Abstract
Malabsorptive syndromes and micronutrient deficiencies represent well-known long-term complications of bariatric surgery. Wernicke's encephalopathy (WE), a neurologic manifestation of thiamine deficiency, has been classically associated with alcoholism or severe malnutrition, but rarely reported after bariatric surgery. Herein, we describe the case of a 27-year-old woman that developed WE 10 months after laparoscopic Roux-en-Y gastric bypass for morbid obesity that was initially misdiagnosed with a consequent retard in the appropriate treatment. Although only a few sporadic cases have been reported in the literature, all surgeons and physicians involved in the care of bariatric patients must be aware of this potentially serious complication.
References
Calle EE, Teras LR, Thun MJ. Obesity and mortality. N Engl J Med. 2005;353:2197–9.
Hubbard VS, Hall WH. Gastrointestinal surgery for severe obesity. Obes Surg. 1991;1:257–65.
DeMaria EJ. Is gastric bypass superior for the surgical treatment of obesity compared with malabsorptive procedures? J Gastrointest Surg. 2004;8:401–3.
Nguyen NT, Goldman C, Rosenquist CJ, et al. Laparoscopic versus open gastric bypass: a randomized study of outcomes, quality of life, and costs. Ann Surg. 2001;234:279–89. discussion 289–91.
Schauer PR, Ikramuddin S, Gourash W, et al. Outcomes after laparoscopic Roux-en-Y gastric bypass for morbid obesity. Ann Surg. 2000;232:515–29.
Elliot K. Nutritional considerations after bariatric surgery. Crit Care Nurs Q. 2003;26:133–8.
Sechi G, Serra A. Wernicke's encephalopathy: new clinical settings and recent advances in diagnosis and management. Lancet Neurol. 2007;6:442–55.
Koffman BM, Greenfield LJ, Ali II, et al. Neurologic complications after surgery for obesity. Muscle Nerve. 2006;33:166–76.
Bloomberg RD, Fleishman A, Nalle JE, et al. Nutritional deficiencies following bariatric surgery: what have we learned? Obes Surg. 2005;15:145–54.
Buffington C, Walker B, Cowan Jr GS, et al. Vitamin D deficiency in the morbidly obese. Obes Surg. 1993;3:421–4.
Madan AK, Orth WS, Tichansky DS, et al. Vitamin and trace mineral levels after laparoscopic gastric bypass. Obes Surg. 2006;16:603–6.
Koike H, Misu K, Hattori N, et al. Postgastrectomy polyneuropathy with thiamine deficiency. J Neurol Neurosurg Psychiatry. 2001;71:357–62.
Martin PR, Singleton CK, Hiller-Sturmhofel S. The role of thiamine deficiency in alcoholic brain disease. Alcohol Res Health. 2003;27:134–42.
Chaves LC, Faintuch J, Kahwage S, et al. A cluster of polyneuropathy and Wernicke–Korsakoff syndrome in a bariatric unit. Obes Surg. 2002;12:328–34.
Mancall E. Nutritional disorders of nervous system. 3rd ed. New York: Churchill-Livingstone; 2001.
Toth C, Voll C. Wernicke's encephalopathy following gastroplasty for morbid obesity. Can J Neurol Sci. 2001;28:89–92.
Seehra H, MacDermott N, Lascelles RG, et al. Wernicke's encephalopathy after vertical banded gastroplasty for morbid obesity. BMJ. 1996;312:434.
Bozbora A, Coskun H, Ozarmagan S, et al. A rare complication of adjustable gastric banding: Wernicke's encephalopathy. Obes Surg. 2000;10:274–5.
Gorecki P, Wise L, Brolin RE, et al. Complications of combined gastric restrictive and malabsorptive procedures: part 1. Curr Surg. 2003;60:138–44.
Al-Fahad T, Ismael A, Soliman MO, et al. Very early onset of Wernicke's encephalopathy after gastric bypass. Obes Surg. 2006;16:671–2.
Escalona A, Perez G, Leon F, et al. Wernicke's encephalopathy after Roux-en-Y gastric bypass. Obes Surg. 2004;14:1135–7.
Conflict of Interest Disclosure
The authors declare that they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Iannelli, A., Addeo, P., Novellas, S. et al. Wernicke's Encephalopathy After Laparoscopic Roux-en-Y Gastric Bypass: A Misdiagnosed Complication. OBES SURG 20, 1594–1596 (2010). https://doi.org/10.1007/s11695-010-0116-0
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11695-010-0116-0