Abstract
Background
The effectiveness of restrictive procedures has been inferior to that of malabsorbitive ones. Recent variants of restrictive procedures, i.e., gastric banding and sleeve gastrectomy, confirm the strive for more efficacious solutions with less complications. We investigated the balance between effectiveness and complications for a new restrictive procedure, a Transoral Endoscopic Vertical Gastroplasty (TOGa®)
Methods
Seventy-nine morbidly obese patients were submitted to one out of three surgical procedures: TOGa® (29 patients), laparoscopic gastric bypass (LRYGBP; 20 patients), and biliopancreatic diversion (BPD; 30 patients). Mean BMI were 41.7 (35.4–46.6), 44.8 (36.4–54), and 47.5 (41–60.3), respectively. All the patients reached a 2-year follow-up.
Results
In TOGa® group BMI, respectively at 12 and 24 months, was 34.5 and 35.5, with 44 and 48.3 % of patients with BMI lower than 35. In LRYGBP group, BMI was 30.7 and 29.2 kg/m2, with 80 and 85 % of patients with BMI < 35. In BPD group, BMI was 30 and 29.6 kg/m2, with 100 and 93.3 % of patients with BMI < 35. In TOGa® group, 59 % of patients with an initial BMI < 45 reached a BMI < 35, in comparison to 48 % recorded in the whole group and to 14.3 % in patients with initial BMI ≥ 45.
Conclusions
In selected patients, TOGa®, was associated with good results after two years in terms of weight loss, even in comparison with LRYGBP and BPD. Minimal trauma, absence of complications, and short hospital stay justify this procedure for patients with low BMI.
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Acknowledgments
The authors are grateful to Mrs. Carolina Gualtieri for her precious cooperation as Clinical Research Coordinator. Special thanks to GianLuigi Conte, M.D. and his psychiatric team, for patient assistance.
Conflict of Interest Statement
Costamagna G. and Perri V have a potential conflict of interest as they were both supported by a grant from Satiety, Inc, U.S.A. All the other authors, (Nanni G., Familiari P, Mor A., Iaconelli A., Rubino F., Boldrini G, Salerno MP, Leccesi L, Iesari S., Sollazzi L, Perilli W, Castagneto M, and Mingrone G) declare no conflict of interest directly or indirectly related to this manuscript.
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Nanni, G., Familiari, P., Mor, A. et al. Effectiveness of the Transoral Endoscopic Vertical Gastroplasty (TOGa®): a Good Balance Between Weight Loss and Complications, if Compared with Gastric Bypass and Biliopancreatic Diversion. OBES SURG 22, 1897–1902 (2012). https://doi.org/10.1007/s11695-012-0770-5
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DOI: https://doi.org/10.1007/s11695-012-0770-5