Abstract
Palmatine is a valuable ingredient in Chinese medicine that is produced by Phellodendron amurense Rupr. The contents of palmatine content in root bark, trunk bark, perennial branch bark, annual branches, and leaves of the trees with different ages and geographies in Northeast China were measured by high-performance liquid chromatography. The contents of palmatine in the barks of root, trunk, and perennial branch were significantly higher than those in annual branches and leaves. The contents of palmatine in trunk bark and root bark from Lesser Khingan Mountains increased with age, which is significantly opposite to other three vegetation types. The contents of palmatine in perennial branch bark, annual bark and leaves had no significant regularity. Moreover, the contents of palmatine in samples of root bark, trunk bark, perennial branch bark and annual bark varied significantly with latitude. The nature populations of P. amurense growing at low latitude contained significantly more palmatine than those growing at high latitude. These results provide a scientific basis for the reasonable cultivation and efficient utilization of P. amurense.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Azad MAK, Yokota S, Ishiguri F, Yahara S, Yoshizawa N (2005) Histological studies of shoot regeneration system in hypocotyl-derived callus of Phellodendron amurense Rupr. J For Res 10(5):377–384
Chang Z, Zhou ZQ, Xia CM, Liu T (2012) Characteristics of paclitaxel and cephalomannine content changing in the branches of natural Japanese yew. J Beijing For Univ 34(2):71–77
Chen AH, Lee YT, Chen CY (2005) Microwave accelerated extraction and capillary electrophoresis analysis of berberine from the cortices of Phellodendron wilsonii and Phellodendron amurense. J Chem Soc-Taip 52(4):781–784
Cuellar MJ, Giner RM (2001) Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders. Fitoterapia 72:221–229
Ding L (2011) Trend reviews of Phellodendron amurense. Spec Econ Anim Plant 14:16–18
Dong J, Liang Z (2003) Analysis on the factor influencing secondary metabolite accumulation in plants. Acta Bot Boreali-Occident Sin 24(10):1979–1983
Fraser LH, Grime JP (2000) Aphid fitness on 13 grass species: a test of plant defence theory. Can J Bot 77(12):1783–1789
Fu L, Chin C (1991) China plant red data book: rare and endangered plants, 1st edn. Science Press, Beijing, pp 567–571
Garcia GE, Nicole A, Bhaskaran S, Gupta A, Kyprianou N, Kumar P (2006) Akt-and CREB-mediated prostate cancer cell proliferation inhibition by Nexrutine, a Phellodendron amurense extract. Neoplasia 8(6):523–533
Gershenzon J (1984) Changes in the levels of plant secondary metabolites under water and nutrient stress. Phytochem Adapt Stress 18:273–320
Ghosh R, Graham H, Rivas P, Tan XJ, Crosby K, Bhaskaran S, Schoolfield J, Banu J, Fernandes G, Yeh I-T, Kumar AP (2010) Phellodendron amurense bark extract prevents progression of prostate tumors in transgenic adenocarcinoma of mouse prostate: potential for prostate cancer management. Anticancer Res 30(3):857–865
Hashimoto T, Yamada Y (1994) Alkaloid biogenesis: molecular aspects. Annu Rev Plant Biol 45(1):257–285
Hiroaki S, Akira O (2012) Changes in primary and secondary metabolite levels in response to gene targeting-mediated site-directed mutagenesis of the anthranilate synthase gene in rice. Metabolites 2:1123–1138
Ikuta A, Nakamura T, Urabe H (1998) Indolopyridoquinazoline, furoquinoline and canthinone type alkaloids from Phellodendron amurense callus tissues. Phytochemistry 48(2):285–291
Institute of botany, Chinese academy of sciences (1989) endangered plant species in China. China Forestry Publishing House, Beijing, pp. 61–65
Jiang Z, Li X, Siping (2013) The effects of climate factors on the principal alkaloid content of Amur Corktree. J Northeast For Univ 40(6):14–18
Leu CH, Li CY, Yao XS, Wu TS (2006) Constituents from the leaves of Phellodendron amurense and their antioxidant activity. Chem Pharm Bull 54(9):1308–1311
Liu T, Chang Z, Wang Y, Zhou Z (2011) Differences in contents of paclitaxel and cephalomannine in Taxus cuspidate of different ages and sexes. J Northeast For Univ 39:51–53
Ma F, Zhang J (2009) Investigation of chinese key protected wild plant resources. China For Publ House, Beijing, pp 77–82
Mori H, Fuchigami M (1995) Principle of the bark Phellodendron amurense to suppress the cellular immune response: effect of Phellodendrine on cellular and humoral immune response. Planta Med 61:45–49
Mori H, Fuchigami M, Inoue N, Nagai H, Koda A, Nishioka I, Meguro K (1995) Principle of the bark Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune response. Planta Med 61:45–49
Park EK, Rhee HI, Jung HS, Ju SM, Lee YA, Lee SH, Hong SJ, Yang HI, Yoo MC, Kim KS (2007) Antiinflammatory effects of a combined herbal preparation (RAH13) of Phellodendron amurense and Coptis chinensis in animal models of inflammation. Phytother Res 21(8):746–750
Qin Y, Zhang Y, Wang Y, Yan X (2004) Determination of alkaioids content in Phellodendron amurense Rupr. by HPLC. Chem Ind For Prod 24(S1):115–118
Qin BX, Yao LP, Zhou ZQ, Zhang YH (2012) Influence of drought stress on plant physiology and berberine content of leaves in Phellodendron amurense seedlings. J Beijing For Univ 34(3):26–30
Shelton AL (2000) Variable chemical defences in plants and their effects on herbivore behaviour. Evol Ecol Res 2(2):231–249
Su WH, Zhang GF, Li XH, Qu XK (2005) Relationship between accumulation of secondary metabolism in medicinal plant and environmental condition. Chin Tradit Herb Drugs 36(9):14 Relationship between accumulation of secondary metabolism in medicinal plant and environmental condition. Chin Tradit Herb Drugs 36(9):1415
Wang W, Zu Y, Fu Y, Reichling J, Suschke U, Nokemper S, Zhang Y (2009) In vitro antioxidant, antimicrobial and anti-herpes simplex virus type 1 activity of Phellodendron amurense Rupr. from China. Am J Chin Med 37(01):195–203
Yan XF, Wang Y, Li YM (2007) Plant secondary metabolism and its response to environment. Acta Ecol Sin 27(6):2554–2562
Yang J, Zhao B, Kim YB, Zhou C, Li C, Chen Y, Li CH (2013) Agrobacterium tumefaciens-mediated transformation of Phellodendron amurense Rupr. using mature-seed explants. Mol Biol Rep 40(1):281–288
Zhou Z, Chen XJ (1997) Introduction to the main timber tree species in the world. China Forestry Publishing House, Beijing, pp 87–395
Author information
Authors and Affiliations
Corresponding authors
Additional information
Project funding: This study is supported by Special Fund for Forestry-Scientific Research in the Public Interest (Grant No. 201104066)
The online version is available at http://www.springerlink.com
Corresponding editor: Zhu Hong
Rights and permissions
About this article
Cite this article
Sun, M., Xu, L., Peng, Y. et al. Multiscale analysis of the contents of palmatine in the Nature populations of Phellodendron amurense in Northeast China. J. For. Res. 27, 265–272 (2016). https://doi.org/10.1007/s11676-015-0200-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11676-015-0200-3