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24-h Multichannel Intraluminal Impedance PH-metry 1 Year After Laparocopic Sleeve Gastrectomy: an Objective Assessment of Gastroesophageal Reflux Disease

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Abstract

Introduction

It is not yet clear if laparoscopic sleeve gastrectomy (LSG) causes newly onset gastroesophageal reflux (GERD) or worsens already existing GERD. This is due to the absence of prospective studies using objective assessment measures of GERD such as pH monitoring. Our study aims at assessing GERD 1-year post-LSG procedure for obesity.

Materials and Methods

Twelve asymptomatic obese patients were studied prospectively by using 24-h multichannel intraluminal impedance-pHmetry (MIIpH) pre- and 12 months post-LSG.

Results

Of patients’ 1-year post-LSG, 83.33 % of patients’ suffer from GERD (either newly onset or worsening of already existing) as indicated by abnormal DeMeester score. Mean DeMeester score 1-year post LSG was 47, almost 2.5 times higher than the preoperative score (p = 0.072). The percentage of total time with pH lower than four was statistically significant higher postoperatively (13.27 % vs 3.87 %, p = 0.048).

Conclusion

This study is one of the few assessing GERD post-LSG by using 24-h MIIpH. The majority of patients suffer from GERD 12 months postoperatively, implying that close postoperative monitor for GERD with the use of pH testing and upper gastrointestinal endoscopy in order to early diagnose GERD and identify possible mucosal injury and also a prophylactic proton pump inhibitor use may be of great importance.

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Authors and Affiliations

  1. Foregut Department, 1st Propaedeutic Surgical Department, Hippokration General Hospital of Athens, National and Kapodistrian University of Athens, 114 Vas Sofias Av, 115 27, Athens, Greece

    Doulami Georgia, Triantafyllou Stamatina & Theodorou Dimitrios

  2. Bariatric Surgery Department, 1st Propaedeutic Surgical Department, Hippokration General Hospital of Athens, National and Kapodistrian University of Athens, Athens, Greece

    Natoudi Maria, Albanopoulos Konstantinos & Leandros Emmanouil

  3. 1st Propaedeutic Surgical Department, Hippokration General Hospital of Athens, National and Kapodistrian University of Athens, Athens, Greece

    Filis Konstantinos & Zografos Georgios

Authors
  1. Doulami Georgia
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  2. Triantafyllou Stamatina
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  3. Natoudi Maria
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  4. Albanopoulos Konstantinos
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  5. Filis Konstantinos
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  6. Leandros Emmanouil
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  7. Zografos Georgios
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  8. Theodorou Dimitrios
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Correspondence to Doulami Georgia.

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All authors declare having no conflict of interest.

Statement of Human and Animal Rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of our institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.

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Georgia, D., Stamatina, T., Maria, N. et al. 24-h Multichannel Intraluminal Impedance PH-metry 1 Year After Laparocopic Sleeve Gastrectomy: an Objective Assessment of Gastroesophageal Reflux Disease. OBES SURG 27, 749–753 (2017). https://doi.org/10.1007/s11695-016-2359-x

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  • DOI: https://doi.org/10.1007/s11695-016-2359-x

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