Skip to main content
Log in

A clinical conundrum: to measure or not measure direct oral anticoagulants before a surgery or procedure?

  • IM - COMMENTARY
  • Published:
Internal and Emergency Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Spyropoulos AC et al (2016) Periprocedural management of patients receiving a vitamin K antagonist or a direct oral anticoagulant requiring an elective procedure or surgery. J Thromb Haemost 14(5):875–885

    Article  CAS  PubMed  Google Scholar 

  2. Liew A, Douketis J (2013) Perioperative management of patients who are receiving a novel oral anticoagulant. Intern Emerg Med 8(6):477–484

    Article  PubMed  Google Scholar 

  3. Barnes GD et al (2015) National trends in ambulatory oral anticoagulant use. Am J Med 128(12):1300-5.e2

    Article  PubMed  Google Scholar 

  4. Douketis JD et al (2015) Perioperative bridging anticoagulation in patients with atrial fibrillation. N Engl J Med 373(9):823–833

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Tripodi A et al (2018) The vexed question of whether or not to measure levels of direct oral anticoagulants before surgery or invasive procedures. Intern Emerg Med. https://doi.org/10.1007/s11739-018-1854-6

    Article  PubMed  Google Scholar 

  6. Tripodi A (2016) To measure or not to measure direct oral anticoagulants before surgery or invasive procedures. J Thromb Haemost 14(7):1325–1327

    Article  CAS  PubMed  Google Scholar 

  7. Spyropoulos AC et al (2016) To measure or not to measure direct oral anticoagulants before surgery or invasive procedures: comment. J Thromb Haemost 14(12):2556–2559

    Article  CAS  PubMed  Google Scholar 

  8. Tripodi A (2016) To measure or not to measure direct oral anticoagulants before surgery or invasive procedures: reply. J Thromb Haemost 14(12):2559–2561

    Article  CAS  PubMed  Google Scholar 

  9. Douketis JD et al (2012) Perioperative management of antithrombotic therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 141(2 Suppl):e326S–e350S

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Douketis JD, Johnson JA, Turpie AG (2004) Low-molecular-weight heparin as bridging anticoagulation during interruption of warfarin: assessment of a standardized periprocedural anticoagulation regimen. Arch Intern Med 164(12):1319–1326

    Article  CAS  PubMed  Google Scholar 

  11. Kovacs MJ et al (2004) Single-arm study of bridging therapy with low-molecular-weight heparin for patients at risk of arterial embolism who require temporary interruption of warfarin. Circulation 110(12):1658–1663

    Article  CAS  PubMed  Google Scholar 

  12. Schulman S, Crowther MA (2012) How I treat with anticoagulants in 2012: new and old anticoagulants, and when and how to switch. Blood 119(13):3016–3023

    Article  CAS  PubMed  Google Scholar 

  13. Prisco D et al (2017) Italian intersociety consensus on DOAC use in internal medicine. Intern Emerg Med 12(3):387–406

    Article  PubMed  Google Scholar 

  14. Tripodi A et al (2017) Position Paper on laboratory testing for patients on direct oral anticoagulants. A Consensus Document from the SISET, FCSA, SIBioC and SIPMeL. Blood Transfus 13:1–9

    Google Scholar 

  15. Levy JH et al (2013) Managing new oral anticoagulants in the perioperative and intensive care unit setting. Anesthesiology 118(6):1466–1474

    Article  CAS  PubMed  Google Scholar 

  16. Cuker A et al (2014) Laboratory measurement of the anticoagulant activity of the non-vitamin K oral anticoagulants. J Am Coll Cardiol 64(11):1128–1139

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Douketis JD et al (2017) The Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE) Study for patients on a direct oral anticoagulant who need an elective surgery or procedure: design and rationale. Thromb Haemost 117(12):2415–2424

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to James D. Douketis.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Statement of human and animal rights

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

None.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Douketis, J.D., Radwi, M. A clinical conundrum: to measure or not measure direct oral anticoagulants before a surgery or procedure?. Intern Emerg Med 13, 997–999 (2018). https://doi.org/10.1007/s11739-018-1930-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11739-018-1930-y

Keywords

Navigation