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Intervention in Necrotizing Pancreatitis: An Evidence-based Review of Surgical and Percutaneous Alternatives

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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Interventional therapy in necrotizing pancreatitis is evolving. Efforts to modify or prevent pancreatic necrosis by intra-arterial infusion of antibiotics and antiproteases have been described. Moreover, traditional approaches to the surgical management of infected pancreatic necrosis are being challenged by a host of endoscopic and percutaneous techniques. While these approaches are potentially valuable additions to interventional therapy in necrotizing pancreatitis, few evidence-based studies are available to support their supplanting more traditional approaches at this time. Cooperative evidence-based multiinstitutional studies will be required to address the validity of these proposals.

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Authors and Affiliations

  1. Department of Clinical Sciences, Florida State University College of Medicine, Tallahassee, FL, USA

    Edward L. Bradley III

  2. Department of Surgery, Indiana University Medical Center, Indianapolis, IN, USA

    Thomas J. Howard

  3. Department of Radiology, St. Joseph’s Hospital, Phoenix, AZ, USA

    Eric van Sonnenberg

  4. Department of Radiology, Virginia Mason Clinic, Seattle, WA, USA

    Mehran Fotoohi

Authors
  1. Edward L. Bradley III
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  2. Thomas J. Howard
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  3. Eric van Sonnenberg
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  4. Mehran Fotoohi
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Corresponding author

Correspondence to Edward L. Bradley III.

Additional information

SSAT Postgraduate Course: Systematic Reviews of Pancreatobiliary Disease Washington, D.C. May 20, 2007.

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Bradley, E.L., Howard, T.J., van Sonnenberg, E. et al. Intervention in Necrotizing Pancreatitis: An Evidence-based Review of Surgical and Percutaneous Alternatives. J Gastrointest Surg 12, 634–639 (2008). https://doi.org/10.1007/s11605-007-0445-z

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  • DOI: https://doi.org/10.1007/s11605-007-0445-z

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