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Evaluation of Myocardial Function Following SADI-S

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Abstract

Purpose

The aim of this study was to compare myocardial mechanics using global longitudinal strain (GLS) before and after single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S).

Materials and Methods

A total of 21 obese patients undergoing SADI-S were prospectively included. Transthoracic echocardiography was performed before and after the procedure, and left ventricle (LV) and right ventricle (RV) strain was assessed by two-dimensional speckle-tracking imaging (2DST).

Results

Mean time between pre-procedural and post-procedural echocardiograms was 9.2 ± 3.3 months. Postoperatively, %total weight loss (%TWL) was 33.0 ± 1.7 and % excess weight loss (%EWL) was 75.5 ± 3.6. Body mass index (BMI) significantly decreased after surgery (45.6 ± 1.2 vs 29.6 ± 1.0; p < 0.001). Postoperatively, LV GLS experienced a significant improvement (−19.8% ± 0.5 vs −22.2% ± 0.4; p < 0.001). Regarding other relevant functional parameters, RV free-wall strain was equally recovered (−19.1% ± 0.7 vs −21.0% ± 0.8; p 0.047).

Conclusions

This study demonstrates important and favourable changes in cardiac deformation parameters after performing SADI-S. Malabsorptive bariatric techniques such as SADI-S induce significant weight loss, leading to an improvement in subclinical myocardial function in patients with obesity.

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Acknowledgements

Alejandro Cruz-Utrilla holds a research-training contract ¨Rio Hortega¨ (CM20/00164) from the Spanish Ministry of Science and Innovation (Instituto de Salud Carlos III).

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Author notes

  1. Adriana Ruano-Campos and Alejandro Cruz-Utrilla contributed equally to this work.

Authors and Affiliations

  1. Surgery Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Complutense University of Madrid, Hospital Clínico San Carlos, C/ Prof. Martin Lagos s/n, 28040, Madrid, Spain

    Adriana Ruano-Campos, Leyre López-Antoñanzas, Antonio Torres García & Andrés Sánchez-Pernaute

  2. Cardiology Department, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria del Hospital 12 de Octubre (i+12), Biomedical Research Network Centre for Cardiovascular Disease (CIBERCV), Madrid, Spain

    Alejandro Cruz-Utrilla

  3. Cardiology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Complutense University of Madrid, Madrid, Spain

    Maria Luaces & Leopoldo Pérez de Isla

  4. Endocrinology and Nutrition Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Complutense University of Madrid, Madrid, Spain

    Miguel Ángel Rubio Herrera

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  1. Adriana Ruano-Campos
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Corresponding author

Correspondence to Adriana Ruano-Campos.

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Ethics Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Conflict of Interest

Adriana Ruano-Campos has no conflict of interest to declare. Alejandro Cruz-Utrilla has no conflict of interest to declare. Leyre López-Antoñanzas has no conflict of interest to declare. Maria Luaces has no conflict of interest to declare. Leopoldo Pérez de Isla has no conflict of interest to declare. Miguel Angel Rubio Herrera has no conflict of interest to declare. Antonio Torres García has no conflict of interest to declare. Andres Sanchez-Pernaute has no conflict of interest to declare.

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Ruano-Campos, A., Cruz-Utrilla, A., López-Antoñanzas, L. et al. Evaluation of Myocardial Function Following SADI-S. OBES SURG 31, 3109–3115 (2021). https://doi.org/10.1007/s11695-021-05349-2

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  • DOI: https://doi.org/10.1007/s11695-021-05349-2

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