Skip to main content

Advertisement

SpringerLink
Log in

A review on pharmacological significance of genus Jatropha (Euphorbiaceae)

  • Review
  • Published:
Chinese Journal of Integrative Medicine Aims and scope Submit manuscript

Abstract

A number of herbs belonging to the genus Jatropha of Euphorbiaceae family are noted for their medicinal benefits. The genus Jatropha is one of the prospective biodiesel yielding crops. The plants which have been so far explored include J. curcas, J. gossypifolia, J. glandulifera, J. multifida and J. podagrica. Although, the plants of this genus are widely distributed, there is an exiguity of scientific literature proclaiming the medicinal benefits of the plants belonging to genus Jatropha. The present paper is a pragmatic approach to accrue the findings on this very significant genus.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Duke JA. Medicinal plants. Science 1985;229:1036.

    PubMed  CAS  Google Scholar 

  2. Devappa RK, Makkar HPS, Becker K. Jatropha toxicity—a review. J Toxicol Environ Health 2010;13:476–507.

    CAS  Google Scholar 

  3. Anonymous. The Wealth of India, Raw Materials, vol. 5. New Delhi: Council for Scientific and Industrial Research; 1959:293–297.

  4. Ramzi AA Mothana. Anti-inflammatory, antinociceptive and antioxidant activities of the endemic Soqotrean Boswellia elongate Balf. F. and Jatropha unicostata Balf. F. in different experimental models. Food Chem Toxicol 2011;2594–2599.

  5. Sangeetha J, Divya K, Prashanth MV, Vamsikrishna A, Rani GL. Anti-inflammatory and antibacterial activity of Jatropha curcas Linn. JPRHC 2010;2:258–262.

    Google Scholar 

  6. Dhawan BN, Patnaik GK, Rastogi RP, Singh KK, Tandon JS. Screening of Indian plants for biological activity. VI. Indian J Exp Biol 1977;43:208–219.

    Google Scholar 

  7. Uche FI, Aprioku JS. The phytochemical constituents, analgesic and anti-inflammatory effects of methanol extract of Jatropha curcas leaves in mice and Wistar albino rats. J Appl Sci Environ Manage 2008;12(4):99–102.

    Google Scholar 

  8. Eguale T, Giday M. In vitro anthelmintic activity of three medicinal plants against Haemonchus contortus. Int J Green Pharm 2009:29–34.

  9. Monteiro MVB, Bevilaqua CML, Morais SM, Machado LKA, Camurca-Vasconcelos ALF, Campello CC, et al. Anthelmintic activity of Jatropha curcas L. seeds on Haemonchus contortus. Vet Parasitol 2011;182:259–263.

    PubMed  Google Scholar 

  10. Garcia A, Delgado G. Cytotoxic cis-fused bicyclic sesquiterpenoids from Jatropha neopauciflora. J Nat Prod 2006;69:1618–1621.

    PubMed  CAS  Google Scholar 

  11. Wiedhopf RM, Trumbull ER, Cole JR. Antitumor agents from Jatropha macrorhiza (Euphorbiaceae) I: Isolation and characterization of jatropham. J Pharm Sci 1973;62:1206–1207.

    PubMed  CAS  Google Scholar 

  12. Torrance SJ, Weidhopf RM, Cole JR. Antitumour agents from Jatropha macrorhiza (Euphorbiaceae). II. Isolation and characterization of jatrophatrione. J Org Chem 1976;41:1855–1857.

    PubMed  CAS  Google Scholar 

  13. Torrance SJ, Weidhopf RM, Cole JR. Antitumour agents from Jatropha macrorhiza (Euphorbiaceae). III. Acetylaleuritolic acid. J Pharm Sci 1977;66:1348–1349.

    PubMed  CAS  Google Scholar 

  14. Oskoueian E, Abdillah N, Saad WZ, Omar AR, Ahmad S, Kuan WB, et al. Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn. J Med Plant Res 2011;5(1):49–57.

    CAS  Google Scholar 

  15. Juan L, Fang Y, Lin T, Fang C. Antitumour effects of curcin from seeds of Jatropha curcas. Acta Pharmacol Sin 2003;24:241–246.

    Google Scholar 

  16. Muanza DN, Euler KL, Wiliams L, Newman DJ. Screening of antitumour and anti-HIV activities of nine medicinal plants from Zaire. Int J Pharmacogn 1995;33:98–106.

    CAS  Google Scholar 

  17. Ankli A, Heinrich M, Bork P, Wolfram L, Bauerfeind P, Brun R, et al. Yucatec Mayan medicinal plants: evaluation based on indigenous uses. J Ethnopharmacol 2002;79:43–52.

    PubMed  Google Scholar 

  18. Taylor MD, Smith AB, Furst GT, Gunasekara SP, Bevelle CA, Cordell GA, et al. New antileukemic jatrophane derivatives from Jatropha gossypifolia: Structural and stereochemical assignment through nuclear magnetic resonance spectroscopy. J Am Chem Soc 1983;105:3177–3183.

    CAS  Google Scholar 

  19. Aiyelaagbe OO, Hamid AA, Fattorusso E, Taglialatela-Scafati O, Schroder HC, Muller WEG. Cytotoxic activity of crude extracts as well as pure components from Jatropha species, plants used extensively in African traditional medicine. Evid Based Complement Alternat Med 2011;55:1–7.

    Google Scholar 

  20. Hufford CD, Oguntimein BO. Non-polar constituents of Jatropha curcas. Lloydia 1978;41:161.

    CAS  Google Scholar 

  21. Reddy MB, Reddy KR, Reddy MN. A survey of medicinal plants of Chenchu tribes of Andhra Pradesh, India. Int J Crude Drug Res 1988;26(4):198–196.

    Google Scholar 

  22. Ferrigni NI, Putnam JE, Anderson B, Jacobsen LB, Nichols DE, Moore DS, et al. Modification and evaluation of the potato disc assay and antitumour screening of Euphorbiaceae seeds. J Nat Prod 1982;45:679–686.

    PubMed  CAS  Google Scholar 

  23. Adewunmi CO, Marquis VO. A rapid in vitro screening method for detecting schistosomicidal activity of some Nigerian medicinal plants. Int J Crude Drug Res 1983;21(4):157–159.

    Google Scholar 

  24. Macrae WD, Hudson JB, Towers GHN. Studies on the pharmacological activity of Amazonian Euphorbiaceae. J Ethnopharmacol 1988;22:143–172.

    PubMed  CAS  Google Scholar 

  25. Omoregie ES, Sisodia BS. In vitro antiplasmodial activity and cytotoxicity of leaf extracts from Jatropha tanjorensis. Pharmacologyonline 2011;2:656–673.

    Google Scholar 

  26. Balaji R, Rekha N, Deecaraman M, Manikandan L. Antimetastatic and antiproliferative activity of methanolic fraction of Jatropha curcas against B16F10 melanoma induced lung metastasis in C57BL/6 mice. Afr J Pharm Pharmacol 2009;3:547–555.

    Google Scholar 

  27. Pertino M, Schmeda-Hirschmann G, Rodriguez JA, Theoduloz C. Gastroprotective effect and cytotoxicity of terpenes from the Paraguayan crude drug “yagua rova” (Jatropha isabelli). J Ethnopharmacol 2007;111:553–559.

    PubMed  CAS  Google Scholar 

  28. Adesina SK. Studies on some plants used as anticonvulsants in Amerindian and African traditional medicine. Fitoterapia 1982;53:147–162.

    CAS  Google Scholar 

  29. Mishra SB, Vijayakumar M, Ojha SK, Verma A. Antidiabetic effect of Jatropha curcas L. leaves extract in normal and alloxan-induced diabetic rats. Int J Pharm Sci 2011;2(1):482–487.

    Google Scholar 

  30. Olayiwola G, Iwalewa EO, Omobuwajo OR, Adebajo AC, Adeniyi AA, Verspohl EJ. The antidiabetic potential of Jatropha tanjorensis leaves. Nigerian J Natur Products Med 2004;08:56–58.

    Google Scholar 

  31. Majumdar AM, Upadhye AS, Misar AV. Studies on antidiarrhoeal activity of Jatropha curcas root extract in albino mice. J Ethnopharmacol 2011;70:183–187.

    Google Scholar 

  32. Aye-than, Kulkarni HJ, Wut-hmone, Tha SJ. Anti-diarrhoeal efficacy of some Burmese indigenous drug formulations in experimental diarrhoeal test models. Int J Crude Drug Res 1989;27:195–200.

    Google Scholar 

  33. Mameesh MSL, El-Hakim LM, Hassan A. Reproductive failure in female rats fed with the fruits or seed of Jatropha curcas. Planta Med 1963;11:98.

    Google Scholar 

  34. Goonasekera MM, Gunawardana VK, Jayasena K, Mohammed SG, Balasubramaniam S. Pregnancy terminating effect of Jatropha curcas in rats. J Ethnopharmacol 1995;47:117–123.

    PubMed  CAS  Google Scholar 

  35. Abreu IC, Marinho ASS, Paes AMA, Freire SMF, Olea RSG, Borges MOR, et al. Hypotensive and vasorelaxant effects of ethanolic extract from Jatropha gossypifolia L. in rats. Fitoterapia 2003;74:650–657.

    PubMed  Google Scholar 

  36. Nayak BS, Patel KN. Anti-inflammatory screening of Jatropha curcas root, stem and leaf in albino rats. Rom J Biol · Plant Bio 2010;55(1):9–13.

    Google Scholar 

  37. Majumdar AM, Misar AV. Anti-inflammatory activity of Jatropha curcas roots in mice and rats. J Ethnopharmacol 2004;90:11–15.

    Google Scholar 

  38. Purohit MC, Reena P. Evaluation of antimicrobial and antiinflammatory activities of bark of Jatropha gossypifolia. World J Sci Technol 2011;1(10):1–5.

    CAS  Google Scholar 

  39. Bbeassor M, Kossou Y, Amegbo K, De Souza C, Koumaglo K, Denke A. Antimalarial effects of eight African medicinal plants. J Ethnopharmacol 1989;25:115–118.

    Google Scholar 

  40. Kaou AM, Mahiou-Leddet V, Hutter S, Ainouddine S, Hassani S, Yahaya I, et al. Antimalarial activity of crude extracts from nine African medicinal plants. J Ethnopharmacol 2008;116:74–83.

    PubMed  Google Scholar 

  41. Kohler I, Jennet-Siems K, Siems K, Hernandez MA, Ibarra RA, Berendsohn WG, et al. In vitro antiplasmodial investigation of medicinal plants from El Salvador. Zeitschrift fur Naturforschung 2002;57c:277–281.

    Google Scholar 

  42. Matsuse IT, Lim A, Hattori M, Correa M, Gupta MP. A search of anti-viral properties in Panamanian medicinal plants. The effects on HIV and its essential enzymes. J Ethnopharmacol 1999;64(1):15–22.

    PubMed  CAS  Google Scholar 

  43. Bhaskarwar B, Itankar P, Fuke A. Evaluation of antimicrobial activity of medicinal plant Jatropha podagrica Hook. Roum Biotechnol Lett 2008;13:3873–3877.

    Google Scholar 

  44. Akinpelu David A, Aiyegoro Olayinka A, Okoh Anthony I. The bioactive potentials of two medicinal plants commonly used as folklore remedies among some tribes in West Africa. Afr J Biotechnol 2009;8:1660–1664.

    Google Scholar 

  45. Igbinosa OO, Igbinosa EO, Aiyegoro OA. Antimicrobial activity and phytochemical screening of stem bark extracts from Jatropha curcas (Linn). Afr J Pharm Pharmacol 2009;3(2):58–62.

    Google Scholar 

  46. Kalimuthu K, Vijayakumar S, Senthilkumar R. Antimicrobial activity of the biodiesel plant, Jatropha curcas L. Int J Pharm BioSci 2010;1(3):1–5.

    Google Scholar 

  47. Sharma A, Saxena S, Rani U, Rajore S, Batra A. Broadspectrum antimicrobial properties of medicinally important plant Jatropha curcas L. Int J Pharm Sci Review Res 2010;4(3):11–14.

    Google Scholar 

  48. Aiyelaagbe OO, Adeniyi BA, Fatunsin OF, Arimah BD. In vitro antimicrobial activity and phytochemical analysis of Jatropha curcas roots. Internat J Pharmacol 2007;3(1):106–110.

    Google Scholar 

  49. Oyi AR, Onalapo JA, Haruna AK, Morah CO. Antimicrobial screening and stability studies of the crude extract of Jatropha curcas Linn latex (Euphorbiaceae). Nigerian J Pharm Sci 2007;6(2):14–20.

    Google Scholar 

  50. Elegami AA, Almagboul AZ, Omer MEA, Tohami MSE. Sudanese plants used in folkloric medicine: screening for antibacterial activity. Part X. Fitoterapia 2001;72:810–817.

    PubMed  CAS  Google Scholar 

  51. Aiyelaagbe OO, Adesogan K, Ekundayo O, Sloer JB. Antibacterial diterpenoids from Jatropha podagrica Hook. Phytochemistry 2007;68:2420–2425.

    PubMed  CAS  Google Scholar 

  52. Marquez B, Neuville L, Moreau NJ, Genet JP, Santos AF, Andrade MCC, et al. Multidrug resistance reversal agent from Jatropha elliptica. Phytochemistry 2005;66:1804–1811.

    PubMed  CAS  Google Scholar 

  53. Daniyan SY, Galadima M, Ijah UJJ, Odama LE, Yusuf AY, Abbas Y. Antibacterial activity of some Nigerian plants against methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA). Advanced Scholars 2011;1(1):8–14.

    Google Scholar 

  54. Daniyan SY, Abalaka ME, Elemba OM, d Aransiola SA. In vitro antimicrobial activity and phytochemical screening of Jatropha curcas seed extract. Int Res J Pharm 2011;2(7):60–64.

    CAS  Google Scholar 

  55. Aiyelaagbe OO. Antibacterial activity of Jatropha multifida roots. Fitoterapia 2000;72:544–546.

    Google Scholar 

  56. Hamza OJM, Beukel CJPB, Matee MIN, Moshi MJ, Mikx FHM, Selemani HO, et al. Antifungal activity of some Tanzanian plants used traditionally for the treatment of fungal infections. J Ethnopharmacol 2006;108:124–132.

    PubMed  Google Scholar 

  57. Srinivasan D, Nathan S, Suresh T, Perumalsamy PL. Antimicrobial activity of certain Indian medicinal plants used in folkloric medicine. J Ethnopharmacol 2001;74:217–220.

    PubMed  CAS  Google Scholar 

  58. Seth R, Sarin R. Analysis of the phytochemical content and anti-microbial activity of Jatropha gossypifolia L. Arch Appl Sci Res 2010;2:285–291.

    CAS  Google Scholar 

  59. Falodun A, Josephs GC, Okeri HA, Oribhabor A. Partial chromatographic characterization and antimicrobial evaluation of Jatropha gossypifolia extract and its fractions. Biosci Res Communic 2010;22(3):167–174.

    Google Scholar 

  60. Awachie PIA, Ugwu FO. Preliminary investigation of the antimicrobial and brine shrimp lethality property of some Nigerian medicinal plants. Int J Pharmacogn 1997;35:338–343.

    Google Scholar 

  61. Sriprang S, Sriprang N, Sumpradit T, Dawan S. Antibacterial activities of crude extracts from physic nut (Jatropha curcas) seed residues. Sci Asia 2010;36:346–348.

    CAS  Google Scholar 

  62. Xiao J, Zhang H, Niu L, Wang X. Efficient screening of a novel antimicrobial peptide from Jatropha curcas by cell membrane affinity chromatography. J Agr Food Chem 2011;59:1145–1151.

    CAS  Google Scholar 

  63. Hussain HSN, Deeni YY. Plants in Kano ethnomedicine; screening for antimicrobial activity and alkaloids. Int J Pharmacogn 1991;29(1):51–56.

    Google Scholar 

  64. Saetae, Donlaporn, Suntornsuk W. Antifungal activities of ethanolic extract from Jatropha curcas seed cake. J Microbiol Biotechn 2010;20:319–324.

    CAS  Google Scholar 

  65. Le Grand A, Wondergem PA, Verpoorte R, Pousset JL. Anti-infectious phytotherapies of the tree-savanah of Senegal (West Africa). II. Antimicrobial activity of 33 species. J Ethnopharmacol 1988;22(1):25–31.

    PubMed  Google Scholar 

  66. Yasuraoka KJ, Hashuguchi J, Blas BL. Laboratory assessment of the molluscicidal activity of the plant Jatropha curcas against Oncoelania snail. Proceedings of phillipine-Japan joint conference on schistosomiasis research and control, Manila, Japan International Cooperative Agency 1980:110–112.

  67. Asthana A, Mall HV, Dixit K, Gupta S. Fungitoxic properties of latex of plants with special reference to that of Croton bonplandianus Baill. Int J Crude Drug Res 1989;27(1):25–58.

    Google Scholar 

  68. Elkington BG, Southavong B, Sydara K, Souliya O, Vanthanouvong M, Nettavong K, et al. Biological evaluation of plants of Laos used in the treatment of tuberculosis in Lao traditional medicine. Pharm Bio 2009;47(1):26–33.

    Google Scholar 

  69. Maunza DNB, Kim BW, Euler KL, Williams L. Antibacterial and antifungal activities of nine medicinal plants from Zaire. Int J Pharmacogn 1994;32:337–345.

    Google Scholar 

  70. Madhumati S, Mohan MSS, Radha R. Anti-microbial properties of crude fruit extracts of Jatropha gossypifolia. J Med Aromat Plant Sci 2000;22(1B);717–720.

    Google Scholar 

  71. Suhaili Z, Yeo CC, Yasin HN, Badaludin NA, Zakaria ZA. Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria. Afr J Microbiol Res 2011;5:5147–5154.

    CAS  Google Scholar 

  72. Sundari J, Selvaraj R, Prasad NR. Antimicrobial and antioxidant potential of root bark extracts from Jatropha curcas (Linn). J Pharm Res 2011;4:3743–3746.

    Google Scholar 

  73. Namuli A, Abdullah N, Sieo CC, Zuhainis SW, Oskoueian E. Phytochemical compounds and antibacterial activity of Jatropha curcas L. extracts. J Med Plants Res 2011;5:3982–3990.

    CAS  Google Scholar 

  74. Oboh FOJ, Masodje HI. Nutritional and antimicrobial properties of Jatropha tanjorensis leaves. Am-Euras J Sci Res 2009;4(1):7–10.

    CAS  Google Scholar 

  75. James O, Unekwojo EG, Ojochenemi AA. Assessment of biological activities: A comparison of Pergularia daemia and Jatropha curcas leaf extracts. Br Biotechnol J 2011;1(3):85–100.

    Google Scholar 

  76. Gallegos-Tintore S, Torres-Fuentes C, Martinez-Ayala AL, Solorza-Feria J, Alaiz M, Giron-Calle J, et al. Antioxidant and chelating activity of Jatropha curcas L. protein hydrolysates. International conference on food innovation, food innova 2010, 25–29 Oct. Universidad Politecnica de Valencia: 1–4.

  77. Diwani GE, Rafle SE, Hawash S. Antioxidant activity of extracts obtained from residues of nodes, leaves, stem and root of Egyptian Jatropha curcas. Afr J Pharm Pharmacol 2009;3(11):521–530.

    Google Scholar 

  78. Desmarchelier C, Repetto M, Coussio, Llesuy S, Ciccia G. Total reactive antioxidant capacity (TRAP), total antioxidant reactivity (TAR) of medicinal plants used in Southwest Amazonia (Bolivia and Peru). Int J Pharmacogn 1997;35:288–296.

    Google Scholar 

  79. Igbinosa OO, Igbinosa IH, Chigor VN, Uzunuigbe OE, Oyedemi SO, Odjadjare EO, et al. Polyphenolic contents and antioxidant potential of stem bark extracts from Jatropha curcas (Linn). Int J Mol Sci 2011;12:2958–2971.

    PubMed  CAS  Google Scholar 

  80. Taylor RSL, Hudson JB, Manandhar NP, Towers GHN. Antiviral activities of medicinal plants of southern Nepal. J Ethnopharmacol 1996;53:97–104.

    PubMed  CAS  Google Scholar 

  81. Gupta A, Gupta R. A survey of plants for presence of cholinesterase activity. Phytochemistry 1997;46(5):827–831.

    CAS  Google Scholar 

  82. Oduola T, Adeosun GO, Oduola TA, Avwioro GO, Oyeniyi MA. Mechanism of action of J. gossypifolia stem latex as a haemostatic agent. Eur J Gen Med 2005;2:140–143.

    Google Scholar 

  83. Kone-Bamba D, Pelissier Y, Ozoukou ZF, Kouao D. Hemostatic activity of 216 plants used in traditional medicine in the Ivory Coast. Plant Med Phytother 1987;21:122–130.

    Google Scholar 

  84. Balaji R, Suba V, Rekha N, Deecaraman M. Hepatoprotective activity of methanolic fraction of Jatropha curcas on Aflatoxin B1 induced hepatic carcinoma. Int J Ph Sci 2009;1:287–296.

    Google Scholar 

  85. Adebowale KO, Adedire CO. Chemical composition and insecticidal properties of the underutilized Jatropha curcas seed oil. Afr J Biotechnol 2006;5:901–906.

    CAS  Google Scholar 

  86. Wink M, Koschmieder C, Sauerwein M, Sporer F. Phorbol esters of J. curcas—Biological activities and potential applications. In: Gubitz, G.M., Mittelbach, M., Trabi, M. (Eds.), Biofuels and Industrial Products from Jatropha curcas. DBV Graz 1997;160–166.

  87. Tomass Z, Hadis M, Taye A, Mekonnen Y, Petros B. Larvicidal effects of Jatropha curcas L. against Anopheles arabiensis Diptera: Culicidea. MEJS 2011;3(1):52–64.

    Google Scholar 

  88. Consoli RAGB, Mendes NM, Pereira J, Santos BDS, Lamounier MA. Larvicidal properties of plant extracts against Aedes fluviatilis (Lutz) (Diptera: Culicidae) in the laboratory. Mem Inst Oswaldo Cruz (Rio De Janiero) 1988;83(1):87–93.

    CAS  Google Scholar 

  89. Adewunmi CO, Marquis VO. Molluscicidal evaluation of some Jatropha species grown in Nigeria. Quart J Crude Drug Res 1980;18(3):141–145.

    CAS  Google Scholar 

  90. Liu SY, Sporer F, Wink M, Jourdane J, Henning R, Li YL, et al. Anthraquinones in Rheum palmatum and Rumex dentatus (Polygonaceae), and phorbol esters Jatropha curcas (Euphorbeaceae) with molluscicidal activity against the schistosome vector snails Oncomelania, Biophalaria and Bulinus. Trop Med Int Health 1997;2:179–188.

    PubMed  CAS  Google Scholar 

  91. El Kheir YM, El Tohami MS. Investigation of molluscicidal activity of certain Sudanese plants used in folk medicine. I. A preliminary biological screening for molluscicidal activity of certain Sudanese plants used in folk medicine. J Trop Med Hyg 1979;82:237–241.

    PubMed  Google Scholar 

  92. Singh A, Agarwal RA. Molluscicidal activity of Euphorbiales against the snail Indoplanorbis exustus. Acta Hydrochima et Hydrobiologica 1992;20:262–264.

    CAS  Google Scholar 

  93. Adewunmi CO, Marquis VO. Evaluation of the effects of environmental factors on molluscicidal properties of Aridan (Tetrapleura tetraptera), Lapalapa pupa (Jatropha gossypifolia), Endod (Phytolacca dodecandra) and Bayluscide. Phytother Res 1987;1(2):69–72.

    CAS  Google Scholar 

  94. Devappa RK, Makkar HPS, Becker K. Jatropha toxicity-a review. J Toxicol Environm Health (Part B) 2010;13:476–507.

    CAS  Google Scholar 

  95. Gandhi VM, Cherian KM, Mulky MJ. Toxicological studies on ratanjyot oil. Food Chem Toxicol 1995;33(1):39–42.

    PubMed  CAS  Google Scholar 

  96. Abdu-Aguye I, Sannusi RA, Alafiya-Tayo, Bhusnurmath, SR. Acute toxicity studies with Jatropha curcas L. Human Toxicol 1986;5:269–274.

    CAS  Google Scholar 

  97. Abdel Gadir WS, Onsa TO, Ali WEM, El Badwi SMA, Adam SEI. Comparative toxicity of Croton macrostachys, Jatropha curcas and Piper abyssinica seeds in Nubian goats. Small Rumin Res 2003;48:61–67.

    Google Scholar 

  98. Rakshit KD, Darukeshwara J, Rathina Raj K, Narasimhanmurthy K, Saibaba P, Bhagya S. Toxicity studies of detoxified Jatropha meal (Jatropha curcas) in rats. Food Chem Toxicol 2008;46:3621–3625.

    PubMed  CAS  Google Scholar 

  99. Omobuwajo OR, Alade GO, Akanmu MA, Obuotor EM, Osasan SA. Microscopic and toxicity studies on the leaves of Jatropha tanjorensis. Afr J Pharm Pharmacol 2011;5(1):12–17.

    Google Scholar 

  100. Katole S, Saha SK, Sastry VRB, Lade MH, Prakash B. Intake, blood metabolites and hormonal profile in sheep fed processed Jatropha (Jatropha curcas) meal. Anim Feed Sci Technol 2011;170:21–26.

    CAS  Google Scholar 

  101. Li CY, Devappa RK, Liu JX, Lv JX, Makkar HPS, Becker K. Toxicity of Jatropha curcas phorbol esters in mice. Food Chem Toxicol 2010;48:620–625.

    PubMed  CAS  Google Scholar 

  102. Makkar HPS, Kumar V, Oyeleye OO, Akinleye AO, Angulo-Escante MA, Becker K. Jatropha platyphyll, a new nontoxic Jatropha species: Physical properties and chemical constituents including toxic and antinutritional factors of seeds. Food Chem 2011;125:63–71.

    CAS  Google Scholar 

  103. Esimone CO, Nworu CS, Jackson CL. Cutaneous wound healing activity of a herbal ointment containing the leaf extract of Jatropha curcas L. (Euphorbiaceae). Int J Appl Res Nat Prod 2008;1(4):1–4.

    Google Scholar 

  104. Shetty S, Udupa SL, Udupa AL, Vollala VR. Wound healing activities of bark extract of Jatropha curcas Linn in albino rats. Saudi Med J 2006;27:1473–1476.

    PubMed  Google Scholar 

  105. Villegas LF, Fernandez ID, Maldonado H, Torres R, Zavaleta A, Vaisberg AJ, et al. Evaluation of the woundhealing activity of selected traditional medicinal plants from Peru. J Ethnopharmacol 1997;55:193–200.

    PubMed  CAS  Google Scholar 

  106. Marroquin EA, Blanco JA, Granados S, Caceres A, Morales C. Clinical trial of Jatropha curcas sap in the treatment of common warts. Fitoterapia 1997;68(2):160–162.

    Google Scholar 

  107. Osoniyi O, Onajobi F. Coagulant and anticoagulant activities in Jatropha curcas latex. J Ethnopharmacol 2003;89(1):101–105.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Guru Jambheshwar University of Science and Technology-Pharmaceutical Sciences, Hisar, 125001, India

    Surendra Kr. Sharma & Harneet Singh

Authors
  1. Surendra Kr. Sharma
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Harneet Singh
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Harneet Singh.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sharma, S.K., Singh, H. A review on pharmacological significance of genus Jatropha (Euphorbiaceae). Chin. J. Integr. Med. 18, 868–880 (2012). https://doi.org/10.1007/s11655-012-1267-8

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11655-012-1267-8

Keywords

Search

Navigation