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Imaging of vascular tumors with an emphasis on ISSVA classification

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Abstract

The International Society for the Study of Vascular Anomalies (ISSVA) classification is becoming the international standard classification system for vascular tumors and vascular malformations. The ISSVA classification strictly distinguishes vascular tumors (neoplastic lesions) from vascular malformations (non-neoplastic lesions) based on whether there is a proliferation of vascular endothelial cells present, and it is an extremely useful classification system for determining therapeutic measures. For vascular tumors, it is clinically significant in terms of discriminating infantile hemangioma and rapidly involuting congenital hemangioma, which are expected to spontaneously regress, from other vascular tumors requiring treatment. Needless to say, clinical courses are important for diagnosis, and it is also important for radiologists to understand imaging findings on vascular tumors because such tumors have unique findings on diagnostic images. In this paper, vascular tumors are classified based on the ISSVA classification, and clinical and imaging findings are reviewed.

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References

  1. Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F. Vascular tumors, WHO classification of tumors of soft tissue and bone. 4th ed. Lyon: IARC Press; 2013. p. 137–58.

    Google Scholar 

  2. Enjolras O. Classification and management of the various superficial vascular anomalies: hemangiomas and vascular malformations. J Dermatol. 1997;24(11):701–10.

    CAS  PubMed  Google Scholar 

  3. Léauté-Labrèze C, Dumas de la Roque E, Hubiche T, Boralevi F, Thambo JB, Taïeb A. Propranolol for severe hemangiomas of infancy. N Engl J Med. 2008;358(24):2649–51.

    Article  PubMed  Google Scholar 

  4. Restrepo R, Palani R, Cervantes LF, Duarte AM, Amjad I, Altman NR. Hemangiomas revisited: the useful, the unusual and the new. Part 1: overview and clinical and imaging characteristics. Pediatr Radiol. 2011;41(7):895–904.

    Article  PubMed  Google Scholar 

  5. Boon LM, Enjolras O, Mulliken JB. Congential hemangioma: evidence of accelerated involution. J Pediatr. 1996;128(3):329–35.

    Google Scholar 

  6. Gorincour G, Kokta V, Rypens F, Garel L, Powell J, Dubois J. Imaging characteristics of two subtypes of congenital hemangiomas: rapidly involuting congenital hemangiomas and non-involuting congenital hemangiomas. Pediatr Radiol. 2005;35(12):1178–85.

    Article  PubMed  Google Scholar 

  7. Fadell MF 2nd, Jones BV, Adams DM. Prenatal diagnosis and postnatal follow-up of rapidly involuting congenital hemangioma (RICH). Pediatr Radiol. 2011;41(8):1057–60.

    Article  PubMed  Google Scholar 

  8. Zukerberg LR, Nickoloff BJ, Weiss SW. Kaposiform hemangioendothelioma of infancy and childhood. An aggressive neoplasm associated with Kasabach-Merritt syndrome and lymphangiomatosis Am J Surg Pathol. 1993;17(4):321–8.

    Google Scholar 

  9. Gruman A, Liang MG, Mulliken JB, Fishman SJ, Burrows PE, Kozakewich HP, et al. Kaposiform hemangioendothelioma without Kasabach-Merritt phenomenon. J Am Acad Dermatol. 2005;52(4):616–22.

    Article  PubMed  Google Scholar 

  10. Cho KH, Kim SH, Park KC, Lee AY, Song KY, Chi JG, et al. Angioblastoma (Nakagawa)—is it the same as tufted angioma? Clin Exp Dermatol. 1991;16(2):110–3.

    Google Scholar 

  11. Nozaki T, Nosaka S, Miyazaki O, Makidono A, Yamamoto A, Niwa T, et al. Syndromes associated with vascular tumors and malformations: a pictorial review. Radiographics. 2013;33(1):175–95.

    Article  PubMed  Google Scholar 

  12. Tamai N, Hashii Y, Osuga K, Chihara T, Morii E, Aozasa K, et al. Kaposiform hemangioendothelioma arising in the deltoid muscle without the Kasabach-Merritt phenomenon. Skeletal Radiol. 2010;39(10):1043–6.

    Article  PubMed  Google Scholar 

  13. Kransdorf MJ, Murphey MD. Imaging of soft tissue tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2006. p. 177–85.

    Google Scholar 

  14. Poncet A, Dor L. Botryomycose humaine. Rev Chir Orthop. 1897;18:996–7.

  15. Weiss SW, Goldblum JR. Benign tumors and tumor-like lesions of blood vessels. In: Weiss SW, Goldblum JR, editors. Enzinger and Weiss’s soft tissue tumors. St. Louis: Mosby; 2001. p. 837–915.

    Google Scholar 

  16. Kamishima T, Hasegawa A, Kubota KC, Oizumi N, Iwasaki N, Minami A, et al. Intravenous pyogenic granuloma of the finger. Jpn J Radiol. 2009;27(8):328–32.

    Article  PubMed  Google Scholar 

  17. Lee G, Suh K, Lee Y, Kang I. CT findings in two cases of lobular capillary haemangioma of the nasal cavity: focusing on the enhancement pattern. Dentomaxillofac Radiol. 2012;41(2):165–8.

    Article  PubMed Central  PubMed  Google Scholar 

  18. Walker EA, Salesky JS, Fenton ME, Murphey MD. Magnetic resonance imaging of malignant soft tissue neoplasms in the adult. Radiol Clin N Am. 2011;49(6):1219–34.

    Article  PubMed  Google Scholar 

  19. Murphey MD, Fairbairn KJ, Parman LM, Baxter KG, Parsa MB, Smith WS. From the archives of the AFIP. Musculoskeletal angiomatous lesions: radiologic-pathologic correlation. Radiographics. 1995;15(4):893–917.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

The authors thank Jay Starkey, MD for valuable assistance in manuscript preparation.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, St. Luke’s International Hospital, 9-1 Akashi-Cho, Chuo-Ku, Tokyo, 104-8560, Japan

    Taiki Nozaki, Masaki Matsusako, Minobu Kamo & Yukihisa Saida

  2. Department of Diagnostic Radiology 2, Kawasaki Hospital, Kawasaki Medical School, 2-1-80, Nakasange Kita-ku, Okayama, 700-8505, Japan

    Hidefumi Mimura

  3. Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Keigo Osuga

  4. Department of Plastic Surgery and Reconstructive Surgery, St. Luke’s International Hospital, 9-1 Akashi-Cho, Chuo-Ku, Tokyo, 104-8560, Japan

    Mizuko Matsui & Naoyuki Ohtake

  5. Department of Dermatology, St. Luke’s International Hospital, 9-1 Akashi-Cho, Chuo-Ku, Tokyo, 104-8560, Japan

    Hikaru Eto

  6. Department of Pediatrics, St. Luke’s International Hospital, St. Luke’s International Hospital, 9-1 Akashi-Cho, Chuo-Ku, Tokyo, 104-8560, Japan

    Atsushi Manabe & Isao Kusakawa

  7. Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-Ku, Tokyo, 157-8535, Japan

    Yoshiyuki Tsutsumi & Shunsuke Nosaka

Authors
  1. Taiki Nozaki
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  2. Masaki Matsusako
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  3. Hidefumi Mimura
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  4. Keigo Osuga
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  5. Mizuko Matsui
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  6. Hikaru Eto
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  7. Naoyuki Ohtake
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  8. Atsushi Manabe
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  9. Isao Kusakawa
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  10. Yoshiyuki Tsutsumi
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  11. Shunsuke Nosaka
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  12. Minobu Kamo
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  13. Yukihisa Saida
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Corresponding author

Correspondence to Taiki Nozaki.

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Nozaki, T., Matsusako, M., Mimura, H. et al. Imaging of vascular tumors with an emphasis on ISSVA classification. Jpn J Radiol 31, 775–785 (2013). https://doi.org/10.1007/s11604-013-0249-x

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  • DOI: https://doi.org/10.1007/s11604-013-0249-x

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