Skip to main content

Advertisement

Log in

A New Algorithm to Reduce the Incidence of Gastroesophageal Reflux Symptoms after Laparoscopic Sleeve Gastrectomy.

  • Original Contributions
  • Published:
Obesity Surgery Aims and scope Submit manuscript

Abstract

Background

Laparoscopic sleeve gastrectomy (LSG) is one of the most prefered treatment option for morbid obesity. However, the effects of LSG on gastroesophageal reflux disease (GERD) are controversial. Asymptomatic GERD and hiatal hernia (HH) is common in obese patients. Therefore, it is important to identify the high risk patients prior to surgery. This study aims to evaluate efficacy of cruroplasty for HH during LSG in morbidly obese patients using ambulatory pH monitoring (APM) results, and to investigate the patients’ selection criteria for this procedure.

Methods

This retrospective study includes outcomes of 59 patients who underwent LSG and HH repair according to our patient selection algorithm. Outcomes included preoperative GERD Health-Related Quality of Life (GERD-HRQL) questionnaire, APM results, percentage of postoperative excess weight loss, and total weight loss.

Results

For a total of 402 patients, APM was applied in 70 patients who had a positive score of GERD-HRQL, and 59 patients underwent LSG and concomitant HH repair who had a DeMeester score of 14.7% or above. There was no statistically significant difference in weight loss at 6 and 12-month follow-up. Two patients (3.3%) had symptoms of GERD at 12 months postoperatively, and only one (1.6%) patient required treatment of proton pump inhibitor for reflux. In the total cohort, 11 (2.7%) patients also evolved de novo GERD symptoms.

Conclusions

This study confirm that careful attention to patient selection and surgical technique can reduce the symptoms of GERD at short-term. Routine bilateral crus exploration could be a major risk factor of postoperative GERD.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Dent J, El-Serag HB, Wallander MA, et al. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2005;54:710–7.

  2. El-Serag H. Role of obesity in GORD-related disorders. Gut. 2008;57:281–4.

    Article  PubMed  Google Scholar 

  3. De Groot NL, Burgerhart JS, Van De Meeberg PC, et al. Systematic review: the effects of conservative and surgical treatment for obesity on gastrooesophageal reflux disease. Aliment Pharmacol Ther. 2009;30:1091–02.

  4. Prachand VN, Alverdy JC. Gastroesophageal reflux disease and severe obesity: fundoplication or bariatric surgery? World J Gastroenterol. 2010;16(30):3757–61.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Varela JE, Hinojosa MW, Nguyen NT. Laparoscopic fundoplication compared with laparoscopic gastric bypass in morbidly obese patients with gastroesophageal reflux disease. Surg Obes Relat Dis. 2009;5(2):139–43.

    Article  PubMed  Google Scholar 

  6. Chiu S, Birch DW, Shi X, et al. Effect of sleeve gastrectomy on gastroesophageal reflux disease: a systematic review. Surg Obes Relat Dis. 2011;7:51015.

  7. Daes J, Jimenez ME, Said N, et al. Laparoscopic sleeve gastrectomy: symptoms of gastroesophageal reflux can be reduced by changes in surgical technique. Obes Surg. 2012;22(12):1874–9.

  8. Lazoura O, Zacharoulis D, Triantafyllidis G, et al. Symptoms of gastroesophageal reflux following laparoscopic sleeve gastrectomy are related to the final shape of the sleeve as depicted by radiology. Obes Surg. 2011;21(3):295–9.

  9. Soricelli E, Casella G, Rizzello M, et al. Initial experience with laparoscopic crural closure in the management of hiatal hernia in obese patients undergoing sleeve gastrectomy. Obes Surg. 2010;20(8):1149–53.

  10. Braghetto I, Lanzarini E, Korn O, et al. Manometric changes of the lower esophageal sphincter after sleeve gastrectomy in obese patients. Obes Surg. 2010;20(3):357–62.

  11. Carter PR, LeBlanc KA, Hausmann MG, et al. Association between gastroesophageal reflux disease and laparoscopic sleeve gastrectomy. Surg Obes Relat Dis. 2011;7:569–74.

  12. Burgerhart JS, Charlotte AI, Schotborgh, et al. Effect of sleeve gastrectomy on gastroesophageal reflux. Obes Surg. 2014;24:1436.

  13. Melissas J, Koukouraki S, Askoxylakis J, et al. Sleeve gastrectomy—a restrictive procedure? Obes Surg. 2007;17:57–62.

  14. Petersen W, Meile T, Küper MA, et al. Functional importance of laparoscopic sleeve gastrectomy for the lower esophageal sphincter in patients with morbid obesity. Obes Surg. 2012;22:360–6.

  15. Cottam D, Qureshi FG, Mattar SG, et al. Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesity. Surg Endosc. 2006;20(6):859–63.

  16. Fass R. The pathophysiological mechanisms of GERD in the obese patient. Dig Dis Sci. 2008;53(9):2300–6.

    Article  CAS  PubMed  Google Scholar 

  17. Kahrilas PJ, Quigley EM. Clinical esophageal pH recording: a technical review for practice guideline development. Gastroenterology. 1996;110:1982–96.

  18. Johnson LF, De Meester TR. Development of the 24-h intraesophageal pH monitoring composite scoring system. J Clin Gastroenterol. 1986;1:747–67.

    Google Scholar 

  19. Fuchs KH, DeMeester TR, Albertucci M. Specificity and sensitivity of objective diagnosis of gastroesophageal reflux disease. Surgery. 1987;102(4):575–80.

    CAS  PubMed  Google Scholar 

  20. Gorodner V, Buxhoeveden R, Clemente G, et al. Does laparoscopic sleeve gastrectomy have any influence on gastroesophageal reflux disease? Preliminary results. Surg Endosc. 2015;29(7):1760–8.

  21. Velanovich V. The development of the GERD-HRQL symptom severity instrument. Dis Esophagus. 2007;20(2):130–4.

    Article  CAS  PubMed  Google Scholar 

  22. Del Genio G, Tolone S, Limongelli P, et al. Sleeve gastrectomy and development of "de novo" gastroesophageal reflux. Obes Surg. 2014;24(1):71–7.

  23. Rebecchi F, Allaix ME, Giaccone C, et al. Gastroesophageal reflux disease and laparoscopic sleeve gastrectomy: a physiopathologic evaluation. Ann Surg. 2014;260(5):909–14.

  24. Melissas J, Daskalakis M, Koukouraki S, et al. Sleeve gastrectomy—a "food limiting" operation. Obes Surg. 2008;18(10):1251–6.

  25. El Chaar M, Ezeji G, Claros L, et al. Short-term results of laparoscopic sleeve gastrectomy in combination with hiatal hernia repair: experience in a single accredited center. Obes Surg. 2016;26(1):68–76.

    Article  PubMed  Google Scholar 

  26. Wölnerhanssen B, Peterli R. State of the art: sleeve gastrectomy. Dig Surg. 2014;31(1):40–7.

    Article  PubMed  Google Scholar 

  27. Wang Z, Dai X, Xie H, et al. The efficacy of staple line reinforcement during laparoscopic sleeve gastrectomy: a meta-analysis of randomized controlled trials. Int J Surg. 2016;25:145–52.

    Article  PubMed  Google Scholar 

  28. Himpens J, Dobbeleir J, Peeters G. Long term results of laparoscopic sleeve gastrectomy for obesity. Ann Surg. 2010;252(2):319–24.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ilhan Ece.

Ethics declarations

Limitations

The study was a retrospective analysis.

Conflict of Interest

The authors declare that they have no competing interests.

Statement of Informed Consent

The need for patient informed consent for this retrospective study was waived by the institutional review board.

Ethical Approval

This study was approved by the institutional ethics committee and has been performed in accordance with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ece, I., Yilmaz, H., Acar, F. et al. A New Algorithm to Reduce the Incidence of Gastroesophageal Reflux Symptoms after Laparoscopic Sleeve Gastrectomy.. OBES SURG 27, 1460–1465 (2017). https://doi.org/10.1007/s11695-016-2518-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11695-016-2518-0

Keywords

Navigation