Nesidioblastosis is characterized by hyperfunction of pancreatic islets caused by hypertrophic beta cells. Postprandial symptoms of hypoglycemia are the clinical presentation of the disease. A female patient with diabetes mellitus who underwent a Roux-en-Y gastric bypass began to present postprandial symptoms of hypoglycemia. There was no radiologic (MRI) evidence of insulinoma. Selective arterial calcium-stimulation test identified hyperfunction only in the splenic artery. Laparoscopic spleen-preserving distal pancreatectomy was performed.The patient has been entirely free of any postprandial symptoms for 10 months after the partial pancreatectomy.
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Alvarez, G.C., Faria, E.N., Beck, M. et al. Laparoscopic Spleen-Preserving Distal Pancreatectomy as Treatment for Nesidioblastosis after Gastric Bypass Surgery. OBES SURG 17, 550–552 (2007). https://doi.org/10.1007/s11695-007-9096-0
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DOI: https://doi.org/10.1007/s11695-007-9096-0