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Intracavitary therapies for mesothelioma

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Opinion statement

  • The diagnosis of mesothelioma needs to be defined histologically.

  • The staging system has been recently redefined anatomically, but may not be applicable to extrapleural mesothelioma.

  • Further clinicopathologic studies need to be performed to molecularly classify the disease further, according to prognosis.

  • Intracavitary therapy has a definite role in the treatment of mesothelioma.

  • Randomized studies of intracavitary therapies are needed to define the best treatment option.

  • The role of complementary therapeutic modalities such as surgery and radiotherapy needs to be defined by randomized studies.

  • There is an urgent need to better understand the biology of mesothelioma, which may lead to more focus on molecularly relevant therapies.

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Verschraegen, C.F. Intracavitary therapies for mesothelioma. Curr. Treat. Options in Oncol. 2, 385–394 (2001). https://doi.org/10.1007/s11864-001-0043-3

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