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Selective and sensitive voltammetric sensor based on modified multiwall carbon nanotubes paste electrode for simultaneous determination of l-cysteine and folic acid

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Abstract

This paper reports the selective and sensitive voltammetric determination of l-cysteine in the presence of folic acid using ethynylferrocene modified carbon nanotubes paste electrode in 0.1 M phosphate buffer solution (pH 7.0). Using square wave voltammetry, we could measure l-cysteine and folic acid in one mixture independently from each other by a potential difference of about 410 mV for the first time. Square wave voltammetric peak current of l-cysteine and folic acid increased linearly with their concentrations in the ranges of 0.2–250.0 and 1.0–500.0 μmol L−1, respectively. The detection limits of 0.07 and 0.6 μmol L−1 were achieved for l-cysteine and folic acid, respectively. The proposed voltammetric sensor was successfully applied to the determination of l-cysteine and folic acid in real samples.

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Acknowledgments

The authors wish to thank the Science and Research Branch, Islamic Azad University, Mazandaran for the support.

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Authors and Affiliations

  1. Department of Chemistry, Science and Research Branch, Islamic Azad University, Mazandaran, Iran

    Sohrab Kazemi & Hassan Karimi-Maleh

  2. Department of Organic Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran

    Rahman Hosseinzadeh

  3. Department of Mechanical Engineering, University of Tehran, Tehran, 14395-515, Iran

    Fahim Faraji

Authors
  1. Sohrab Kazemi
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  2. Hassan Karimi-Maleh
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  3. Rahman Hosseinzadeh
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  4. Fahim Faraji
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Corresponding author

Correspondence to Hassan Karimi-Maleh.

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Kazemi, S., Karimi-Maleh, H., Hosseinzadeh, R. et al. Selective and sensitive voltammetric sensor based on modified multiwall carbon nanotubes paste electrode for simultaneous determination of l-cysteine and folic acid. Ionics 19, 933–940 (2013). https://doi.org/10.1007/s11581-012-0816-7

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  • DOI: https://doi.org/10.1007/s11581-012-0816-7

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