References
Moran SM, Fitzgerald N, Pope M, Madden M, Vaughan CJ (2011) Warfarin anticoagulation: a survey of patient’s knowledge of their treatment. IJMS 180(4):819–822
Medsafe Editorial Team (2003) Miconazole—warfarin interaction reminder. Prescr Updat 24(1):12
Pemberton MN, Oliver RJ, Theaker ED (2004) Miconazole oral gel and drug interactions. Br Dent J 196(9):529–531
O’Reilly RA, Goulart DA, Kunze KL et al (1992) Mechanisms of stereoselective interactions between miconazole and racemic warfarin in human subjects. Clin Pharmacol Ther 51:656–667
Miki A, Ohtani H, Sawada Y (2011) Warfarin and miconazole oral gel interactions: analysis and therapy recommendations based on clinical data and a pharmacokinetic model. J Clin Pharm Ther 36(6):642–650
Thirion DJG, Zanetti LA (2000) Potentiation of warfarin’s hypoprothrobinaemic effect with miconazole vaginal suppositories. Pharmacotherapy 20:98–99
Devaraj A, O’Beirne JP, Veasey R, Dunk AA (2002) Interaction between warfarin and topical miconazole cream. BMJ 325(7355):77
Kovac M, Mitic G, Kovac Z (2012) Miconazole and nystatin used as topical antifungal drugs interact equally strongly with warfarin. J Clin Pharm Ther 37(1):45–48
Irish Medicines Board (2012) Drug safety 47
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Ufondu, C.C., Ferrins, P., Cushen, A. et al. Warfarin and topical miconazole: the potential for a clinically significant interaction. Ir J Med Sci 182, 153–154 (2013). https://doi.org/10.1007/s11845-012-0862-1
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DOI: https://doi.org/10.1007/s11845-012-0862-1