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Preparation of nylon-6/chitosan composites by nanospider technology and their use as candidate for antibacterial agents

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Abstract

Electrospun nylon-6/chitosan (nylon-6/Ch) nanofibers were prepared by nanospider technology. Quaternary ammonium salts as antibacterial agent were immobilized onto electrospun nylon-6/Ch nanofibers via surface modification by soaking the mat in aqueous solution of glycidyltrimethylammonium chloride (GTMAC) at room temperature overnight to give nylon-6/N-[(2-hydroxy-3-trimethylammonium)propyl] chitosan chloride (nylon-6/HTCC). The morphological, structural and thermal properties of the nylon-6/ch nanofibers were studied by field-emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), Fourier transform-infrared (FT-IR) spectroscopy, and thermogravimetric analysis (TGA). Biological screening has demonstrated the antibacterial activity of the electrospun nanofibers against Gram negative bacteria, Escherichia coli 35218, and Pseudomonas aeruginosa and Gram positive bacteria, Staphylococcus aureus 24213 among the tested microbes. Thus, the study ascertains the value of the use of electrospun nanofibers, which could be of considerable interest to the development of new antibacterial materials for biomedical applications.

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Authors and Affiliations

  1. Department of Chemistry, College of Science, King Saud University, P. O. Box 2455, Riyadh, 11451, Saudi Arabia

    Salem Slayyem Al-Deyab, Mohamed Hassan El-Newehy & Hak Yong Kim

  2. Department of Chemistry, Faculty of Science, Tanta University, Tanta, 31527, Egypt

    Mohamed Hassan El-Newehy

  3. Department of Organic Materials and Fiber Engineering, Chonbuk National University, Jeonju, 561-756, Korea

    Rajkumar Nirmala & Hak Yong Kim

  4. Department of Botany, College of Science, King Saud University, P. O. Box 2455, Riyadh, 11451, Saudi Arabia

    Ahmed Abdel-Megeed

  5. Department of Plant Protection, Faculty of Agriculture (Saba Basha), Alexandria University, Alexandria, 2153, Egypt

    Ahmed Abdel-Megeed

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  1. Salem Slayyem Al-Deyab
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  2. Mohamed Hassan El-Newehy
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  3. Rajkumar Nirmala
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  4. Ahmed Abdel-Megeed
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  5. Hak Yong Kim
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Correspondence to Mohamed Hassan El-Newehy.

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Al-Deyab, S.S., El-Newehy, M.H., Nirmala, R. et al. Preparation of nylon-6/chitosan composites by nanospider technology and their use as candidate for antibacterial agents. Korean J. Chem. Eng. 30, 422–428 (2013). https://doi.org/10.1007/s11814-012-0154-5

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  • DOI: https://doi.org/10.1007/s11814-012-0154-5

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