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Control of air leakage during pleurectomy/decortication by the ventilation and anchoring method

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Abstract

Objectives

We previously established a novel method of lung repair called the ventilation and anchoring (V/A) method. We evaluated the usefulness of the V/A method for controlling air leakage during pleurectomy/decortication (P/D).

Methods

For this study, we enrolled patients with malignant pleural mesothelioma (MPM) who planned to receive P/D. Our lung repair method involves (1) suturing lung parenchyma for an apparent injured lesion and (2) coating the lung parenchyma with fibrin glue (FG) using the V/A method. The tidal volume (TV) was measured under pressure-controlled ventilation in the ipsilateral-affected lung 10 times at the following four points: after thoracotomy, at completion of visceral pleurectomy, after suturing lung parenchyma, and 5 min after coating with FG. The primary endpoint was the mean TV (mTV) change, and the secondary endpoints were the duration of air leakage and incidence of pleurodesis.

Results

Between April 2014 and April 2016, 25 patients of the 29 consecutive patients enrolled were eligible. The mTV significantly decreased after completion of visceral pleurectomy but significantly increased after repair of the lung parenchyma, especially after coating with FG. The median duration of postoperative air leakage was 4 days (range: 2–19 days). Postoperative air leakage > 7 days was observed in 11 (44%) patients. Of these 11 patients, 6 received pleurodesis; however, no further revision was needed.

Conclusions

Significant increases in TV were observed after coating with FG via the V/A method during P/D. Coating with FG using the V/A method can contribute to a reduction in air leakage during P/D.

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Abbreviations

EPP:

Extrapleural pneumonectomy

FG:

Fibrin glue

MPM:

Malignant pleural mesothelioma

mTV:

Mean tidal volume

P/D:

Pleurectomy/decortication

PGA:

Polyglycolic acid

TV:

Tidal volume

V/A:

Ventilation–anchoring

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Acknowledgements

The authors appreciate the cooperation of the anaesthesiologist. We also thank Mrs. Risa Murata for her secretarial work.

Funding

This study was not supported by any funding.

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Authors and Affiliations

  1. Department of Thoracic Surgery, Hyogo College of Medicine, Mukogawa-cho 1-1, Nishinomiya, 6638501, Japan

    Masaki Hashimoto, Nobuyuki Kondo, Toru Nakamichi, Akifumi Nakamura, Seiji Matsumoto & Seiki Hasegawa

  2. Department of Thoracic Surgery, Itami City Hospital, Itami, Japan

    Ayumi Kuroda

  3. Department of Thoracic Surgery, Saiseikai Noe Hospital, Osaka, Japan

    Teruhisa Takuwa

Authors
  1. Masaki Hashimoto
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  2. Nobuyuki Kondo
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  3. Toru Nakamichi
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  4. Akifumi Nakamura
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  5. Ayumi Kuroda
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  6. Teruhisa Takuwa
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  7. Seiji Matsumoto
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  8. Seiki Hasegawa
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Contributions

Conceptualization, M.H, N.K, and S.H; methodology, M.H and N.K; patient recruitment, M.H, T.N, A.N, A.K, T.T, and S.M; statistical analysis, M.H; data collection, M.H, T.N, A.N, A.K, T.T, and S.M; writing—original draft preparation, M.H; writing—review and editing, N.K and S.H; supervision, S.H; project administration, M.H. All the authors have read and approved the manuscript.

Corresponding author

Correspondence to Masaki Hashimoto.

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Hashimoto, M., Kondo, N., Nakamichi, T. et al. Control of air leakage during pleurectomy/decortication by the ventilation and anchoring method. Gen Thorac Cardiovasc Surg 70, 730–734 (2022). https://doi.org/10.1007/s11748-022-01789-4

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  • DOI: https://doi.org/10.1007/s11748-022-01789-4

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