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Current Advances in Minimally Invasive Surgical Management of Perihilar Cholangiocarcinoma

  • Review Article
  • Published:
Journal of Gastrointestinal Surgery Aims and scope

Abstract

Background

While the safety of minimally invasive surgery (MIS) has been reported for several liver malignancies, the role of MIS in the management of perihilar cholangiocarcinoma (pCCA) has been poorly defined.

Methods

A systematic review of the literature was performed utilizing MEDLINE/PubMed and Web of Science databases up to January 2020 to assess the safety and feasibility of MIS in the management of patients with pCCA.

Results

Limited data exist on the MIS approach to treat pCCA. Staging laparoscopy carries a low diagnostic yield and typically is used only in select patients with high suspicion of metastatic disease. Data on the use of MIS approach for resection of pCCA have largely been limited to case reports or small case series. A MIS approach to pCCA resection has been demonstrated to be feasible and safe, yet in most series the surgeon failed to include resection of the caudate lobe. Given that caudate lobe involvement occurs in 31–98% of patients with pCCA, incomplete resection of the caudate lobe may be associated with higher local recurrence. More recently, several surgeons have reported complete R0 surgical with removal of the caudate lobe using a MIS approach. While patients may have a shorter length-of-stay, the true benefit of the MIS approach for pCCA needs to be better defined.

Conclusions

MIS may be a safe and feasible approach at high-volume centers with robust expertise in the management of patients with pCCA. Further studies with larger number of patients are required prior to universal application of MIS for pCCA.

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Author information

Authors and Affiliations

  1. Division of Surgical Oncology, Department of Surgery, University of Wisconsin School of Medicine, Madison, WI, USA

    Amir A. Rahnemai-Azar & Sharon M. Weber

  2. Division of Surgical Oncology, Department of Surgery, University of Washington School of Medicine, Seattle, WA, USA

    Arezou Abbasi

  3. Division of Surgical Oncology, Department of Surgery, The Ohio State University College of Medicine, Columbus, OH, USA

    Diamantis I. Tsilimigras & Timothy M. Pawlik

  4. Department of Surgery, The Urban Meyer III and Shelley Meyer Chair for Cancer Research, Surgery, Oncology, Health Services Management and Policy, The Ohio State University Wexner Medical Center, Columbus, OH, USA

    Timothy M. Pawlik

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  1. Amir A. Rahnemai-Azar
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  2. Arezou Abbasi
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  3. Diamantis I. Tsilimigras
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  5. Timothy M. Pawlik
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Correspondence to Timothy M. Pawlik.

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Rahnemai-Azar, A.A., Abbasi, A., Tsilimigras, D.I. et al. Current Advances in Minimally Invasive Surgical Management of Perihilar Cholangiocarcinoma. J Gastrointest Surg 24, 2143–2149 (2020). https://doi.org/10.1007/s11605-020-04639-x

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  • DOI: https://doi.org/10.1007/s11605-020-04639-x

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