Abstract
Soft tissue perineurioma is an uncommon benign peripheral nerve sheath tumor, although it is the most common subtype of perineuriomas. We present a case of soft tissue perineurioma in the left groin of a 48-year-old man. Precontrast computed tomography showed a homogeneous hypodense mass that showed faint enhancement. The mass appeared with hypointensity on T1-weighted magnetic resonance (MR) images and heterogeneous hyperintensity on T2-weighted MR images. Slight contrast uptake was noted on enhanced T1-weighted MR images with fat suppression. Although these CT and MR imaging findings were nonspecific, the overall imaging features are similar to those of schwannomas.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Lazarus SS, Trombetta LD. Ultrastructural identification of a benign perineurial cell tumor. Cancer 1978;41:1823–1829.
Hornick JL, Fletcher CD. Soft tissue perineurioma: clinicopathologic analysis of 81 cases including those with atypical histologic features. Am J Surg Pathol 2005;29:845–858.
Fetsch JF, Miettinen M. Sclerosing perineurioma: a clinicopathologic study of 19 cases of a distinctive soft tissue lesion with a predilection for the fingers and palms of young adults. Am J Surg Pathol 1997;21:1433–1442.
Brock JE, Perez-Atayde AR, Kozakewich HP, Richkind KE, Fletcher JA, Vargas SO. Cytogenetic aberrations in perineurioma: variation with subtype. Am J Surg Pathol 2005;29:1164–1169.
Yamaguchi U, Hasegawa T, Hirose T, Fugo K, Mitsuhashi T, Shimizu M, et al. Sclerosing perineurioma: a clinicopathological study of five cases and diagnostic utility of immunohistochemical staining for GLUT1. Virchows Arch 2003;443: 159–163.
Hirose T, Tani T, Shimada T, Ishizawa K, Shimada S, Sano T. Immunohistochemical demonstration of EMA/GLUT1-positive perineurial cells and CD34 positive fibroblastic cells in peripheral nerve sheath tumors. Mod Pathol 2003;16:293–298.
Simmons Z, Mahadeen ZI, Kothari MJ, Powers S, Wise S, Towfighi J. Localized hypertrophic neuropathy: magnetic resonance imaging findings and long-term follow-up. Muscle Nerve 1999;22:28–36.
Miyake M, Tateishi U, Maeda T, Arai Y, Seki K, Hasegawa T, et al. Sclerosing perineurioma: tumor of the hand with a short T2. Skeletal Radiol 2006;35:543–546.
Pilavaki M, Chourmouzi D, Kiziridou A, Skordalaki A, Zarampoukas T, Drevelengas A. Imaging of peripheral nerve sheath tumors with pathologic correlation: pictorial review. Eur J Radiol 2004;52:229–239.
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
Miyake, M., Tateishi, U., Maeda, T. et al. Computed tomography and magnetic resonance imaging findings of soft tissue perineurioma. Radiat Med 26, 368–371 (2008). https://doi.org/10.1007/s11604-008-0233-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11604-008-0233-z