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Ultrasonographic elastography of the breast using acoustic radiation force impulse technology: preliminary study

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Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Purpose

The aim of this study was to investigate the clinical usefulness of acoustic radiation force impulse (ARFI) imaging for the differential diagnosis of breast lesions.

Materials and methods

We studied 40 solid mass lesions from a total of 40 patients (age range 29–67 years, mean 50 years). There were 18 benign lesions and 22 malignant tumors. ARFI imaging was performed using Virtual Touch tissue imaging. We examined the possibility of lesions seen on B-mode images being visually confirmed on ARFI images. When the lesion was visually confirmed, the lesions that were bright or dark inside were classified into patterns 1 and patterns 3, respectively. The lesions that failed to be visually confirmed were classified as pattern 2.

Results

There were 3 pattern 1 lesions and 7 pattern 2 lesions; all of these lesions were benign. The remaining 8 benign lesions and 22 malignant lesions were determined to be pattern 3. The negative predictive value was 100%.

Conclusion

ARFI imaging is a potentially promising ultrasonographic technique for the differential diagnosis of breast lesions, particularly complicated cysts without a cystic component on B-mode images.

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References

  1. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology 1995;196:123–134.

    PubMed  CAS  Google Scholar 

  2. Zonderland HM, Coerkamp EG, Hermans J, van de Vijver MJ, van Voorthuisen AE. Diagnosis of breast cancer: contribution of US as an adjunct to mammography. Radiology 1999;213:413–422.

    PubMed  CAS  Google Scholar 

  3. Flobbe K, Nelemans PJ, Kessels AG, Beets GL, von Meyenfeldt MF, van Engelshoven JM. The role of ultrasonography as an adjunct to mammography in the detection of breast cancer—a systematic review. Eur J Cancer 2002;38:1044–1050.

    Article  PubMed  CAS  Google Scholar 

  4. Cosgrove DO, Kedar RP, Bamber JC, al-Murrani B, Davey JB, Fisher C, et al. Breast diseases: color Doppler US in differential diagnosis. Radiology 1993;189:99–104.

    PubMed  CAS  Google Scholar 

  5. Raza S, Baum JK. Solid breast lesions: evaluation with power Doppler US. Radiology 1997;203:164–168.

    PubMed  CAS  Google Scholar 

  6. Itoh A, Ueno E, Tohno E, Kamma H, Takahashi H, Shiina T, et al. Breast disease: clinical application of US elastography for diagnosis. Radiology 2006;239:341–350.

    Article  PubMed  Google Scholar 

  7. Athanasiou A, Tardivon A, Tanter M, Sigal-Zafrani B, Bercoff J, Deffieux T, et al. Breast lesions: quantitative elastography with supersonic shear imaging-preliminary results. Radiology 2010;256:297–303.

    Article  PubMed  Google Scholar 

  8. Berg WA, Sechtin AG, Marques H, Zhang Z. Cystic breast masses and the ACRIN 6666 experience. Radiol Clin North Am 2010;48:931–987.

    Article  PubMed  Google Scholar 

  9. Tardivon A, El Khoury C, Thibault F, Wyler A, Barreau B, Neuenschwander S. Elastography of the breast: a prospective study of 122 lesions. J Radiol 2007;88:657–662.

    Article  PubMed  CAS  Google Scholar 

  10. Schaefer FK, Heer I, Schaefer PJ, Mundhenke C, Osterholz S, Order BM, et al. Breast ultrasound elastography: results of 193 breast lesions in a prospective study with histopathologic correlation. Eur J Radiol 2011;77:450–456.

    Article  PubMed  CAS  Google Scholar 

  11. Wojcinski S, Farrokh A, Weber S, Thomas A, Fischer T, Slowinski T, et al. Multicenter study of ultrasound real-time tissue elastography in 779 cases for the assessment of breast lesions: improved diagnostic performance by combining the BI-RADS(R)-US classification system with sonoelastography. Ultraschall Med 2010;31:484–491.

    Article  PubMed  CAS  Google Scholar 

  12. Regini E, Bagnera S, Tota D, Campanino P, Luparia A, Barisone F, et al. Role of sonoelastography in characterising breast nodules: preliminary experience with 120 lesions. Radiol Med 2010;115:551–562.

    Article  PubMed  CAS  Google Scholar 

  13. Raza S, Odulate A, Ong EM, Chikarmane S, Harston CW. Using real-time tissue elastography for breast lesion evaluation: our initial experience. J Ultrasound Med 2010;29:551–563.

    PubMed  Google Scholar 

  14. Zhi H, Xiao XY, Yang HY, Wen YL, Ou B, Luo BM, et al. Semi-quantitating stiffness of breast solid lesions in ultrasonic elastography. Acad Radiol 2008;15:1347–1353.

    Article  PubMed  Google Scholar 

  15. Cho N, Moon WK, Kim HY, Chang JM, Park SH, Lyou CY. Sonoelastographic strain index for differentiation of benign and malignant nonpalpable breast masses. J Ultrasound Med 2010;29:1–7.

    PubMed  Google Scholar 

  16. Sohn YM, Kim MJ, Kim EK, Kwak JY, Moon HJ, Kim SJ. Sonographic elastography combined with conventional sonography: how much is it helpful for diagnostic performance? J Ultrasound Med 2009;28:413–420.

    PubMed  Google Scholar 

  17. Berg WA, Campassi CI, Ioffe OB. Cystic lesions of the breast: sonographic-pathologic correlation. Radiology 2003;227:183–191.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Breast Center, Kameda Medical Center, 929 Higashi-cho, Kamogawa, 296-8602, Japan

    Mitsuhiro Tozaki & Eisuke Fukuma

  2. Division of Ultrasonographic Examination, Kameda Medical Center, Kamogawa, Japan

    Sachiko Isobe, Miki Yamaguchi, Yukari Ogawa & Kanako Homma

  3. Marketing Division, Mochida Siemens Medical Systems, Tokyo, Japan

    Masahiro Saito & Chanwoong Joo

Authors
  1. Mitsuhiro Tozaki
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  2. Sachiko Isobe
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  3. Miki Yamaguchi
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  4. Yukari Ogawa
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  5. Kanako Homma
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  6. Masahiro Saito
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  7. Chanwoong Joo
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  8. Eisuke Fukuma
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Corresponding author

Correspondence to Mitsuhiro Tozaki.

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Tozaki, M., Isobe, S., Yamaguchi, M. et al. Ultrasonographic elastography of the breast using acoustic radiation force impulse technology: preliminary study. Jpn J Radiol 29, 452–456 (2011). https://doi.org/10.1007/s11604-011-0561-2

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  • DOI: https://doi.org/10.1007/s11604-011-0561-2

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