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Ten-year Outcome of Laparoscopic Antireflux Surgery

  • 2008 ssat poster presentation
  • Published:
Journal of Gastrointestinal Surgery Aims and scope

Abstract

Background

Reflux recurrence is the most common long-term complication of fundoplication. Its frequency was independent from the type of fundoplication in randomized studies. Results for different techniques of laparoscopic antireflux surgery were retrospectively evaluated after 10 years.

Methods

From 1992 to 1997, 120 patients had primary laparoscopic fundoplication with a “tailored approach” (type of wrap chosen according to esophageal peristalsis): 88 received a Nissen, 22 an anterior, and 10 a Toupet fundoplication. Follow-up of 87% of the patients included disease-related questions and the gastrointestinal quality-of-life index (GIQLI).

Results

Of the patients, 89% would select surgery again. Heartburn was reported by 30% of the patients. Regurgitations were noted from 15% of patients after a Nissen, 44% after anterior fundoplication, and 10% after a Toupet (p = 0.04). Twenty-eight percent were on acid-suppressive drugs again. Following Nissen fundoplication, proton pump inhibitors were less frequently used (p = 0.01) and on postoperative pH-metry reflux recurrence rate was lower (p = 0.04). The GIQLI was 110 ± 24 without significant differences for the type of fundoplication.

Discussion

Ten years after laparoscopic fundoplication, overall outcome is good. A quarter of the patients are on acid-suppressive drugs. Nissen fundoplication appears to control reflux better than a partial fundoplication.

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References

  1. Lundell L, Abrahamsson H, Ruth M, Rydberg L, Lönroth H, Olbe L. Long-term results of a prospective randomized comparison of total fundic wrap (Nissen-Rossetti) or semifundoplication (Toupet) for gastroesophageal reflux. Br J Surg 1996;83:830–835. doi:10.1002/bjs.1800830633.

    Article  PubMed  CAS  Google Scholar 

  2. Fibbe C, Layer P, Keller J, Strate U, Emmermann A, Zornig C. Esophageal motility in reflux disease before and after fundoplication: a prospective, randomized, clinical, and manometric study. Gastroenterology 2001;121:5–14. doi:10.1053/gast.2001.25486.

    Article  PubMed  CAS  Google Scholar 

  3. Baigrie RJ, Watson DI, Myers JC, Jamieson GG. Outcome of laparoscopic Nissen fundoplication in patients with disordered preoperative peristalsis. Gut 1997;40:381–385.

    PubMed  CAS  Google Scholar 

  4. Hagedorn C, Jonson C, Lonroth H, Ruth M, Thune A, Lundell L. Efficacy of an anterior as compared with a posterior laparoscopic partial fundoplication: results of a randomized, controlled clinical trial. Ann Surg 2003;238:189–196.

    PubMed  Google Scholar 

  5. Engstrom C, Lonroth H, Mardani J, Lundell L. An anterior or posterior approach to partial fundoplication? Long-term results of a randomized trial. World J Surg. 2007;31:1223–1227. doi:10.1007/s00268-007-9004-8.

    Article  Google Scholar 

  6. Patti MG, Robinson T, Galvani C, Gorodner MV, Fisichella PM, Way LW. Total fundoplication is superior to partial fundoplication even when esophageal peristalsis is weak. J Am Coll Surg 2004;198:863–869. doi:10.1016/j.jamcollsurg.2004.01.029.

    Article  PubMed  Google Scholar 

  7. Dallemagne B, Weerts J, Markiewicz S, Dewandre JM, Wahlen C, Monami B et al. Clinical results of laparoscopic fundoplication at ten years after surgery. Surg Endosc. 2006;20:159–165. doi:10.1007/s00464-005-0174-x.

    Article  PubMed  CAS  Google Scholar 

  8. Dallemagne B, Weerts JM, Jehaes C, Markiewicz S, Lombard R. Laparoscopic Nissen fundoplication: preliminary report. Surg Laparosc Endosc 1991;1:138–143.

    PubMed  CAS  Google Scholar 

  9. Kelly JJ, Watson DI, Chin KF, Devitt PG, Game PA, Jamieson GG. Laparoscopic Nissen fundoplication: clinical outcomes at 10 Years. J Am Coll Surg 2007;205:570–575. doi:10.1016/j.jamcollsurg.2007.05.024.

    Article  PubMed  Google Scholar 

  10. Eypasch E, Wood DS, Williams JI, Ure B, Neugebauer E, Troidl H. Der Gastrointestinale Lebensqualitätsindex (GLQI). Ein klinimetrischer index zur befindlichkeitsmessung in der gastroenterologischen Chirurgie. Chirurg. 1993;64:264–274.

    PubMed  CAS  Google Scholar 

  11. Eypasch E, Williams JI, Wood DS, Ure BM, Schmulling C, Neugebauer E et al. Gastrointestinal Quality of Life Index: development, validation and application of a new instrument. Br J Surg 1995;82:216–222. doi:10.1002/bjs.1800820229.

    Article  PubMed  CAS  Google Scholar 

  12. Fuchs KH, Freys SM, Heimbucher J, Thiede A. Erfahrungen mit der laparoskopischen technik in der antirefluxchirurgie. Chirurg 1993;64:317–323.

    PubMed  CAS  Google Scholar 

  13. Fuchs KH, Breithaupt W, Fein M, Maroske J, Hammer I. Laparoscopic Nissen repair: indications, techniques and long-term benefits. Langenbecks Arch Surg. 2005;390:197–202. doi:10.1007/s00423-004-0489-4.

    Article  PubMed  CAS  Google Scholar 

  14. Bammer T, Hinder RA, Klaus A, Klingler PJ. Five- to eight-year outcome of the first laparoscopic Nissen fundoplications. J Gastrointest Surg. 2001;5:42–48. doi:10.1016/S1091-255X(01)80012-3.

    Article  PubMed  CAS  Google Scholar 

  15. Gockel I, Heintz A, Domeyer M, Kneist W, Trinh TT, Junginger T. Nichterosive und erosive gastroösophageale refluxerkrankung. Langzeitergebnisse der laparoskopischen anterioren Semifundoplikatio. Chirurg 2007;78:35–39. doi:10.1007/s00104-006-1246-8.

    Article  PubMed  CAS  Google Scholar 

  16. Kamolz T, Granderath FA, Schweiger UM, Pointner R. Laparoscopic Nissen fundoplication in patients with nonerosive reflux disease. Long-term quality-of-life assessment and surgical outcome. Surg Endosc 2005;19:494–500. doi:10.1007/s00464-003-9267-6.

    Article  PubMed  CAS  Google Scholar 

  17. Luostarinen M, Isolauri J, Laitinen J, Koskinen M, Keyrilainen O, Markkula H et al. Fate of Nissen fundoplication after 20 years. A clinical, endoscopical, and functional analysis. Gut 1993;34:1015–1020. doi:10.1136/gut.34.8.1015.

    Article  PubMed  CAS  Google Scholar 

  18. Spechler SJ, Lee E, Ahnen D, Goyal RK, Hirano I, Ramirez F et al. Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial. JAMA 2001;285:2331–2338. doi:10.1001/jama.285.18.2331.

    Article  PubMed  CAS  Google Scholar 

  19. Lord RV, Kaminski A, Oberg S, Bowrey DJ, Hagen JA, DeMeester SR et al. Absence of gastroesophageal reflux disease in a majority of patients taking acid suppression medications after Nissen fundoplication. J Gastrointest Surg. 2002;6:3–9. doi:10.1016/S1091-255X(01)00031-2.

    Article  PubMed  Google Scholar 

  20. Thompson SK, Jamieson GG, Myers JC, Chin KF, Watson DI, Devitt PG. Recurrent heartburn after laparoscopic fundoplication is not always recurrent reflux. J Gastrointest Surg 2007;11:642–647. doi:10.1007/s11605-007-0163-6.

    Article  PubMed  Google Scholar 

  21. Galvani C, Fisichella PM, Gorodner MV, Perretta S, Patti MG. Symptoms are a poor indicator of reflux status after fundoplication for gastroesophageal reflux disease: role of esophageal functions tests. Arch Surg 2003;138:514–518. doi:10.1001/archsurg.138.5.514.

    Article  PubMed  Google Scholar 

  22. Ludemann R, Watson DI, Jamieson GG, Game PA, Devitt PG. Five-year follow-up of a randomized clinical trial of laparoscopic total versus anterior 180 degrees fundoplication. Br J Surg 2005;92:240–243. doi:10.1002/bjs.4762.

    Article  PubMed  CAS  Google Scholar 

  23. Horvath KD, Jobe BA, Herron DM, Swanstrom LL. Laparoscopic Toupet fundoplication is an inadequate procedure for patients with severe reflux disease. J Gastrointest Surg. 1999;3:583–391. doi:10.1016/S1091-255X(99)80079-1.

    Article  PubMed  CAS  Google Scholar 

  24. Fernando HC, Luketich JD, Christie NA, Ikramuddin S, Schauer PR. Outcomes of laparoscopic Toupet compared to laparoscopic Nissen fundoplication. Surg Endosc 2002;16:905–908. doi:10.1007/s004640080007.

    Article  PubMed  CAS  Google Scholar 

  25. Rydberg L, Ruth M, Abrahamsson H, Lundell L. Tailoring antireflux surgery: a randomized clinical trial. World J Surg 1999;23:612–618. doi:10.1007/PL00012356.

    Article  PubMed  CAS  Google Scholar 

  26. Kamolz T, Wykypiel HJ, Bammer T, Pointner R. Lebensqualität nach laparoskopischer Antirefluxchirurgie—Nissen fundoplicatio. Chirurg 1998;69:947–950. doi:10.1007/s001040050519.

    Article  PubMed  CAS  Google Scholar 

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Disclosure

The corresponding author declares that none of the authors has any connections whatsoever with the companies whose products are named in this paper or with any company in competition with those companies. The presentation of the topic is impartial and the contents are entirely product-neutral.

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Correspondence to M. Fein.

Additional information

The results of the questionnaire have already been published in German in the journal ‘Der Chirurg’.

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Fein, M., Bueter, M., Thalheimer, A. et al. Ten-year Outcome of Laparoscopic Antireflux Surgery. J Gastrointest Surg 12, 1893–1899 (2008). https://doi.org/10.1007/s11605-008-0659-8

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  • DOI: https://doi.org/10.1007/s11605-008-0659-8

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