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Survival in Total Preoperative vs. Perioperative Chemotherapy for Patients with Metastatic High-Grade Appendiceal Adenocarcinoma Undergoing CRS/HIPEC

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Journal of Gastrointestinal Surgery

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References

  1. Benedix F, Reimer A, Gastinger I, Mroczkowski P, Lippert H, Kube R. Primary appendiceal carcinoma--epidemiology, surgery and survival: results of a German multi-center study. Eur J Surg Oncol. 2010;36(8):763-71. doi:https://doi.org/10.1016/j.ejso.2010.05.025.

    Article  CAS  PubMed  Google Scholar 

  2. The Chicago Consensus on peritoneal surface malignancies: Management of appendiceal neoplasms. Cancer. 2020;126(11):2525-33. doi:https://doi.org/10.1002/cncr.32881.

    Article  Google Scholar 

  3. Milovanov V, Sardi A, Ledakis P, Aydin N, Nieroda C, Sittig M et al. Systemic chemotherapy (SC) before cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) in patients with peritoneal mucinous carcinomatosis of appendiceal origin (PMCA). Eur J Surg Oncol. 2015;41(5):707-12. doi:https://doi.org/10.1016/j.ejso.2015.01.005.

    Article  CAS  PubMed  Google Scholar 

  4. Kolla BC, Petersen A, Chengappa M, Gummadi T, Ganesan C, Gaertner WB et al. Impact of adjuvant chemotherapy on outcomes in appendiceal cancer. Cancer Med. 2020;9(10):3400-6. doi:https://doi.org/10.1002/cam4.3009.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Blackham AU, Swett K, Eng C, Sirintrapun J, Bergman S, Geisinger KR et al. Perioperative systemic chemotherapy for appendiceal mucinous carcinoma peritonei treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. J Surg Oncol. 2014;109(7):740-5. doi:https://doi.org/10.1002/jso.23547.

    Article  PubMed  Google Scholar 

  6. Lieu CH, Lambert LA, Wolff RA, Eng C, Zhang N, Wen S et al. Systemic chemotherapy and surgical cytoreduction for poorly differentiated and signet ring cell adenocarcinomas of the appendix. Ann Oncol. 2012;23(3):652-8. doi:https://doi.org/10.1093/annonc/mdr279.

    Article  CAS  PubMed  Google Scholar 

  7. Sugarbaker PH, Bijelic L, Chang D, Yoo D. Neoadjuvant FOLFOX chemotherapy in 34 consecutive patients with mucinous peritoneal carcinomatosis of appendiceal origin. J Surg Oncol. 2010;102(6):576-81. doi:https://doi.org/10.1002/jso.21679.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

Authors

Contributions

• RB Morgan: protocol/project development, data collection or management, data analysis, manuscript writing/editing.

• A Yan: protocol/project development, data collection or management, data analysis.

• A Dhiman: protocol/project development, data analysis, manuscript editing.

• A Shergill: protocol/project development, manuscript editing.

• B Polite: protocol/project development, manuscript editing.

• KK Turaga: protocol/project development, manuscript writing/editing.

• OS Eng: protocol/project development, data analysis, manuscript writing/editing.

Corresponding author

Correspondence to Oliver S. Eng.

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Ethics Approval

Retrospective review and collection of patient data was approved by the University of Chicago institutional review board (protocol # 19–0793). No further approval was required for this retrospective study.

Conflict of Interest

The authors declare no competing interests.

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Poster Presentation: American Society of Clinical Oncology Gastrointestinal Cancers Symposium. San Francisco, CA. January 22, 2022. Poster Presentation: International Conference on Surgical Cancer Care and Advanced Cancer Therapies. Dallas, TX. March 11, 2022.

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Morgan, R.B., Yan, A., Dhiman, A. et al. Survival in Total Preoperative vs. Perioperative Chemotherapy for Patients with Metastatic High-Grade Appendiceal Adenocarcinoma Undergoing CRS/HIPEC. J Gastrointest Surg 26, 2591–2594 (2022). https://doi.org/10.1007/s11605-022-05423-9

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  • DOI: https://doi.org/10.1007/s11605-022-05423-9

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