Abstract
A 73-year-old female was referred to our hospital in June 2000 for the evaluation of an abnormal shadow in the left upper lobe of her lung and two other shadows in the left lower lobe. A computed tomography examination revealed an ill-defined tumor with ground glass opacity in the left upper division segment, suggesting a primary lung adenocarcinoma, and two well-defined nodules in the left lower lobe, suggesting metastatic carcinomas. A transbronchial lung biopsy of the tumor in the upper division segment confirmed the presence of an adenocarcinoma but failed to provide a histological diagnosis for the nodules in the lower lobe. A partial resection of the left lower lobe using video-assisted thoracoscopy revealed granulomatous tissue with no signs of malignancy. A curative resection of the adenocarcinoma in the left upper division segment was therefore performed. Histologically, the resected specimens obtained from the left lower lobe were diagnosed as cryptococcomas. The patient was diagnosed as having a stage IA lung adenocarcinoma and two cryptococcomas. The patient is presently well and has not experienced any recurrences or relapse for 3 years since the resection.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Lewis JL, Rabinovich S. The wide spectrum of cryptococcal infections. Am J Med 1972; 53: 315–22.
Rozenbaum R, Goncalves AJ. Clinical epidemiological study of 171 cases of cryptococcosis. Clin Infect Dis 1994; 18: 369–80.
Feigin DS. Pulmonary cryptococcosis: Radiologic-pathologic correlates of its three forms. AJR Am J Roentgenol 1983; 141: 1262–72.
Kohno S, Yasuoka A, Koga H, Kaku M, Maesaki S, Tanaka K, et al. High detection rates of cryptococcal antigen in pulmonary cryptococcosis by Eiken latex agglutination test with pronase pretreatment. Mycopathologia 1993; 123: 75–9.
Ginsberg MS, Griff SK, Go BD, Yoo HH, Schwartz LH, Panicek DM. Pulmonary nodules resected at video- assisted thoracoscopic surgery: Etiology in 426 patients. Radiology 1999; 213: 277–82.
Inaba H, Nagashima Y, Ohta S, Itoh Y, Ishida I, Honda A. Three cases of resected lung cancer accompanied by cryptococcal infection (Eng abstr). Jpn J Lung Cancer 1997; 37: 401–8.
Yamamoto Y, Ohi H, Narasaki F, Hayashi T, Maesaki S, Tomono K, et al. A case of pulmonary cryptococcosis with lung cancer in a pulmonary lobe (Eng abstr). Kansenshogaku Zasshi 1999; 73: 187–90.
Fujita T, Fujino S, Inoue S, Kontani K, Sawai S, Hanaoka J. A case report of lung cancer with pulmonary cryptococcosis in contralateral lung (Eng abstr). Jpn J Lung Cancer 2001; 41: 69–72.
Levine MS, Weiss JM, Harrell JH, Cameron TJ, Moser KM. Transthoracic needle aspiration biopsy following negative fiberoptic bronchoscopy in solitary pulmonary nodules. Chest 1988; 93: 1152–5.
Bernard A. Resection of pulmonary nodules using video-assisted thoracic surgery. The Thorax Group. Ann Thorac Surg 1996; 61: 202–5.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kawasaki, H., Ishikawa, K., Kuniyoshi, M. et al. Lung adenocarcinoma with coexisting pulmonary cryptococcoma. Jpn J Thorac Caridovasc Surg 52, 21–25 (2004). https://doi.org/10.1007/s11748-004-0056-5
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s11748-004-0056-5