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Diffusion-weighted MRI of renal cell carcinoma, upper tract urothelial carcinoma, and renal infection: a pictorial review

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Abstract

Diffusion-weighted (DW) magnetic resonance imaging (MRI) is a functional imaging technique that derives image contrast from differences in water molecule diffusion within tissues. DW MRI helps detect and characterize renal and urothelial malignancies, may help in differentiating some benign from malignant renal masses, and can also recognize renal and upper urinary tract infections. Patients precluded from receiving intravenous contrast agents may particularly benefit from this technique.

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References

  1. Koh D, Collins DJ. Diffusion-weighted MRI in the body: applications and challenges in oncology. AJR Am J Roentgenol. 2007;188:1622–35.

    Article  PubMed  Google Scholar 

  2. Müller MF, Prasad PV, Bimmler D, Kaiser A, Edelman RR. Functional imaging of the kidney by means of measurement of the apparent diffusion coefficient. Radiology. 1994;193:711–5.

    PubMed  Google Scholar 

  3. Bittencourt LK, Matos C, Coutinho AC. Diffusion-weighted magnetic resonance imaging in the upper abdomen: technical issues and clinical applications. Magn Reson Imaging Clin N Am. 2011;19:111–31.

    Article  PubMed  Google Scholar 

  4. Zhang J, Tehrani YM, Wang L, Ishill NM, Schwartz LH, Hricak H. Renal masses: characterization with diffusion-weighted MR imaging—a preliminary experience. Radiology. 2008;247:458–64.

    Article  PubMed  Google Scholar 

  5. Sandrasegaran K, Sundaram CP, Ramaswamy R, Akisik FM, Rydberg MP, Lin C, et al. Usefulness of diffusion-weighted imaging in the evaluation of renal masses. AJR Am J Roentgenol. 2010;194:438–45.

    Article  PubMed  Google Scholar 

  6. Wang H, Cheng L, Zhang X, Wang D, Guo A, Gao Y, et al. Renal cell carcinoma: diffusion-weighted MR imaging for subtype differentiation at 3.0 T. Radiology. 2010;257:135–43.

    Article  PubMed  Google Scholar 

  7. Taouli B, Thakur RK, Mannelli L, Babb JS, Kim S, Hecht EM, et al. Renal lesions: characterization with diffusion-weighted imaging versus contrast-enhanced MR imaging. Radiology. 2009;251:398–407.

    Article  PubMed  Google Scholar 

  8. Rosenkrantz AB, Niver BE, Fitzgerald EF, Babb JS, Chandarana H, Melamed J. Utility of the apparent diffusion coefficient for distinguishing clear cell renal cell carcinoma of low and high nuclear grade. AJR Am J Roentgenol. 2010;195:W344–51.

    Article  PubMed  Google Scholar 

  9. Yu X, Lin M, Ouyang H, Zhou C, Zhang H. Application of ADC measurement in characterization of renal cell carcinomas with different pathological types and grades by 3.0 T diffusion-weighted MRI. Eur J Radiol. 2012;81:3061–6.

    Article  PubMed  Google Scholar 

  10. Yoshida S, Masuda H, Ishii C, Tanaka H, Fujii Y, Kawakami S, et al. Usefulness of diffusion-weighted MRI in diagnosis of upper urinary tract cancer. AJR Am J Roentgenol. 2011;196:110–6.

    Article  PubMed  Google Scholar 

  11. Akita H, Jinzaki M, Kikuchi E, Sugiura H, Akita A, Mikami S, et al. Preoperative T categorization and prediction of urothelial carcinoma in renal pelvis using diffusion-weighted MRI. AJR Am J Roentgenol. 2011;197:1130–6.

    Article  PubMed  Google Scholar 

  12. Iancu AS, Colin P, Puech P, Villers A, Ouzzane A, Fantoni JC, et al. Significance of ADC value for detection and characterization of urothelial carcinoma of the upper urinary tract using diffusion-weighted MRI. World J Urol. 2013;31:13–9.

    Article  Google Scholar 

  13. Cova M, Squillaci E, Stacul F, Manenti G, Gava S, Simonetti G, et al. Diffusion-weighted MRI in the evaluation of renal lesions: preliminary results. Br J Radiol. 2004;77:851–7.

    Article  PubMed  CAS  Google Scholar 

  14. Kim S, Jain M, Harris AB, Lee VS, Babb JS, Sigmund EE, et al. T1 hyperintense renal lesions: characterization with diffusion-weighted MR imaging versus contrast-enhanced MR imaging. Radiology. 2009;251:796–807.

    Article  PubMed  Google Scholar 

  15. Verswijvel G, Vandecaveye V, Gelin G, Vandevenne J, Grieten M, Horvath M, et al. Diffusion-weighted MR imaging in the evaluation of renal infection: preliminary results. JBR-BTR. 2002;85:100–3.

    PubMed  CAS  Google Scholar 

  16. Chan JHM, Tsui EYK, Luk SH, Fung SL, Cheung YK, Chan MSM, et al. MR diffusion-weighted imaging of kidney: differentiation between hydronephrosis and pyonephrosis. Clin Imaging. 2001;25:110–3.

    Article  PubMed  CAS  Google Scholar 

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, Northwestern Memorial Hospital, 676 North St. Clair Suite 800, Chicago, IL, 60611, USA

    Jonathan R. Cogley

  2. Department of Radiology, Baystate Medical Center, 759 Chestnut Street, Springfield, MA, 01199, USA

    Dustin D. Nguyen & Dmitry Rakita

  3. Department of Radiology, Jefferson Medical College, 132 S. 10th Street, Suite 1087, Main Building, Philadelphia, PA, 19107, USA

    Peter M. Ghobrial

Authors
  1. Jonathan R. Cogley
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  2. Dustin D. Nguyen
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  3. Peter M. Ghobrial
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  4. Dmitry Rakita
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Corresponding author

Correspondence to Dustin D. Nguyen.

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Cogley, J.R., Nguyen, D.D., Ghobrial, P.M. et al. Diffusion-weighted MRI of renal cell carcinoma, upper tract urothelial carcinoma, and renal infection: a pictorial review. Jpn J Radiol 31, 643–652 (2013). https://doi.org/10.1007/s11604-013-0237-1

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  • DOI: https://doi.org/10.1007/s11604-013-0237-1

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