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Unusual paraneoplastic syndromes of breast carcinoma: a combination of cerebellar degeneration and Lambert–Eaton Myasthenic Syndrome

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Abstract

Introduction

Paraneoplastic neurological disorders are rare complications of breast carcinoma. Lambert–Eaton Myasthenic Syndrome (LEMS) is most commonly associated with small cell lung cancer. However, a combination of LEMS and subacute cerebellar degeneration as paraneoplastic syndromes is extremely rare, and has never been described in association with breast cancer.

Case

We report for the first time an unusual association of LEMS and paraneoplastic subacute cerebellar degeneration with breast carcinoma.

Conclusion

In patients with atypical LEMS, when there is no evidence of respiratory malignancy, breast cancer should be included in the differential diagnosis.

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Author information

Authors and Affiliations

  1. Department of Surgery, Cork University Hospital, Wilton, Cork, Ireland

    L. Romics Jr, P. A. Cronin, N. Relihan & H. P. Redmond

  2. Department of Neurology and Neurophysiology, Cork University Hospital, Cork, Ireland

    B. McNamara

  3. Faculty of Medicine and Health, University College Cork, Cork, Ireland

    M. E. O’Brien

Authors
  1. L. Romics Jr
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  2. B. McNamara
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  3. P. A. Cronin
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  4. M. E. O’Brien
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  5. N. Relihan
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  6. H. P. Redmond
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Corresponding author

Correspondence to L. Romics Jr.

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Romics, L., McNamara, B., Cronin, P.A. et al. Unusual paraneoplastic syndromes of breast carcinoma: a combination of cerebellar degeneration and Lambert–Eaton Myasthenic Syndrome. Ir J Med Sci 180, 569–571 (2011). https://doi.org/10.1007/s11845-008-0257-5

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  • DOI: https://doi.org/10.1007/s11845-008-0257-5

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