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The influence of HF treatment on corrosion resistance and in vitro biocompatibility of Mg-Zn-Zr alloy

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Abstract

The samples made of a Mg-2.5wt.%Zn-0.5wt.%Zr alloy were immersed in the 20% hydrofluoric acid (HF) solution at room temperature for different time, with the aim of improving the properties of magnesium (Mg) alloy in applications as biomaterials. The corrosion resistance and in vitro biocompatibility of untreated and fluoride-coated samples were investigated. The results show that the optimum process is to immerse Mg alloys in the 20% HF solution for 6 h. After the immersion, a dense magnesium fluoride (MgF2) coating of 0.5 μm was synthesized on the surface of Mg-Zn-Zr alloy. Polarization tests recorded a reduction in the corrosion current density from 2.10 to 0.05 μA/cm2 due to the MgF2 protective coating. Immersion tests in the simulated body fluid (SBF) also reveal a much milder corrosion on the fluoride-coated samples, and its corrosion rate was calculated to be 0.05 mm/yr. Hemolysis test suggests that the conversion coated Mg alloy has no obvious hemolysis reaction. The hemolysis ratio (HR) of the samples decreases from 11.34% to 1.86% with the HF treatment, which meets the requirements of biomaterials (HR < 5%). The coculture of 3T3 fibroblasts with Mg alloy results in the adhesion and proliferation of cells on the surface of fluoride-coated samples. All the results show that the MgF2 conversion coating would markedly improve the corrosion resistance and in vitro biocompatibility of Mg-Zn-Zr alloy.

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Authors and Affiliations

  1. School of Materials Science and Engineering, Tianjin University of Technology, Tianjin, 300384, China

    Xin-Yu Ye, Min-Fang Chen, Chen You & De-Bao Liu

  2. Tianjin Key Laboratory of Photoelectric Materials and Devices, Tianjin University of Technology, Tianjin, 300384, China

    Chen You

  3. Key Laboratory of Display Materials and Photoelectric Device (Ministry of Education), Tianjin University of Technology, Tianjin, 300384, China

    De-Bao Liu

Authors
  1. Xin-Yu Ye
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  2. Min-Fang Chen
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  3. Chen You
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  4. De-Bao Liu
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Correspondence to Min-Fang Chen.

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Ye, XY., Chen, MF., You, C. et al. The influence of HF treatment on corrosion resistance and in vitro biocompatibility of Mg-Zn-Zr alloy. Front. Mater. Sci. China 4, 132–138 (2010). https://doi.org/10.1007/s11706-010-0025-0

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  • DOI: https://doi.org/10.1007/s11706-010-0025-0

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