Abstract
Objective: To study preliminary experience of high intensity focused ultrasound (HIFU) for unresectable malignant tumors in 75 patients. Methods: The clinical data of 75 patients with unresectable tumor was analyzed retrospectively. Results: Among 75 patients, ten out of 57 cases achieved good local control in short-term, 5 patients liver tumor, 4 patients with tumor in the chest wall and one patient with bone matestics. Seven patients had skin burn and 2 patients developed intestinal perforations. Conclusion: HIFU is a novel tool for local tumor treatment. HIFU treatment for patients with unresectable tumor in the chest wall is effective.
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Haaga J. Imaging-guided microsurgery and the future of radiology[J]. AJR 2000; 17: 303–4.
Haar T. High intensity focused ultrasound for the treatment of tumors[J]. Echocardiography 2001; 18: 317–22.
Ter-haar GR. Ultrasound focal beam surgery[J]. Ultrasound Med Biol 1995; 21: 1089–100.
Bihrle R, Foster RS, Sanghvi NT, et al. High intensity focused ultrasound for treatment of benign prostatic hyperplasia: early united states clinical experience[J]. J Urol 1994; 151: 1271–5.
Wu F, Chen WZ, Bai J, et al. Pathological changes in human malignant carcinoma treated with high-intensity focused ultrasound[J]. Ultrasound Med Biol 2001; 27: 1099–106.
Yang R, Reilly Cr, Rescorla FJ, et al. High-intensity focused ultrasound in the treatment of experimental liver cancer[J]. Arch Surg 1991; 126: 1002–9.
Goldberg SN, Gazelle GS, Mueller PR. Thermal ablation therapy for focal malignancy: a unified approach to underlying principle, and diagnostic imaging guidance[J]. Am J Roentagenol 2000; 174: 322.
Thuroff S, Chaussy C. High-intensity focused ultrasound: complications and adverse events[J]. Mol Urol 2000; 4: 183–7.
Sheen AJ, Poston GJ, Sherlock DJ. Cryotherapeutic ablation of liver tumors[J]. Br J Surg 2002; 89: 1396–401.
Goldberg SN, Gazelle GS, Halpern EF, et al. Radiofrequency tissue ablation: importance of local temperature along shape and size[J]. Acad Radiol 1996; 3: 212–8.
Miller MW, Miller DL, Brayman AA, et al. A review of in vitro bioeffect of intertial ultrasonic cavitation form a mechanic perspective[J]. Ultrasound Med Biol 1996; 22: 1131–54.
Malcolm AL, Ter Hear GR. Ablation of tissue volumes using high intensity focused ultrasound[J]. Ultrasound Med Biol 1996; 22: 659–69.
Hynynen K, Chung A, Colucci V, et al. Potential adverse effects of high-intensity focused ultrasound exposure on blood vessels in vivo[J]. Ultrasound Med Bio 1996; 22: 193–201.
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Biography: ZHENG Guo-qiang(1959–), male, doctor of medicine, Peking University School of Oncology, Beijing Cancer Hospital, majors in surgical oncology.
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Zheng, Gq. High intensity focused ultrasound for treatment unresectable malignant tumors in 75 patients. Chin. J. Cancer Res. 16, 302–304 (2004). https://doi.org/10.1007/s11670-004-0048-0
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DOI: https://doi.org/10.1007/s11670-004-0048-0