Abstract
The variation of the photoluminescence (PL) and Raman scattering spectra of CdSeTe/ZnS quantum dots (QDs) on conjugation to an antibody has been investigated. Two types of CdSeTe/ZnS QD with different emission wavelength (705 nm and 800 nm) were studied comparatively before and after conjugation to anti-pseudorabies virus antibody (AB). Nonconjugated QDs were characterized by Gaussian-type PL bands. PL shifts to higher energy and asymmetric shape of PL bands was detected in PL spectra of bioconjugated QDs. The surface-enhanced Raman scattering effect was exhibited by the bioconjugated CdSeTe/ZnS QDs, indicating that the excitation light used in the Raman study generated electric dipoles in the AB molecules. The optical bandgap of the CdSeTe core was calculated numerically as a function of its radius based on an effective mass approximation model. The energy band diagrams for non- and bioconjugated CdSeTe/ZnS QDs were obtained, revealing a type II quantum well in the CdSeTe core. The calculations show that AB dipoles, excited in the bioconjugated QDs, stimulate a change in the energy band diagram of the QDs that alters the PL spectrum. These results could be useful for improving the sensitivity of QD biosensors.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
T. Jamieson, R. Bakhshi, D. Petrova, R. Pocock, M. Imani, and A.M. Seifalian, Biomaterials 28, 4717 (2007).
D. Gerion, W.J. Parak, S.C. Williams, D. Zanchet, C.M. Micheel, and A.P. Alivisatos, J. Am. Chem. Soc. 124, 7070 (2002).
I. Brigger, C. Dubernet, and P. Couvreur, Adv. Drug Deliv. Rev. 54, 631 (2002).
J. Goicoechea, F.J. Arregui, Ig.R. Matias, in book: Sensors Based on Nanostructured Materials, Edited by F.J. Arregui (Springer Science + Business Media, LLC, New York) 2009, p. 153.
L. G. Vega Macotela, T. V. Torchynska, J. Douda, and R. Peña Sierra, Phys. Status Solidi (c) 7, 1192 (2010).
T.V. Torchynska and Yu. Vorobiev, in book: Advanced Biomedical Engineering, Edited by A. McEwan and G. D. Gargiulo (InTech, Zagreb, Croatia) 2011, pp. 143–183.
M. Dybiec, G. Chornokur, S. Ostapenko, A. Wolcott, J.Z. Zhang, A. Zajac, C. Phelan, and T. Sellers, Appl. Phys. Lett. 90, 263112 (2007).
G. Chornokur, S. Ostapenko, E. Oleynik, C. Phelan, N. Korsunska, T. Kryshtab, J. Zhang, A. Wolcott, and T. Sellers, Superlat. Microstruct. 45, 240 (2009).
F.J. Schmitt, E.G. Maksimov, P. Hätti, J. Weißenborn, V. Jeyasangar, A.P. Razjivin, V.Z. Paschenko, T. Friedrich, and G. Renger, Biochim. Biophys. Acta 1817, 1461 (2012).
L. Borkovskaa, N. Korsunska, T. Stara, O. Kolomys, V. Strelchuk, O. Rachkov, and T. Kryshtab, Appl. Surf. Sci. 281, 79 (2013).
Y.V. Vorobiev, T.V. Torchynska, V.P. Makhniy, and P. Horley, Phys. B 453, 68 (2014).
T.V. Torchynska, J. Lumin. 137, 157 (2013).
https://www.thermofisher.com/mx/es/home/brands/mole cular-probes.html.
A. Diaz Cano, S. Jiménez Sandoval, Y. Vorobiev, F. Rodriguez Melgarejo, and T. V. Torchynska, Nanotechnology 21, 134016 (2010).
T.V. Torchynska, L.I. Khomenkova, N.E. Korsunska, and B.R. Dzumaev, J. Phys. Chem. Solids 61, 937 (2000).
T.V. Torchynska, N.E. Korsunskaya, LYu Khomenkova, B.R. Dzhumaev, and S.M. Prokes, Microelectron. Eng. 51–52, 485 (2000).
T. Torchynska, Y. Vorobiev, in Advanced Biomedical Engineering, Eduted by A. McEwan and G.D. Gargiulo (InTech, Zagreb, Croatia) 2011, pp. 143–183.
Physics of II-VI compounds, Edited by A.N. Georgobiany and M.K. Sheinkman, (Nauka, Moscow, Russia) 1986, 300 p.
Physics and chemistry of II–VI compounds, Edited by M. Aven and J.S. Prener (North-Holland, Amsterdam) 1967, 625p.
G. Polupan, T.V. Torchynska, J.A. Jaramillo Gomez, and J. Douda, J. Mater. Sci.: Mater. Electron. 28, 7047 (2017).
A. Campion and P. Kambhampati, Chem. Soc. Rev. 27, 241 (1998).
F.J. García-Rodriguez, J. Gonzalez-Hernandez, F. Perez-Robles, Y.V. Vorobiev, A. Manzano-Ramirez, S. Jimenez-Sandoval, and B.S. Chao, J. Raman Spectrosc. 29, 763 (1998).
P.K. Aravind and H. Metiu, Surf. Sci. 124, 506 (1983).
T.V. Torchynska, Nanotechnology 20, 095401 (2009).
Y. Kayanuma, Phys. Rev. B. 38, 9797 (1988).
T. V. Torchynska, in: Nanocrystals and Quantum Dots of Group IV Semiconductors, Edited by T. V. Torchynska and Yu. Vorobiev (American Scientific, Stevenson Ranch, CA) pp. 1-42 (2010).
A.G. Milnes, D.L. Feucht, Heterojunctions and Metal–Semiconductor Junctions (Academic, New York and London) 427pp (1972).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Torchynska, T.V., Gomez, J.A.J., Polupan, G. et al. Impact of Antibody Bioconjugation on Emission and Energy Band Profile of CdSeTe/ZnS Quantum Dots. J. Electron. Mater. 47, 4254–4259 (2018). https://doi.org/10.1007/s11664-018-6168-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11664-018-6168-y