Abstract
Pulmonary sclerosing pneumocytoma (PSP) is a rare tumor and the imaging appearance is usually a well-circumscribed nodule. Herein we present the clinicopathological features of a 25-year-old female patient with a 4 cm mass in the left upper lobe. She had undergone lobectomy with lymph node dissection with an incorrect intraoperative frozen section diagnosis of adenocarcinoma and diagnosed as a PSP with lymph node metastasis on permanent sections. The 3-year follow-up of the patient is uneventful.
Similar content being viewed by others
References
Liebow AA, Hubbell DS. Sclerosing hemangioma (histiocytoma, xanthoma) of the lung. Cancer. 1956;9:53–755.
Shin SY, Kim MY, Oh SY, Lee HJ, Hong SA, Jang SJ, et al. Pulmonary sclerosing pneumocytoma of the lung: CT characteristics in a large series of a tertiary referral center. Medicine. 2015;94(4):e498.
Devouassoux-Shisheboran M, Hayashi T, Linnoila RI, Koss MN, Travis WD. A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies. TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium. Am J Surg Pathol. 2000;24:906–16.
Tanaka I, Inoue M, Matsui Y, Oritsu S, Akiyama O, Takemura T, et al. A case of pneumocytoma (so-called sclerosing hemangioma) with lymph node metastasis. Jpn J Clin Oncol. 1986;16(1):77–86.
Soo IX, Sittampalam K, Lim CH. Pulmonary sclerosing pneumocytoma with mediastinal lymph node metastasis. Asian Cardiovasc Thorac Annals. 2017;25(7–8):547–9.
Wang X, Zhang L, Wang Y, Jia X, Wang J, Zhang H. Sclerosing pneumocytoma with metastasis to the mediastinal and regional lymph nodes. Indian J Pathol Microbiol. 2018;61:407–9.
Miyagawa-Hayashino A, Tazelaar HD, Langel DJ, Colby TV. Pulmonary sclerosing hemangioma with lymph node metastases: report of 4 cases. Arch Pathol Lab Med. 2003;127(3):321–5.
Katakura H, Sato M, Tanaka F, et al. Pulmonary sclerosing hemangioma with metastasis to the mediastinal lymph node. Ann Thorac Surg. 2005;80(6):2351–3.
Kim GY, Kim J, Choi YS, Kim HJ, Ahn G, Han J. Sixteen cases of sclerosing hemangioma of the lung including unusual presentations. J Korean Med Sci. 2004;19(3):352–8.
Xu HM, Zhang G. A rare case of pulmonary sclerosing hemagioma with lymph node metastasis and review of the literature. Int J Clin Exp Pathol. 2015;8(7):8619–23.
Adachi Y, Tsuta K, Hırano Y, Tanaka J, Mınamıno K, Shımo T, et al. Pulmonary sclerosing hemangioma with lymph node metastasis: a case report and literature review. Oncol Lett. 2014;7:997–1000.
Yano M, Yamakawa Y, Kiriyama M, Hara M, Murase T. Sclerosing hemangioma with metastases to multiple nodal stations. Ann Thorac Surg. 2002;73(3):981–3.
Kim MK, Jang SJ, Kim YH, Kim SW. Bone metastasis in pulmonary sclerosing hemangioma. Korean J Intern Med. 2015;30(6):928–30.
Suzuki H, Saitoh Y, Koh E, Hoshıno H, Kase D, Kasei Y, et al. Pulmonary sclerosing hemangioma with pleural dissemination: report of a case. Surg Today. 2011;41:258–61.
Yang CH, Lee LY. Pulmonary sclerosing pneumocytoma remains a diagnostic challenge using frozen sections: a clinicopathological analysis of 59 cases. Histopathology. 2018;72:500–8.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflıct of ınterest
Gökhan Kocaman has no conflict of interest. Mustafa Bülent Yenigün has no conflict of interest. Cevriye Cansız Ersöz has no conflict of interest. Serpil Dizbay Sak has no conflict of interest. Serkan Enön has no conflict of interest.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Kocaman, G., Yenigün, M.B., Ersöz, C.C. et al. Pulmonary sclerosing pneumocytoma with mediastinal lymph node metastasis: a case report. Gen Thorac Cardiovasc Surg 69, 142–146 (2021). https://doi.org/10.1007/s11748-020-01431-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11748-020-01431-1