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Fabrication of amperometric sensor for glucose detection based on phosphotungstic acid–assisted PDPA/ZnO nanohybrid composite

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Abstract

Amperometric sensor of polydiphenylamine (PDPA)/phosphotungstic acid (PTA)/zinc oxide (ZnO) on glassy carbon (GC) nanohybrid composite electrode (GC/PDPA/PTA/ZnO) fabricated via facile electrochemical deposition method. The structural geometry and surface morphology were recorded by X-ray diffraction spectrometer (XRD) and scanning electron microscopy (SEM). Electro-catalytic properties and performances of nanohybrid composite were recorded by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and chronoamperometry (CA) methods. PTA-assisted PDPA/ZnO-ME shows linear steady-state response towards glucose with superior sensitivity of 20.30 μA μM−1 cm−2, lowest detection limit 0.1 μM, and rapid response less than 2 s. The improved electro-catalytic performance towards glucose by GC/PDPA/PTA/ZnO is due to the combined existence of diphenoquinone diamine (DPDI2+) and phosphotungstic acid anion which provides a higher electro-catalytic active spots leads to more electron transport pathway for the oxidation of glucose. Interference analyses confirm the prepared nanohybrid sensor is best apt for glucose detection claims its practical biomedical application.

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Acknowledgments

The authors are grateful to the Researchers Supporting Project No.(RSP-2020/1), King Saud University, Riyadh, Saudi Arabia. Also, authors acknowledge the support from Science and Engineering Research Board (EEQ/2018/000574), New Delhi, India, and basic research support from National Institute of Technology Puducherry, Karaikal, India.

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Authors and Affiliations

  1. Nano Electrochemistry Lab (NEL), Department of Chemistry, National Institute of Technology Puducherry, Karaikal, 609-609, India

    E. Muthusankar & D. Ragupathy

  2. Department of Electronics and Communication Engineering, National Institute of Technology Puducherry, Karaikal, 609-609, India

    E. Muthusankar

  3. Department of Chemistry, College of Science, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia

    Saikh Mohammad Wabaidur & Zeid Abdullah Alothman

  4. Nanotechnology and Catalysis Research Center (NANOCAT), University of Malaya, 50603, Kuala Lumpur, Malaysia

    Mohd Rafie Johan

  5. Nano and Green Analytical Lab, Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung City, 807, Taiwan

    Vinoth Kumar Ponnusamy

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  1. E. Muthusankar
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  2. Saikh Mohammad Wabaidur
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  3. Zeid Abdullah Alothman
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  4. Mohd Rafie Johan
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  5. Vinoth Kumar Ponnusamy
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  6. D. Ragupathy
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Correspondence to D. Ragupathy.

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Muthusankar, E., Wabaidur, S.M., Alothman, Z.A. et al. Fabrication of amperometric sensor for glucose detection based on phosphotungstic acid–assisted PDPA/ZnO nanohybrid composite. Ionics 26, 6341–6349 (2020). https://doi.org/10.1007/s11581-020-03740-0

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  • DOI: https://doi.org/10.1007/s11581-020-03740-0

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