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Effect of Sleeve Gastrectomy on Platelet Counts and Mean Platelet Volumes

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A Correction to this article was published on 21 May 2018

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Abstract

Background

Obesity is a chronic metabolic disorder associated with cardiovascular disease, characterized by a chronic proinflammatory and prothrombotic state. The size and hemostatic potential of circulating platelets (PLTs) differ, with larger PLTs containing more granules and producing greater amounts of vasoactive and prothrombotic factors. This study aimed to investigate the effect of laparoscopic sleeve gastrectomy (LSG) on PLT count and mean platelet volume (MPV) in morbidly obese patients.

Methods

Two hundred five patients (females, n = 143; males, n = 62) who attended monitoring visits in the period prior to LSG and for 6 months after surgery were included in this study. Routine physical examination findings and laboratory parameters recorded preoperatively were compared with the same parameters in the postoperative 6th month.

Results

The mean age of the patients was 37.36 ± 10.93 years. The mean preoperative body mass index (BMI) of the patients was 47.65 kg/m2, whereas the mean postoperative BMI at 6 months was 31.49 kg/m2. Prior to LSG, the mean PLT count was 314.16 ± 76.40 × 109/L. At the postoperative 6th month, the mean PLT count was significantly reduced (263.17 ± 65.67 × 109/L, p < 0.001). In the preoperative period, the MPV was 10.12 ± 0.88 fL. In the postoperative period, it was significantly increased (10.41 ± 1.23 fL, p > 0.001). Both preoperatively and postoperatively, PLT counts were significantly higher in females than in males. After LSG, the MPV increased in both females and males.

Conclusions

The results demonstrated that PLT counts decreased and MPV levels increased significantly after LSG and that the decrease in PLT counts was independent of changes in BMI.

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Change history

  • 21 May 2018

    In the original article, in the Results section of the Abstract the text “…(10.41 ± 1.23 fL, p > 0.001)” should be changed to “…(10.41 ± 1.23 fL, p < 0.001)”. The same error occurs on the next page of the article in the second paragraph of the Results section of the main text.

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Authors and Affiliations

  1. Department of Endocrinology and Metabolism, Faculty of Medicine, Gaziosmanpasa University, School of Medicine, 60100, Tokat, Turkey

    Faruk Kutluturk

  2. Department of General Surgery, Gaziosmanpasa University, School of Medicine, Tokat, Turkey

    Zeki Ozsoy

Authors
  1. Faruk Kutluturk
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  2. Zeki Ozsoy
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Corresponding author

Correspondence to Faruk Kutluturk.

Ethics declarations

To conduct the study, approval of the Clinical Research Ethics Committee of the Faculty of Medicine, University of Gaziosmanpasa University was obtained (17-KAEK-167). The study was carried out in accordance with the Declaration of Helsinki (2013) of the World Medical Association.

Conflict of Interest

The authors declare that they have no conflicts of interest.

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Kutluturk, F., Ozsoy, Z. Effect of Sleeve Gastrectomy on Platelet Counts and Mean Platelet Volumes. OBES SURG 28, 3159–3164 (2018). https://doi.org/10.1007/s11695-018-3287-8

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  • DOI: https://doi.org/10.1007/s11695-018-3287-8

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