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Fabrication and biocompatibility in vitro of potassium titanate biological thin film/titanium alloy biological composite

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Abstract

A potassium titanate biological thin film/titanium alloy biological composite was fabricated by way of bionic chemistry. The biocompatibility in vitro of Ti-15Mo-3Nb and the potassium titanate biological thin film/titanium alloy was studied using simulated body fluid cultivation, kinetic clotting of blood and osteoblast cell cultivation experiments in vitro. By comparing the biological properties of both materials, the following conclusions can be obtained: (1) The deposition of a calcium phosphate layer was not found on the surface of Ti-15Mo-3Nb, so it was bioinert. Because the network of potassium titanate biological thin film could induce the deposition of a calcium phosphate layer, this showed that it had excellent bioactivity. (2) According to the values of kinetic clotting, the blood coagulation time of the potassium titanate biological thin film was more than that of Ti-15Mo-3Nb. It was obvious that the potassium titanate biological thin film possessed good hemocompatibility. (3) The cell compatibility of both materials was very good. However, the growth trend and multiplication of osteoblast cells on the surface of potassium titanate biological thin film was better, which made for the concrescence of wounds during the earlier period. As a result, the potassium titanate biological thin film/titanium alloy showed better biocompatibility and bioactivity.

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References

  1. Li Q. Metal materials for organism. Metallic Functional Materials, 2000, 7(4): 8–14 (in Chinese)

    Google Scholar 

  2. Long M, Rack H J. Titanium alloys in total joint replacement—a materials science perspective. Biomaterials, 1998, 19(18): 1,621–1,639

    Article  CAS  Google Scholar 

  3. Ren Y B, Yang K, Liang Y. Research and development of new biomedical metal material. Materials Review, 2002, 16(2): 12–15 (in Chinese)

    Google Scholar 

  4. Ning C Q, Zhou Y, Jia G C. Mechanical properties and biological behavior of titanium/hydroxyapatite biocomposite. Journal of the Chinese Ceramic Society, 2000, 28(5): 483–486 (in Chinese)

    CAS  Google Scholar 

  5. Yan W-Q, Nakamura T, Kawanabe K, et al. Apatite layer-coated titanium for use as bone bonding implants. Biomaterials, 1997, 18(17): 1,185–1,190

    Article  CAS  Google Scholar 

  6. Hayashi K, Mashima T, Uenoyama K. The effect of hydroxyapatite coating on bony ingrowth into grooved titanium implants. Biomaterials, 1999, 20(2): 111–119

    Article  CAS  Google Scholar 

  7. Hayashi K, Matsuguchi N, Uenoyama K, et al. Evaluation of metal implants coated with several types of ceramics as biomaterials. Journal Biomedical Materials Research, 1989, 23(11): 1,247–1,259

    CAS  Google Scholar 

  8. Xi Y X, Wang Y J. Research progress on preparation of HA bioactive ceramic coating. Ceramics Engineering, 1999, 33(4): 14–17 (in Chinese)

    CAS  Google Scholar 

  9. Reis R L, Monteiro F J, Hastings G W. Stability of hydroxyapatite plasma-sprayed coated Ti-6Al-4V under cylic bending in simulated physiological solutions. Journal of Materials Science: Materials in Medicine, 1994, 5(6–7): 457–462

    Article  Google Scholar 

  10. Yang C Y, Wang B C, Chang E, et al. Bond degradation at the plasma-sprayed HA coating/Ti-6Al-4V alloy interface: An in vitro study. Journal of Materials Science: Materials in Medicine, 1995, 6(5): 258–265

    Article  CAS  Google Scholar 

  11. Kokubo T, Kushitani H, Sakka S, et al. Solution able to reproduce in vivo surface-structure changes in bioactive glass-ceramics A-W. Journal of Biomedical Materials Research, 1990, 24(6): 721–734

    Article  CAS  Google Scholar 

  12. The document promulgated by Ministry of Health of the People’s Republic of China. (89) Health & Medicine file No. 44, 1987 (in Chinese)

  13. Yu T Y, Zhang X D. Biomedical Materials. Tianjin: Tianjin University Press, 2000 (in Chinese)

    Google Scholar 

  14. Qian Y T. Crystallochemical Introduction. 2nd ed. Hefei: University of Science and Technology of China Press, 1999 (in Chinese)

    Google Scholar 

  15. Huang J F. Inorganic reinforced whisker I: Potassium titanate whiskers. Journal of Salt Lake Research, 1994, 2(3): 69–75 (in Chinese)

    Google Scholar 

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Authors and Affiliations

  1. School of Materials Science & Engineering, Hebei University of Technology, Tianjin, 300130, China

    Qi Yumin, Cui Chunxiang, Liu Shuangjin & Wang Huifen

  2. Hospital of Hebei University of Technology, Tianjin, 300130, China

    He Yun

Authors
  1. Qi Yumin
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  2. He Yun
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  3. Cui Chunxiang
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  4. Liu Shuangjin
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  5. Wang Huifen
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Corresponding author

Correspondence to Cui Chunxiang.

Additional information

Translated from Journal of Functional Materials, 2006, 37(10): 1,638–1,642 (in Chinese)

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Qi, Y., He, Y., Cui, C. et al. Fabrication and biocompatibility in vitro of potassium titanate biological thin film/titanium alloy biological composite. Front. Mater. Sci. China 1, 252–257 (2007). https://doi.org/10.1007/s11706-007-0045-6

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  • DOI: https://doi.org/10.1007/s11706-007-0045-6

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