudinal association with overweight. Br J Nutr. 2007;98:431–8.

  51. Aljadani HM, Patterson A, Sibbritt D, et al. Diet quality, measured by fruit and vegetable intake, predicts weight change in young women. J Obes. 2013;2013:525161.

    Article  PubMed Central  PubMed  Google Scholar 

  52. Keys A. Diet and the epidemiology of coronary heart disease. J Am Med Assoc. 1957;164:1912–9.

  53. Panico S, Mattiello A, Panico C, et al. Mediterranean dietary pattern and chronic diseases. Cancer Treat Res. 2014;159:69–81.

    Article  PubMed  Google Scholar 

  54. Tognon G, Hebestreit A, Lanfer A, et al. Mediterranean diet, overweight and body composition in children from eight European countries: cross-sectional and prospective results from the IDEFICS study. Nutr Metab Cardiovasc Dis. 2014;24:205–13.

  55. Arriscado D, Muros JJ, Zabala M, et al. Factors associated with low adherence to a Mediterranean diet in healthy children in northern Spain. Appetite. 2014;80C:28–34.

  56. Lazarou C, Panagiotakos DB, Kouta C, et al. Dietary and other lifestyle characteristics of Cypriot school children: results from the nationwide CYKIDS study. BMC Public Health. 2009;9:147.

  57. Eckel RH, Jakicic JM, Ard JD, et al. AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;2013.

  58. Moilanen T, Räsänen L, Viikari J, et al. Fatty acid composition of serum cholesteryl esters in 3- to 18-year-old Finnish children and its relation to diet. Am J Clin Nutr. 1985;42:708–13.

  59. Kwiterovich Jr PO, Barton BA, McMahon RP, et al. Effects of diet and sexual maturation on low-density lipoprotein cholesterol during puberty: the Dietary Intervention Study in Children (DISC). Circulation. 1997;96:2526–33.

  60. Rouhani MH, Kelishadi R, Hashemipour M, et al. Glycemic index, glycemic load and childhood obesity: a systematic review. Adv Biomed Res. 2014;3:47.

  61. Garden FL, Marks GB, Simpson JM, et al. Body mass index (BMI) trajectories from birth to 11.5 years: relation to early life food intake. Nutrients. 2012;4:1382–98.

  62. Hasnain SR, Singer MR, Bradlee ML, et al. Beverage intake in early childhood and change in body fat from preschool to adolescence. Child Obes. 2014;10:42–9.

  63. Ambrosini GL, Oddy WH, Huang RC, et al. Prospective associations between sugar-sweetened beverage intakes and cardiometabolic risk factors in adolescents. Am J Clin Nutr. 2013;98:327–34.

  64. Niinikoski H, Ruottinen S. Is carbohydrate intake in the first years of life related to future risk of NCDs? Nutr Metab Cardiovasc Dis. 2012;22:770–4.

  65. Lioret S, McNaughton SA, Cameron AJ, et al. Three-year change in diet quality and associated changes in BMI among schoolchildren living in socio-economically disadvantaged neighbourhoods. Br J Nutr. 2014;112:1–9.

  66. Pala V, Lissner L, Hebestreit A, et al. Dietary patterns and longitudinal change in body mass in European children: a follow-up study on the IDEFICS multicenter cohort. Eur J Clin Nutr. 2013;67:1042–9.

  67. Golley RK, Smithers LG, Mittinty MN, et al. Diet quality of U.K. infants is associated with dietary, adiposity, cardiovascular, and cognitive outcomes measured at 7–8 years of age. J Nutr. 2013;143:1611–7.

  68. Oddy WH, Herbison CE, Jacoby P, et al. The Western dietary pattern is prospectively associated with nonalcoholic fatty liver disease in adolescence. Am J Gastroenterol. 2013;108:778–85.

  69. Ambrosini GL, Emmett PM, Northstone K, et al. Identification of a dietary pattern prospectively associated with increased adiposity during childhood and adolescence. Int J Obes (Lond). 2012;36:1299–305.

  70. Cutler GJ, Flood A, Hannan PJ, et al. Association between major patterns of dietary intake and weight status in adolescents. Br J Nutr. 2012;108:349–56.

  71. Oellingrath IM, Svendsen MV, Brantsaeter AL. Tracking of eating patterns and overweight—a follow-up study of Norwegian schoolchildren from middle childhood to early adolescence. Nutr J. 2011;10:106.

  72. Shroff MR, Perng W, Baylin A, et al. Adherence to a snacking dietary pattern and soda intake are related to the development of adiposity: a prospective study in school-age children. Public Health Nutr. 2014;17:1507–13.

  73. Pedersen AN, Kondrup J, Borsheim E. Health effects of protein intake in healthy adults: a systematic literature review. Food Nutr Res. 2013;57.

  74. Hornell A, Lagstrom H, Lande B, et al. Protein intake from 0 to 18 years of age and its relation to health: a systematic literature review for the 5th Nordic Nutrition Recommendations. Food Nutr Res. 2013;57.

  75. Krupp D, Johner SA, Kalhoff H, et al. Long-term dietary potential renal acid load during adolescence is prospectively associated with indices of nonalcoholic fatty liver disease in young women. J Nutr. 2012;142:313–9.

  76. Williams CM, Lovegrove JA, Griffin BA. Dietary patterns and cardiovascular disease. Proc Nutr Soc. 2013;72:407–11.

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Jari E. Kaikkonen, Vera Mikkilä, and Olli T. Raitakari declare that they have no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Kiinamyllynkatu 10, 20520, Turku, Finland

    Jari E. Kaikkonen, Vera Mikkilä & Olli T. Raitakari

  2. NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland

    Jari E. Kaikkonen

  3. Division of Nutrition, Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland

    Vera Mikkilä

  4. Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland

    Olli T. Raitakari

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  1. Jari E. Kaikkonen
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Correspondence to Jari E. Kaikkonen.

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Mikkilä and Kaikkonen had equal contribution (in planning and writing of this manuscript).

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Kaikkonen, J.E., Mikkilä, V. & Raitakari, O.T. Role of Childhood Food Patterns on Adult Cardiovascular Disease Risk. Curr Atheroscler Rep 16, 443 (2014). https://doi.org/10.1007/s11883-014-0443-z

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