Abstract
Objectives
In this paper we describe sonoelastography findings for idiopathic granulomatous mastitis (IGM), the clinical and radiological features of which often mimic those of breast carcinoma.
Materials and methods
In this retrospective study, sonoelastography findings for patients with pathologically proved IGM were studied. Twenty-seven patients with pathologically proved IGM were enrolled in the study. All were female, and the mean age was 37.81 years (standard deviation 7.10 years; range 24 to 56 years). Elasticity scores (ES), strain ratios (SR), and elastic diameters (ED) were evaluated for the lesions.
Results
Ten lesions (37.0 %) were diffuse, six (22.2 %) were tubular, six (22.2 %) were a mass, and five (18.5 %) were cystic in appearance on ultrasonography. On sonoelastography, mean ES ± standard deviation was 1.66 ± 0.55 (between 1.00 and 3.00); mean SR ± standard deviation was 1.10 ± 0.79 (between 0.29 and 4.00). ED was no different between grey-scale and sonoelastogram images.
Conclusions
The features of idiopathic granulomatous mastitis suggest it is benign in nature.
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References
Kessler E, Wolloch Y. Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol. 1972;58:642–6.
Poniecka AW, Krasuski P, Gal E, Lubin J, Howard L, Poppiti RJ. Granulomatous inflammation of the breast in a pregnant woman: report of a case with fine needle aspiration diagnosis. Acta Cytol. 2001;45:797–801.
Rowe PH. Granulomatous mastitis associated with a pituitary prolactinoma. Br J Clin Pract. 1984;38:32–4.
Dursun M, Yilmaz S, Yahyayev A, Salmaslioglu A, Yavuz E, Igci A, et al. Multimodality imaging features of idiopathic granulomatous mastitis: outcome of 12 years of experience. Radiol Med. 2012;117:529–38.
Kocaoglu M, Somuncu I, Ors F, Bulakbasi N, Tayfun C, Ilkbahar S. Imaging findings in idiopathic granulomatous mastitis. A review with emphasis on magnetic resonance imaging. J Comput Assist Tomogr. 2004;28:635–41.
Ozturk M, Mavili E, Kahriman G, Akcan AC, Ozturk F. Granulomatous mastitis: radiological findings. Acta Radiol. 2007;48:150–5.
Al-Khawari HA, Al-Manfouhi HA, Madda JP, Kovacs A, Sheikh M, Roberts O. Radiologic features of granulomatous mastitis. Breast J. 2011;17:645–50.
Gautier N, Lalonde L, Tran-Thanh D, El Khoury M, David J, Labelle M, et al. Chronic granulomatous mastitis: imaging, pathology and management. Eur J Radiol. 2013;82:e165–75.
Cho SH, Park SH. Mimickers of breast malignancy on breast sonography. J Ultrasound Med. 2013;32:2029–36.
Baslaim MM, Khayat HA, Al-Amoudi SA. Idiopathic granulomatous mastitis: a heterogeneous disease with variable clinical presentation. World J Surg. 2007;31:1677–81.
Itoh A, Ueno E, Tohno E, Kamma H, Takahashi H, Shiina T, et al. Breast disease: clinical application of US elastography for diagnosis. Radiology. 2006;239:341–50.
Vinayagam R, Cox J, Webb L. Granulomatous mastitis: a spectrum of disease. Breast Care. (Basel). 2009;4:251–4.
Morakkabati-Spitz N, Leutner C, Schild H, Traeber F, Kuhl C. Diagnostic usefulness of segmental and linear enhancement in dynamic breast MRI. Eur Radiol. 2005;15:2010–7.
Fink M. Elastography: a new modality of ultrasound imaging. Diagn Interv Imaging. 2013;94:485.
Barr RG, Destounis S, Lackey LB 2nd, Svensson WE, Balleyguier C, et al. Evaluation of breast lesions using sonographic elasticity imaging: a multicenter trial. J Ultrasound Med. 2012;31:281–7.
Balleyguier C, Canale S, Ben Hassen W, Vielh P, Bayou EH, Mathieu MC, et al. Breast elasticity: principles, technique, results: an update and overview of commercially available software. Eur J Radiol. 2013;82:427–34.
Balleyguier C, Ciolovan L, Ammari S, Canale S, Sethom S, Al Rouhbane R, et al. Breast elastography: the technical process and its applications. Diagn Interv Imaging. 2013;94:503–13.
Franchi-Abella S, Elie C, Correas JM. Ultrasound elastography: advantages, limitations and artefacts of the different techniques from a study on a phantom. Diagn Interv Imaging. 2013;94:497–501.
Tan SM, Teh HS, Mancer JF, Poh WT. Improving B mode ultrasound evaluation of breast lesions with real-time ultrasound elastography–a clinical approach. Breast. 2008;17:252–7.
Goddi A, Bonardi M, Alessi S. Breast elastography: a literature review. J Ultrasound. 2012;15:192–8.
Thomas A, Degenhardt F, Farrokh A, Wojcinski S, Slowinski T, Fischer T. Significant differentiation of focal breast lesions: calculation of strain ratio in breast sonoelastography. Acad Radiol. 2010;17:558–63.
Cho N, Moon WK, Kim HY, Chang JM, Park SH, Lyou CY. Sonoelastographic strain index for differentiation of benign and malignant nonpalpable breast masses. J Ultrasound Med. 2010;29:1–7.
Kumm TR, Chau A, Szabunio M. Diagnostic performance of freehand elastography with strain ratio measurement in the characterization of breast lesions referred for ultrasound guided biopsy: initial clinical results at a single cancer referral center. In: Eighth international conference on the ultrasonic measurement and imaging of tissue elasticity; 2009, Vlissingen, The Netherlands.
Zhi H, Xiao XY, Yang HY, Ou B, Wen YL, Luo BM. Ultrasonic elastography in breast cancer diagnosis: strain ratio vs 5-point scale. Acad Radiol. 2010;17:1227–33.
Zhao QL, Ruan LT, Zhang H, Yin YM, Duan SX. Diagnosis of solid breast lesions by elastography 5-point score and strain ratio method. Eur J Radiol. 2012;81:3245–9.
Sohn YM, Kim MJ, Kim EK, Kwak JY, Moon HJ, Kim SJ. Sonographic elastography combined with conventional sonography: how much is it helpful for diagnostic performance? J Ultrasound Med. 2009;28:413–20.
Insana MF, Pellot-Barakat C, Sridhar M, Lindfors KK. Viscoelastic imaging of breast tumor microenvironment with ultrasound. J Mammary Gland Biol Neoplasia. 2004;9:393–404.
Berg WA, Cosgrove DO, Dore CJ, Schafer FK, Svensson WE, Hooley RJ, et al. Shear-wave elastography improves the specificity of breast US: the BE1 multinational study of 939 masses. Radiology. 2012;262:435–49.
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Durur-Karakaya, A., Durur-Subasi, I., Akcay, M.N. et al. Sonoelastography findings for idiopathic granulomatous mastitis. Jpn J Radiol 33, 33–38 (2015). https://doi.org/10.1007/s11604-014-0378-x
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DOI: https://doi.org/10.1007/s11604-014-0378-x