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Magnetic resonance imaging of Alzheimer’s disease: from diagnosis to therapeutic evaluation

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Abstract

Alzheimer’s disease (AD) is a devastating late-life dementia that produces progressive loss of memory and mental faculties in elderly people. It is important to identify the earliest evidence of AD and to monitor the development of this disease for us to make positive response to its management. Magnetic resonance imaging (MRI) is powerful to image the tissue or organ without damnification. MRI can be employed to diagnose the early AD development and monitor the key biomarker development in AD. MRI may be helpful not only in diagnosing early AD, but also in evaluating its development. This article reviews the progress of MRI on the diagnosis and detection of AD, and makes comments on its therapeutic application.

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Authors and Affiliations

  1. Beijing Military General Hospital, Beijing, 100700, China

    Xue-mei Gu  (顾雪梅)

  2. Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing, 100191, China

    Zhao-feng Jiang  (姜招峰) & Han-chang Huang  (黄汉昌)

  3. College of Arts and Science, Beijing Union University, Beijing, 100191, China

    Zhao-feng Jiang  (姜招峰) & Han-chang Huang  (黄汉昌)

Authors
  1. Xue-mei Gu  (顾雪梅)
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  2. Zhao-feng Jiang  (姜招峰)
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  3. Han-chang Huang  (黄汉昌)
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Corresponding author

Correspondence to Xue-mei Gu  (顾雪梅).

Additional information

Supported by Funding Project for Academic Human Resources Development in Instituions of Higher Learning Under the Jurisdiction of Beijing Municipality (PHR No. 20090513), Scientific Research Common Program of Beijing Municipal lomission of Education (No. KM 201011417002)

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Gu, Xm., Jiang, Zf. & Huang, Hc. Magnetic resonance imaging of Alzheimer’s disease: from diagnosis to therapeutic evaluation. Chin. J. Integr. Med. 16, 276–282 (2010). https://doi.org/10.1007/s11655-010-0276-8

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  • DOI: https://doi.org/10.1007/s11655-010-0276-8

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