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Environmental control for fungal allergen exposure

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Abstract

With our limited knowledge of the mold allergens, we must rely on common sense to reduce environmental exposure for patients who are allergic to mold. We understand that the first step is moisture control. Appropriate building design, keeping rainwater and ground water away from the interior, accomplishes this. In addition, the heating ventilation and air conditioning system must be appropriately designed and maintained. Functional maintenance of inside water sources such as free water from plumbing, appliances, and showers can prevent damaging leaks. Indoor humidity or water vapor must be controlled and maintained to prevent condensation on walls or in microenvironments, such as attics, bedrooms, basements, and beneath wall-to-wall carpeting. Few abatement trials have been published, but several suggest that such measures can reduce mold exposure.

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References and Recommended Reading

  1. Institute of Medicine Committee on the Assessment of Asthma and Indoor Air: Indoor dampness and asthma. In Clearing the Air: Asthma and Indoor Air Exposures. Washington DC: National Academy Press; 2000:263–297. An excellent assessment of current knowledge regarding the respiratory health effects of indoor dampness and moisture.

    Google Scholar 

  2. Brunekreef B, Dockery DW, Spiezer FE, et al.: Home dampness and respiratory morbidity in children. Am Rev Respir Dis 1989, 140:1363–1367.

    PubMed  CAS  Google Scholar 

  3. Dales RE, Miller D, McMullen E: Indoor air quality and health: validity and determinants of reported home dampness and moulds. Int J Epidemiol 1997, 26:120–124.

    Article  PubMed  CAS  Google Scholar 

  4. Gent JF, Ren P, Belager K, et al.: Levels of household mold associated with respiratory symptoms in the first year of life in a cohort at risk for asthma. Environ Health Perspect 2002, 110:A781-A786.

    Article  PubMed  Google Scholar 

  5. Pirhonen I, Nevalainen A, Husman T, Pekkanen J: Home dampness, moulds and their influence on respiratory infections and symptoms in adults in Finland. Eur Respir J 1996, 9:2618–2622.

    Article  PubMed  CAS  Google Scholar 

  6. Solomon WR, Platts-Mills TAE: Aerobiology and inhalant allergens. In Allergy Principles and Practice, edn 5. Edited by Middleton E Jr, Reed CE, Ellis EF, et al. St Louis: Mosby; 1998:367–403.

    Google Scholar 

  7. Liu D, Nazaroff WW: Particle penetration through windows. Proc Indoor Air 2002. 2002, 8:862–867.

    Google Scholar 

  8. Mosley RB, Greenwell DJ, Sparks LE, et al.: Penetration of ambient fine particles into the indoor environment. Aerosol Sci Technol 2001, 34:127–136.

    Article  CAS  Google Scholar 

  9. Garrett MH, Rayment PR, Hoper MA, et al.: Indoor airborne fungal spores, house dampness and associations with environmental factors and respiratory health in children. Clin Exp Allergy 1998, 28:459–467.

    Article  PubMed  CAS  Google Scholar 

  10. Institute of Medicine Committee on the Health Effects of Indoor Allergens: Engineering control strategies. In Allergens: Assessing and Controlling Adverse Health Effects. Washington, DC: National Academy Press; 1993:206–232.

    Google Scholar 

  11. American Thoracic Society Workshop: Achieving healthy indoor air. Am J Resp Crit Care Med 1997, 156(Suppl):44–64. A detailed description of building design and maintenance to prevent indoor dampness problems, with all appropriate references to documents.

    Google Scholar 

  12. Gravesen S, Nielsen P, Iversen R, Nielsen K: Microfungal contamination of damp buildings: examples of risk constructions and risk materials. Environ Health Perspect 1999, 107(Suppl3):505–508.

    PubMed  Google Scholar 

  13. Halonen M, Stern DA, Wright AL, et al.: Alternaria as a major allergen for asthma in children raised in a desert environment. Am J Respir Crit Care Med 1997, 155:1356–1361.

    PubMed  CAS  Google Scholar 

  14. Wood RA, Eggleston PA, Lind P, et al.: Antigenic analysis of household dust samples. Am Rev Respir Dis 1988, 137:358–363.

    PubMed  CAS  Google Scholar 

  15. Douwes J, van der Sluis B, Doekes G, et al.: Fungal extracellular polysaccharides in house dust as a marker for exposure to fungi: relations with culturable fungi, reported home dampness, and respiratory symptoms. J Allergy Clin Immunol 1999, 103:494–500.

    Article  PubMed  CAS  Google Scholar 

  16. Wickman M, Gravesen S, Nordvall L, et al.: Indoor viable dustbound microfungi in relation to residential characteristics, living habits, and symptoms in atopic and control children. J Allergy Clin Immunol 1992, 89:752–759.

    Article  PubMed  CAS  Google Scholar 

  17. Dharmage S, Bailey M, Raven J, et al.: Prevalence and residential determinants of fungi within homes in Melbourne, Australia. Clin Exp Allergy 1999, 29:1481–1489.

    Article  PubMed  CAS  Google Scholar 

  18. Burge HA, Solomon WR, Boise JR: An appraisal of impregnon as a deterrent of domestic fungus growth. J Allergy Clin Immunol 1976, 58:491–499.

    Article  PubMed  CAS  Google Scholar 

  19. Garrison RA, Robertson LD, Koehn RD, Wynn SR: Effect of heating-ventilation-air conditioning system sanitation on airborne fungal populations in residential environments. Ann Allergy 1994, 71:548–556.

    Google Scholar 

  20. Kuhn DM, Ghannoun MA: Indoor mold, toxigenic fungi and Stachybotrys chartarum: infectious disease perspective. Clin Microbiol Rev 2003, 16:144–172. This is the definitive reference on the infectious and toxic effects of mold. It is extensively referenced and deals with the very important issue of toxigenic mold. This aspect of mold biology is well publicized, and this paper provides a clear and thoughtful assessment of the evidence.

    Article  PubMed  CAS  Google Scholar 

  21. Von Essen S, Robbins RA, Thompson AB, Rennard SI: Organic dust toxic syndrome: an acute febrile reaction to organic dust exposure distinct from hypersensitivity pneumonitis. J Toxicol Clin Toxicol 1990, 28:389–342.

    Article  Google Scholar 

  22. Etzel RA, Montana E, Sorenson WG, et al.: Acute pulmonary hemorrhage in infants associated with exposure to Stachybotrys atra and other fungi. Arch Pediatr Adolesc Med 1998, 152:757–762.

    PubMed  CAS  Google Scholar 

  23. Richerson HP: Unifying concepts underlying the effect of organic dusts exposure. Am J Ind Med 1990, 17:139–142.

    PubMed  CAS  Google Scholar 

  24. Environmental Protection Agency: Clear your home of asthma triggers. No 402-F-99-005. Washington, DC: EPA; 1999.

    Google Scholar 

  25. Savilahti R, Uitti J, Laippala P, et al.: Respiratory morbidity among children following renovation of a water-damaged school. Arch Environ Health 2000, 55:405–410.

    Article  PubMed  CAS  Google Scholar 

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Eggleston, P.A. Environmental control for fungal allergen exposure. Curr Allergy Asthma Rep 3, 424–429 (2003). https://doi.org/10.1007/s11882-003-0079-5

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