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Surgical outcomes of robot-assisted laparoscopic partial nephrectomy for cystic renal cell carcinoma

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Abstract

To compare the surgical outcomes of robot-assisted partial nephrectomy (RAPN) between patients with cystic renal cell carcinoma (cRCC) and those with solid RCC (sRCC). We retrospectively analyzed 1065 patients who underwent RAPN between 2013 and 2020 for a pathological diagnosis of RCC. Patients were divided into two groups: cRCC and sRCC. cRCC was diagnosed according to the Bosniak classification system. To minimize selection bias between the two groups, patient variables (patient characteristics) and tumor factors (such as size and complexity) were adjusted using 1:1 propensity score matching. Of the 1065 patients, 94 (9%) were diagnosed with cRCC. Bosniak categories of IIF, III, and IV were noted in 4 (4.2%), 31 (33%), and 59 (63%) patients, respectively. After matching, 83 patients each were assigned to the cRCC and sRCC groups. The operation time in cRCC tended to be longer than in sRCC but not significantly different (164 vs. 150 min, P = 0.0767). Other surgical outcomes, such as change in estimated glomerular filtration rate ( – 5.2 vs.  – 7.2%, P = 0.1577), perioperative complications (14.5 vs. 15.7%, P = 0.9225), estimated blood loss (62 vs. 58 mL, P = 0.5613), or negative surgical margin status (100 vs 99%, P = 0.236), were not significantly different between the two groups. During the follow-up period of about 2 years, one and two patients showed recurrence in the cRCC and sRCC groups, respectively. The surgical outcomes of RAPN were similar between cRCC and sRCC, demonstrating the feasibility of RAPN for cRCC.

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Acknowledgements

The authors thank Noriko Hata for their secretarial work.

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Authors and Affiliations

  1. Department of Urology, Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan

    Takafumi Yagisawa, Toshio Takagi, Kazuhiko Yoshida, Keisuke Hata, Junpei Iizuka, Yasuto Muromiya & Kazunari Tanabe

  2. Department of Urology, Tokyo Women’s Medical University Medical Center East, Tokyo, Japan

    Tsunenori Kondo

Authors
  1. Takafumi Yagisawa
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  2. Toshio Takagi
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  3. Kazuhiko Yoshida
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  4. Keisuke Hata
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  5. Junpei Iizuka
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  6. Yasuto Muromiya
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  7. Tsunenori Kondo
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  8. Kazunari Tanabe
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Correspondence to Toshio Takagi.

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Ethical approval

This retrospective study was approved by the Institutional Ethics Committee of Tokyo Women’s Medical University (ID: 2020–0062). The present study was conducted in accordance with the tenets of the Declaration of Helsinki of 1964 and its later amendments. Owing to the retrospective nature of this study, the need for informed consent was waived.

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Yagisawa, T., Takagi, T., Yoshida, K. et al. Surgical outcomes of robot-assisted laparoscopic partial nephrectomy for cystic renal cell carcinoma. J Robotic Surg 16, 649–654 (2022). https://doi.org/10.1007/s11701-021-01292-7

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  • DOI: https://doi.org/10.1007/s11701-021-01292-7

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