Quantification of acupuncture effects on peripheral neuropathy of unknown and diabetic cause by nerve conduction studies

摘要

目的

通过神经传导改变的测量评估针灸对于周围神经病变的疗效。

方法

评估192 例周围神经病变患者一年以上。 17 例为糖尿病神经病变, 其中3 例根据海德堡中医规范定义接受传统中医的针灸治疗, 所有神经传导检测均得到改善。 14 例非特异性治疗的患者, 3 例 (21.4%) 患者神经传导检测显示改善, 其余11 例 (78.6%) 患者神经传导检测显示恶化。 全部47 例患者符合周围神经病变不明确病因学的标准, 21 例患者接受针灸治疗, 26 例患者接受非特异性治疗。 所有组别均在治疗前和4 月后进行神经传导检测。

结果

1)糖尿病神经病变, 对照组中3 例患者得到改善, 11 例显示恶化, 组间比较有显著差异。 2)周围神经病变, 针灸组中16 例患者 (76.2%) 得到改善, 而在对照组 中只有4 例 (15.4%) 得到改善。 针灸组中3 例患者 (14.3%) 显示无变化, 2 例 (9.5%) 显示恶化。 但是对照组中7 例 (26.9%) 无变化, 并有15 例 (57.7%) 显示恶化。 具有显著差异。

结论

根据神经传导检测, 针灸治疗周围神经病变具有积极的疗效。

Abstract

Objective

To evaluate the effect of acupuncture on peripheral neuropathy (PN) as measured by changes in nerve conduction studies (NCS).

Methods

192 patients with PN were evaluated over a period of 1 year. In 17 patients diabetic neuropathy was found. 3 of these patients received acupuncture therapy according to classical Chinese medicine as defined by the Heidelberg model of TCM and all improved in NCS. Of the 14 non-specifically treated patients, 3 (21.4%) presented with improved NCS and 11 (78.6%) aggravated in NCS (P≪0.03). An overall of 47 patients met the criteria for PN of undefined aetiology, 21 patients received acupuncture therapy, while 26 patients received no specific treatment. All groups were examined by NCS before treatment and 4 months later.

Results

1) Diabetic neuropathy, in the control-group 3 patients improved and 11 showed an aggravation. Comparison of groups was significantly different. 2) PN, 16 patients (76.2%) in the acupuncture group improved, while only 4 patients in the control group (15.4%) did so. 3 patients in the acupuncture group (14.3%) showed no change and 2 patients an aggravation (9.5%), whereas in the control group 7 patients showed no change (26.9%) and 15 an aggravation (57.7%).Comparison of the groups was significantly different.

Conclusion

There is a positive effect of acupuncture on PN, as measured by objective parameters (NCS).