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Orthostatic Intolerance after Bariatric Surgery: a Systematic Review

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Abstract

Predisposing factors of new-onset orthostatic intolerance (OI) after bariatric surgery (BS) are unknown. The purpose of this study is to summarize current existing data on new-onset OI after BS. Materials and methods were considered for a search of articles that were published by the 30th of July 2020. A systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and in line with the protocol agreed by all authors was conducted. Of the 604 initially identified articles, four studies were found to match the established criteria and were extracted for eligibility. 83.3% were female. Hypertension, type 2 diabetes mellitus, and obstructive sleep apnea syndrome were the most frequently reported comorbidities. Surgical intervention such as revision, conversion, or reversal was not documented in these studies. Awareness of this issue must be raised due to the possibility of reduced quality of life and the risk of syncope.

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References

  1. Adams TD, Gress RE, Smith SC, et al. Long-term mortality after gastric bypass surgery. N Engl J Med. 2007;357(8):753–61.

    Article  CAS  PubMed  Google Scholar 

  2. Schauer PR, Bhatt DL, Kirwan JP, et al. Bariatric surgery versus intensive medical therapy for diabetes - 5-year outcomes. N Engl J Med. 2017;376(7):641–51.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Gagner M, Deitel M, Erickson AL, et al. Survey on laparoscopic sleeve gastrectomy (LSG) at the Fourth International Consensus Summit on Sleeve Gastrectomy. Obes Surg. 2013;23(12):2013–7.

    Article  PubMed  Google Scholar 

  4. Kumar N. Obesity surgery: a word of neurologic caution. Neurology. 2007;68:36–8.

    Article  Google Scholar 

  5. Berger JR. The neurological complications of bariatric surgery. Arch Neurol. 2004;61:1185–9.

    Article  PubMed  Google Scholar 

  6. Juhasz-Pocsine K, Rudnicki SA, Archer RL, et al. Neurologic complications of gastric bypass surgery for morbid obesity. Neurology. 2007;68:1843–50.

    Article  PubMed  Google Scholar 

  7. Freeman R, Wieling W, Axelrod FB, et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Auton Neurisci. 2011;161:46–8.

    Article  Google Scholar 

  8. Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ. 2009;339:b2700. https://doi.org/10.1136/bmj.b2700.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Zhang JB, Tamboli RA, Albaugh VL, et al. The incidence of orthostatic intolerance after bariatric surgery. Obes Sci Pract. 2019;6(1):76–83.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Rubinshtein R, Ciubotaru M, Elad H, et al. Severe orthostatic hypotension following weight reduction surgery. Arch Intern Med. 2001;161(17):2145–7.

    Article  CAS  PubMed  Google Scholar 

  11. Billakanty SR, Kligman MD, Kanjwal YM, et al. New-onset orthostatic intolerance following bariatric surgery. Pacing Clin Electrophysiol. 2008;31(7):884–8.

    Article  PubMed  Google Scholar 

  12. Lascano CA, Szomstein S, Zundel N, et al. Diabetes mellitus-associated diffuse autonomic dysfunction causing debilitating hypotension manifested after rapid weight loss in a morbidly obese patient: case report and review of the literature. Surg Obes Relat Dis. 2005;1(4):443–6.

    Article  PubMed  Google Scholar 

  13. Welbourn R, Hollyman M, Kinsman R, et al. Bariatric surgery worldwide: baseline demographic description and one-year outcomes from the Fourth IFSO Global Registry Report 2018. Obes Surg. 2019;29(3):782–95.

    Article  PubMed  Google Scholar 

  14. Lambert E, Sari CI, Dawood T, et al. Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults. Hypertension. 2010;56(3):351–8.

    Article  CAS  PubMed  Google Scholar 

  15. Scarpellini E, Arts J, Karamanolis G, et al. International consensus on the diagnosis and management of dumping syndrome. Nat Rev Endocrinol. 2020;16(8):448–66.

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Radwan Kassir.

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Appendix. Search Strategy

Appendix. Search Strategy

Our search strategy was performed by utilizing the below words:

Summation of #1-8: #1 ((bariatric [MeSH Terms]) OR (bariatric [Title/Abstract])) AND (((((orthostatic[MeSH Terms]) OR (orthostatic [Title/Abstract])) OR (syncope [MeSH Terms])) OR (syncope [Title/Abstract])) OR (tilt test [Title/Abstract])), #2 ((Neurologic complication [Title/Abstract])) AND ((((((bariatric [MeSH Terms]) OR (bariatric [Title/Abstract])) OR (weight loss [MeSH Terms])) OR (weight loss [Title/Abstract])) OR (gastric bypass [Title/Abstract])) OR (sleeve gastrectomy [Title/Abstract])), #3 ((weight loss [MeSH Terms]) OR (weight loss [Title/Abstract])) AND (((((orthostatic [MeSH Terms]) OR (orthostatic [Title/Abstract])) OR (syncope [MeSH Terms])) OR (syncope [Title/Abstract])) OR (tilt test [Title/Abstract])), #4 ((Sleeve gastrectomy [Title/Abstract])) AND (((((orthostatic [MeSH Terms]) OR (orthostatic [Title/Abstract])) OR (syncope [MeSH Terms])) OR (syncope [Title/Abstract])) OR (tilt test [Title/Abstract])), #5 ((Metabolic surgery [Title/Abstract])) AND (((((orthostatic [MeSH Terms]) OR (orthostatic [Title/Abstract])) OR (syncope [MeSH Terms])) OR (syncope [Title/Abstract])) OR (tilt test [Title/Abstract])), #6 ((gastric bypass [MeSH Terms]) OR (gastric bypass [Title/Abstract])) AND (((((orthostatic [MeSH Terms]) OR (orthostatic [Title/Abstract])) OR (syncope [MeSH Terms])) OR (syncope [Title/Abstract])) OR (tilt test [Title/Abstract])), #7 ((body mass index [MeSH Terms]) OR (body mass index [Title/Abstract])) AND (((((orthostatic [MeSH Terms]) OR (orthostatic [Title/Abstract])) OR (syncope [MeSH Terms])) OR (syncope [Title/Abstract])) OR (tilt test [Title/Abstract])), #8 ((obesity [MeSH Terms]) OR (obesity [Title/Abstract])) AND (((((orthostatic [MeSH Terms]) OR (orthostatic [Title/Abstract])) OR (syncope [MeSH Terms])) OR (syncope [Title/Abstract])) OR (tilt test [Title/Abstract]))

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Kermansaravi, M., Chiappetta, S., Lainas, P. et al. Orthostatic Intolerance after Bariatric Surgery: a Systematic Review. OBES SURG 31, 2250–2254 (2021). https://doi.org/10.1007/s11695-021-05266-4

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